6CC9
NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006869 | biological_process | lipid transport |
| A | 0008289 | molecular_function | lipid binding |
| A | 0042157 | biological_process | lipoprotein metabolic process |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0000165 | biological_process | MAPK cascade |
| B | 0001934 | biological_process | positive regulation of protein phosphorylation |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0003925 | molecular_function | G protein activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005741 | cellular_component | mitochondrial outer membrane |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005925 | cellular_component | focal adhesion |
| B | 0007165 | biological_process | signal transduction |
| B | 0007265 | biological_process | Ras protein signal transduction |
| B | 0008283 | biological_process | cell population proliferation |
| B | 0008542 | biological_process | visual learning |
| B | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| B | 0010467 | biological_process | gene expression |
| B | 0010628 | biological_process | positive regulation of gene expression |
| B | 0012505 | cellular_component | endomembrane system |
| B | 0014009 | biological_process | glial cell proliferation |
| B | 0016020 | cellular_component | membrane |
| B | 0016601 | biological_process | Rac protein signal transduction |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019003 | molecular_function | GDP binding |
| B | 0021897 | biological_process | forebrain astrocyte development |
| B | 0030036 | biological_process | actin cytoskeleton organization |
| B | 0030857 | biological_process | negative regulation of epithelial cell differentiation |
| B | 0032228 | biological_process | regulation of synaptic transmission, GABAergic |
| B | 0035022 | biological_process | positive regulation of Rac protein signal transduction |
| B | 0035914 | biological_process | skeletal muscle cell differentiation |
| B | 0043495 | molecular_function | protein-membrane adaptor activity |
| B | 0043524 | biological_process | negative regulation of neuron apoptotic process |
| B | 0044877 | molecular_function | protein-containing complex binding |
| B | 0048169 | biological_process | regulation of long-term neuronal synaptic plasticity |
| B | 0048873 | biological_process | homeostasis of number of cells within a tissue |
| B | 0051146 | biological_process | striated muscle cell differentiation |
| B | 0051402 | biological_process | neuron apoptotic process |
| B | 0060252 | biological_process | positive regulation of glial cell proliferation |
| B | 0060441 | biological_process | epithelial tube branching involved in lung morphogenesis |
| B | 0060509 | biological_process | type I pneumocyte differentiation |
| C | 0005576 | cellular_component | extracellular region |
| C | 0006869 | biological_process | lipid transport |
| C | 0008289 | molecular_function | lipid binding |
| C | 0042157 | biological_process | lipoprotein metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue PCW A 401 |
| Chain | Residue |
| A | TYR349 |
| A | ALA353 |
| B | CYS185 |
| B | PCW213 |
| B | 17F228 |
| C | PCW614 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue PCW A 402 |
| Chain | Residue |
| B | PCW205 |
| B | PCW212 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PCW A 403 |
| Chain | Residue |
| B | GLU3 |
| B | LYS5 |
| B | PCW212 |
| B | PCW218 |
| C | PCW606 |
| A | PHE214 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PCW A 404 |
| Chain | Residue |
| B | ARG73 |
| B | VAL103 |
| B | PCW225 |
| C | PCW626 |
