Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue GR8 A 201 |
| Chain | Residue |
| A | ARG8 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | GOL204 |
| A | HOH302 |
| A | HOH320 |
| A | HOH350 |
| A | HOH388 |
| A | HOH392 |
| B | ARG8 |
| A | ASP25 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | PRO81 |
| A | GLY27 |
| B | VAL82 |
| B | ILE84 |
| B | HOH231 |
| B | HOH245 |
| B | HOH285 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 202 |
| Chain | Residue |
| A | ASP60 |
| A | HOH319 |
| A | HOH327 |
| A | HOH338 |
| A | HOH358 |
| A | HOH376 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH391 |
| B | ARG41 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | GLY48 |
| A | PHE53 |
| A | GR8201 |
| A | HOH309 |
| A | HOH364 |
| B | ARG8 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 101 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 102 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH233 |
| B | HOH296 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue ACT B 103 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| B | THR12 |
| B | THR12 |
| B | ILE13 |
| B | LYS14 |
| B | GLU65 |
| B | GLU65 |
| B | ILE66 |
| B | ALA67 |
| B | GLY68 |
| B | GLY68 |
| B | HOH210 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 104 |
| Chain | Residue |
| B | PRO39 |
| B | ARG41 |
| B | TYR59 |
| B | ASP60 |
| B | HOH213 |
| B | HOH230 |
| B | HOH257 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
