Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| A | 0019264 | biological_process | glycine biosynthetic process from serine |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| B | 0019264 | biological_process | glycine biosynthetic process from serine |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue SEY A 601 |
| Chain | Residue |
| A | PRO183 |
| A | LEU352 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SEY A 602 |
| Chain | Residue |
| A | ASP375 |
| A | ASN378 |
| A | TYR379 |
| A | HOH738 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SEY A 603 |
| Chain | Residue |
| A | HOH711 |
| A | VAL174 |
| A | GLU341 |
| A | SEY606 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SEY A 604 |
| Chain | Residue |
| A | TYR370 |
| A | SER373 |
| A | PRO374 |
| A | ASP375 |
| B | SER88 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SEY A 605 |
| Chain | Residue |
| A | ALA263 |
| A | TYR266 |
| A | ARG268 |
| A | ASN408 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SEY A 606 |
| Chain | Residue |
| A | ILE155 |
| A | GLN158 |
| A | SEY603 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SEY A 607 |
| Chain | Residue |
| A | GLY137 |
| A | ASN345 |
| A | ASN346 |
| A | PHE349 |
| A | PRO350 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SEY A 608 |
| Chain | Residue |
| A | HIS196 |
| A | HOH816 |
| B | PRO195 |
| B | HOH733 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SEY A 609 |
| Chain | Residue |
| A | PHE82 |
| A | ASP84 |
| A | PRO531 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue SEY A 610 |
| Chain | Residue |
| B | LYS520 |
| B | GLN527 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SEY A 611 |
| Chain | Residue |
| A | LEU83 |
| A | SER119 |
| A | TYR370 |
| A | HOH723 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue ACT A 612 |
| Chain | Residue |
| A | SER114 |
| A | TYR134 |
| A | GLU136 |
| A | TYR144 |
| A | HIS209 |
| A | SER264 |
| A | HIS292 |
| A | LLP318 |
| A | ARG454 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue FMT A 613 |
| Chain | Residue |
| A | ALA291 |
| A | SER294 |
| A | THR315 |
| A | THR316 |
| A | HIS317 |
| A | LLP318 |
| A | SER319 |
| A | LEU320 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue SEY B 601 |
| Chain | Residue |
| B | ALA263 |
| B | TYR266 |
| B | ARG268 |
| B | ASN408 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue SEY B 602 |
| Chain | Residue |
| B | LEU352 |
| B | HOH737 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SEY B 603 |
| Chain | Residue |
| B | ILE155 |
| B | GLN158 |
| B | LEU490 |
| B | SER492 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SEY B 604 |
| Chain | Residue |
| B | GLN158 |
| B | VAL174 |
| B | LYS332 |
| B | GLU341 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue SEY B 605 |
| Chain | Residue |
| B | PHE82 |
| B | ASP84 |
| B | PRO529 |
| B | ILE530 |
| B | PRO531 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SEY B 606 |
| Chain | Residue |
| B | VAL395 |
| B | LEU401 |
| B | GLY404 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SEY B 607 |
| Chain | Residue |
| B | LEU83 |
| B | ALA90 |
| B | SER119 |
| B | TYR370 |
| B | HOH705 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue SEY B 608 |
| Chain | Residue |
| B | GLY140 |
| B | ARG142 |
| B | TYR144 |
| B | GLU426 |
| B | HOH729 |
| B | HOH789 |
| site_id | AE4 |
| Number of Residues | 8 |
| Details | binding site for residue ACT B 609 |
| Chain | Residue |
| B | SER114 |
| B | TYR134 |
| B | TYR144 |
| B | HIS209 |
| B | SER264 |
| B | HIS292 |
| B | LYS318 |
| B | ARG454 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 610 |
| Chain | Residue |
| B | SER180 |
| B | GLY181 |
| B | SER182 |
| B | GLY354 |
| B | TYR134 |
| site_id | AE6 |
| Number of Residues | 9 |
| Details | binding site for residue FMT B 611 |
| Chain | Residue |
| B | ALA291 |
| B | SER294 |
| B | THR314 |
| B | THR315 |
| B | THR316 |
| B | HIS317 |
| B | LYS318 |
| B | SER319 |
| B | LEU320 |
Functional Information from PROSITE/UniProt
| site_id | PS00096 |
| Number of Residues | 17 |
| Details | SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DIvTTTTHKSLrGPRGG |
| Chain | Residue | Details |
| A | ASP310-GLY326 | |
| B | ASP310-GLY326 | |