| C | 17F631 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PCW A 405 |
| Chain | Residue |
| B | PCW207 |
| B | PCW209 |
| B | 17F228 |
| C | PCW609 |
| C | PCW614 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PCW A 406 |
| Chain | Residue |
| A | LEU397 |
| A | 17F407 |
| B | LYS184 |
| B | 17F227 |
| B | 17F230 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue 17F A 407 |
| Chain | Residue |
| A | PCW406 |
| B | PCW201 |
| B | PCW205 |
| B | 17F227 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PCW A 408 |
| Chain | Residue |
| A | PCW410 |
| A | PCW411 |
| B | PCW205 |
| C | PCW610 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue PCW A 409 |
| Chain | Residue |
| B | 17F227 |
| C | PCW613 |
| C | PCW619 |
| C | 17F630 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue PCW A 410 |
| Chain | Residue |
| A | PCW408 |
| A | PCW411 |
| C | 17F630 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue PCW A 411 |
| Chain | Residue |
| A | PCW408 |
| A | PCW410 |
| C | PCW616 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue PCW B 201 |
| Chain | Residue |
| A | 17F407 |
| B | LYS182 |
| B | THR183 |
| B | LYS184 |
| B | 17F227 |
| B | 17F228 |
| B | 17F230 |
| B | 17F232 |
| C | PCW623 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue PCW B 202 |
| Chain | Residue |
| B | PCW210 |
| B | PCW214 |
| B | PCW215 |
| B | PCW217 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue PCW B 203 |
| Chain | Residue |
| B | LYS184 |
| B | PCW213 |
| B | 17F228 |
| B | 17F230 |
| B | 17F232 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue PCW B 204 |
| Chain | Residue |
| B | LYS175 |
| B | PCW205 |
| B | PCW208 |
| B | PCW212 |
| B | PCW218 |
| B | PCW222 |
| B | 17F231 |
| C | 17F631 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue PCW B 205 |
| Chain | Residue |
| A | PCW402 |
| A | 17F407 |
| A | PCW408 |
| B | PCW204 |
| B | 17F227 |
| C | PCW610 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for residue PCW B 206 |
| Chain | Residue |
| B | LYS175 |
| B | PCW208 |
| B | PCW211 |
| B | PCW218 |
| B | PCW220 |
| B | PCW222 |
| B | PCW224 |
| B | 17F226 |
| B | 17F232 |
| B | PCW235 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue PCW B 207 |
| Chain | Residue |
| A | PCW405 |
| B | LYS179 |
| B | PCW209 |
| B | PCW216 |
| B | 17F228 |
| B | 17F229 |
| C | PCW601 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue PCW B 208 |
| Chain | Residue |
| B | PCW211 |
| B | PCW218 |
| B | PCW219 |
| B | PCW222 |
| B | 17F231 |
| B | PCW234 |
| B | 17F236 |
| C | PCW617 |
| B | LYS175 |
| B | PCW204 |
| B | PCW206 |
| site_id | AE2 |
| Number of Residues | 9 |
| Details | binding site for residue PCW B 209 |
| Chain | Residue |
| A | PCW405 |
| B | LYS178 |
| B | LYS179 |
| B | PCW207 |
| B | PCW216 |
| B | PCW224 |
| B | 17F228 |
| B | 17F232 |
| C | PCW609 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue PCW B 210 |
| Chain | Residue |
| B | LYS177 |
| B | PCW202 |
| B | PCW214 |
| B | PCW217 |
| B | PCW221 |
| B | 17F226 |
| B | 17F229 |
| site_id | AE4 |
| Number of Residues | 10 |
| Details | binding site for residue PCW B 211 |
| Chain | Residue |
| B | LYS176 |
| B | PCW206 |
| B | PCW208 |
| B | PCW215 |
| B | PCW217 |
| B | PCW224 |
| B | 17F226 |
| B | 17F229 |
| B | 17F236 |
| C | PCW607 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue PCW B 212 |
| Chain | Residue |
| A | PCW402 |
| A | PCW403 |
| B | PCW204 |
| B | 17F231 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue PCW B 213 |
| Chain | Residue |
| A | PCW401 |
| B | LYS184 |
| B | CYS185 |
| B | PCW203 |
| B | 17F228 |
| B | 17F230 |
| B | 17F232 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue PCW B 214 |
| Chain | Residue |
| B | PCW202 |
| B | PCW210 |
| B | PCW217 |
| B | 17F229 |
| C | PCW607 |
| C | PCW615 |
| C | 17F633 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue PCW B 215 |
| Chain | Residue |
| B | LYS176 |
| B | PCW202 |
| B | PCW211 |
| B | PCW217 |
| B | PCW219 |
| B | PCW223 |
| C | PCW608 |
| C | 17F632 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue PCW B 216 |
| Chain | Residue |
| B | LYS177 |
| B | PCW207 |
| B | PCW209 |
| B | PCW224 |
| B | 17F229 |
| C | PCW605 |
| site_id | AF1 |
| Number of Residues | 8 |
| Details | binding site for residue PCW B 217 |
| Chain | Residue |
| B | LYS176 |
| B | PCW202 |
| B | PCW210 |
| B | PCW211 |
| B | PCW214 |
| B | PCW215 |
| B | 17F226 |
| C | PCW615 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue PCW B 218 |
| Chain | Residue |
| A | PCW403 |
| B | PCW204 |
| B | PCW206 |
| B | PCW208 |
| B | PCW219 |
| B | PCW225 |
| B | 17F231 |
| site_id | AF3 |
| Number of Residues | 9 |
| Details | binding site for residue PCW B 219 |
| Chain | Residue |
| B | PCW208 |
| B | PCW215 |
| B | PCW218 |
| B | PCW223 |
| B | PCW225 |
| C | PCW621 |
| C | PCW622 |
| C | PCW626 |
| C | 17F631 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue PCW B 220 |
| Chain | Residue |
| B | LYS175 |
| B | PCW206 |
| B | PCW222 |
| B | 17F232 |
| B | PCW235 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue PCW B 221 |
| Chain | Residue |
| B | LYS177 |
| B | PCW210 |
| B | 17F229 |
| C | PCW601 |
| C | 17F627 |
| site_id | AF6 |
| Number of Residues | 7 |
| Details | binding site for residue PCW B 222 |
| Chain | Residue |
| B | PCW204 |
| B | PCW206 |
| B | PCW208 |
| B | PCW220 |
| B | PCW234 |
| B | PCW235 |
| C | PCW622 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue PCW B 223 |
| Chain | Residue |
| B | PCW215 |
| B | PCW219 |
| C | PCW622 |
| site_id | AF8 |
| Number of Residues | 10 |
| Details | binding site for residue PCW B 224 |
| Chain | Residue |
| B | LYS177 |
| B | LYS178 |
| B | PCW206 |
| B | PCW209 |
| B | PCW211 |
| B | PCW216 |
| B | 17F226 |
| B | 17F229 |
| B | 17F232 |
| C | PCW604 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue PCW B 225 |
| Chain | Residue |
| A | PCW404 |
| B | ASP105 |
| B | PCW218 |
| B | PCW219 |
| C | PCW608 |
| C | PCW626 |
| site_id | AG1 |
| Number of Residues | 13 |
| Details | binding site for residue 17F B 226 |
| Chain | Residue |
| B | LYS176 |
| B | LYS177 |
| B | PCW206 |
| B | PCW210 |
| B | PCW211 |
| B | PCW217 |
| B | PCW224 |
| B | 17F232 |
| C | PCW603 |
| C | PCW607 |
| C | PCW621 |
| C | PCW622 |
| C | 17F628 |
| site_id | AG2 |
| Number of Residues | 9 |
| Details | binding site for residue 17F B 227 |
| Chain | Residue |
| A | PCW406 |
| A | 17F407 |
| A | PCW409 |
| B | LYS184 |
| B | PCW201 |
| B | PCW205 |
| B | 17F230 |
| C | PCW613 |
| C | PCW619 |
| site_id | AG3 |
| Number of Residues | 9 |
| Details | binding site for residue 17F B 228 |
| Chain | Residue |
| A | PCW401 |
| A | PCW405 |
| B | LYS179 |
| B | PCW201 |
| B | PCW203 |
| B | PCW207 |
| B | PCW209 |
| B | PCW213 |
| C | PCW611 |
| site_id | AG4 |
| Number of Residues | 9 |
| Details | binding site for residue 17F B 229 |
| Chain | Residue |
| B | LYS177 |
| B | PCW207 |
| B | PCW210 |
| B | PCW211 |
| B | PCW214 |
| B | PCW216 |
| B | PCW221 |
| B | PCW224 |
| C | PCW615 |
| site_id | AG5 |
| Number of Residues | 7 |
| Details | binding site for residue 17F B 230 |
| Chain | Residue |
| A | PCW406 |
| B | LYS184 |
| B | PCW201 |
| B | PCW203 |
| B | PCW213 |
| B | 17F227 |
| C | PCW619 |
| site_id | AG6 |
| Number of Residues | 6 |
| Details | binding site for residue 17F B 231 |
| Chain | Residue |
| B | LYS104 |
| B | PCW204 |
| B | PCW208 |
| B | PCW212 |
| B | PCW218 |
| C | PCW618 |
| site_id | AG7 |
| Number of Residues | 12 |
| Details | binding site for residue 17F B 232 |
| Chain | Residue |
| B | LYS178 |
| B | SER181 |
| B | LYS182 |
| B | PCW201 |
| B | PCW203 |
| B | PCW206 |
| B | PCW209 |
| B | PCW213 |
| B | PCW220 |
| B | PCW224 |
| B | 17F226 |
| B | PCW233 |
| site_id | AG8 |
| Number of Residues | 6 |
| Details | binding site for residue PCW B 233 |
| Chain | Residue |
| B | 17F232 |
| B | 17F236 |
| C | PCW602 |
| C | PCW603 |
| C | PCW623 |
| C | PCW625 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue PCW B 234 |
| Chain | Residue |
| B | PCW208 |
| B | PCW222 |
| C | PCW602 |
| C | PCW617 |
| site_id | AH1 |
| Number of Residues | 6 |
| Details | binding site for residue PCW B 235 |
| Chain | Residue |
| B | PCW206 |
| B | PCW220 |
| B | PCW222 |
| C | PCW602 |
| C | PCW622 |
| C | PCW623 |
| site_id | AH2 |
| Number of Residues | 7 |
| Details | binding site for residue 17F B 236 |
| Chain | Residue |
| B | PCW208 |
| B | PCW211 |
| B | PCW233 |
| C | PCW602 |
| C | PCW603 |
| C | PCW622 |
| C | 17F628 |
| site_id | AH3 |
| Number of Residues | 20 |
| Details | binding site for residue GNP B 237 |
| Chain | Residue |
| B | VAL12 |
| B | GLY13 |
| B | VAL14 |
| B | GLY15 |
| B | LYS16 |
| B | SER17 |
| B | PHE28 |
| B | VAL29 |
| B | ASP30 |
| B | GLU31 |
| B | TYR32 |
| B | ASP33 |
| B | PRO34 |
| B | ASN116 |
| B | LYS117 |
| B | ASP119 |
| B | LEU120 |
| B | SER145 |
| B | ALA146 |
| B | LYS147 |
| site_id | AH4 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 238 |
| Chain | Residue |
| B | THR35 |
| B | TYR40 |
| B | ASP57 |
| site_id | AH5 |
| Number of Residues | 10 |
| Details | binding site for residue EWS B 239 |
| Chain | Residue |
| B | LYS5 |
| B | LEU6 |
| B | VAL7 |
| B | VAL8 |
| B | ASP54 |
| B | ILE55 |
| B | LEU56 |
| B | TYR71 |
| B | MET72 |
| B | THR74 |
| site_id | AH6 |
| Number of Residues | 3 |
| Details | binding site for residue PCW C 601 |
| Chain | Residue |
| B | PCW207 |
| B | PCW221 |
| C | 17F627 |
| site_id | AH7 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 602 |
| Chain | Residue |
| B | PCW233 |
| B | PCW234 |
| B | PCW235 |
| B | 17F236 |
| site_id | AH8 |
| Number of Residues | 7 |
| Details | binding site for residue PCW C 603 |
| Chain | Residue |
| B | 17F226 |
| B | PCW233 |
| B | 17F236 |
| C | PCW605 |
| C | PCW607 |
| C | 17F628 |
| C | 17F632 |
| site_id | AH9 |
| Number of Residues | 3 |
| Details | binding site for residue PCW C 604 |
| Chain | Residue |
| B | PCW224 |
| C | PCW625 |
| C | 17F627 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue PCW C 605 |
| Chain | Residue |
| B | PCW216 |
| C | PCW603 |
| C | PCW607 |
| C | PCW615 |
| C | 17F629 |
| site_id | AI2 |
| Number of Residues | 2 |
| Details | binding site for residue PCW C 606 |
| Chain | Residue |
| A | PCW403 |
| C | PCW612 |
| site_id | AI3 |
| Number of Residues | 8 |
| Details | binding site for residue PCW C 607 |
| Chain | Residue |
| B | PCW211 |
| B | PCW214 |
| B | 17F226 |
| C | PCW603 |
| C | PCW605 |
| C | PCW615 |
| C | 17F632 |
| C | 17F633 |
| site_id | AI4 |
| Number of Residues | 3 |
| Details | binding site for residue PCW C 608 |
| Chain | Residue |
| B | PCW215 |
| B | PCW225 |
| C | 17F631 |
| site_id | AI5 |
| Number of Residues | 5 |
| Details | binding site for residue PCW C 609 |
| Chain | Residue |
| A | PCW405 |
| B | PCW209 |
| C | PCW614 |
| C | PCW624 |
| C | PCW625 |
| site_id | AI6 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 610 |
| Chain | Residue |
| A | PCW408 |
| B | PCW205 |
| C | PCW616 |
| C | PCW617 |
| site_id | AI7 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 611 |
| Chain | Residue |
| B | 17F228 |
| C | PCW613 |
| C | PCW619 |
| C | PCW623 |
| site_id | AI8 |
| Number of Residues | 2 |
| Details | binding site for residue PCW C 612 |
| Chain | Residue |
| C | PCW606 |
| C | PCW626 |
| site_id | AI9 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 613 |
| Chain | Residue |
| A | PCW409 |
| B | 17F227 |
| C | PCW611 |
| C | PCW619 |
| site_id | AJ1 |
| Number of Residues | 3 |
| Details | binding site for residue PCW C 614 |
| Chain | Residue |
| A | PCW401 |
| A | PCW405 |
| C | PCW609 |
| site_id | AJ2 |
| Number of Residues | 9 |
| Details | binding site for residue PCW C 615 |
| Chain | Residue |
| B | PCW214 |
| B | PCW217 |
| B | 17F229 |
| C | PCW605 |
| C | PCW607 |
| C | 17F627 |
| C | 17F629 |
| C | 17F632 |
| C | 17F633 |
| site_id | AJ3 |
| Number of Residues | 3 |
| Details | binding site for residue PCW C 616 |
| Chain | Residue |
| A | PCW411 |
| C | PCW610 |
| C | PCW617 |
| site_id | AJ4 |
| Number of Residues | 5 |
| Details | binding site for residue PCW C 617 |
| Chain | Residue |
| B | PCW208 |
| B | PCW234 |
| C | PCW610 |
| C | PCW616 |
| C | PCW626 |
| site_id | AJ5 |
| Number of Residues | 3 |
| Details | binding site for residue PCW C 618 |
| Chain | Residue |
| B | 17F231 |
| C | PCW622 |
| C | PCW626 |
| site_id | AJ6 |
| Number of Residues | 5 |
| Details | binding site for residue PCW C 619 |
| Chain | Residue |
| A | PCW409 |
| B | 17F227 |
| B | 17F230 |
| C | PCW611 |
| C | PCW613 |
| site_id | AJ7 |
| Number of Residues | 2 |
| Details | binding site for residue PCW C 620 |
| Chain | Residue |
| C | ALA485 |
| C | 17F633 |
| site_id | AJ8 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 621 |
| Chain | Residue |
| B | PCW219 |
| B | 17F226 |
| C | PCW622 |
| C | 17F632 |
| site_id | AJ9 |
| Number of Residues | 8 |
| Details | binding site for residue PCW C 622 |
| Chain | Residue |
| B | PCW219 |
| B | PCW222 |
| B | PCW223 |
| B | 17F226 |
| B | PCW235 |
| B | 17F236 |
| C | PCW618 |
| C | PCW621 |
| site_id | AK1 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 623 |
| Chain | Residue |
| B | PCW201 |
| B | PCW233 |
| B | PCW235 |
| C | PCW611 |
| site_id | AK2 |
| Number of Residues | 2 |
| Details | binding site for residue PCW C 624 |
| Chain | Residue |
| C | PCW609 |
| C | PCW625 |
| site_id | AK3 |
| Number of Residues | 4 |
| Details | binding site for residue PCW C 625 |
| Chain | Residue |
| B | PCW233 |
| C | PCW604 |
| C | PCW609 |
| C | PCW624 |
| site_id | AK4 |
| Number of Residues | 7 |
| Details | binding site for residue PCW C 626 |
| Chain | Residue |
| A | PCW404 |
| B | PCW219 |
| B | PCW225 |
| C | PCW612 |
| C | PCW617 |
| C | PCW618 |
| C | 17F631 |
| site_id | AK5 |
| Number of Residues | 5 |
| Details | binding site for residue 17F C 627 |
| Chain | Residue |
| B | PCW221 |
| C | PCW601 |
| C | PCW604 |
| C | PCW615 |
| C | 17F629 |
| site_id | AK6 |
| Number of Residues | 4 |
| Details | binding site for residue 17F C 628 |
| Chain | Residue |
| B | 17F226 |
| B | 17F236 |
| C | PCW603 |
| C | 17F632 |
| site_id | AK7 |
| Number of Residues | 5 |
| Details | binding site for residue 17F C 629 |
| Chain | Residue |
| C | VAL474 |
| C | PCW605 |
| C | PCW615 |
| C | 17F627 |
| C | 17F633 |
| site_id | AK8 |
| Number of Residues | 3 |
| Details | binding site for residue 17F C 630 |
| Chain | Residue |
| A | PCW409 |
| A | PCW410 |
| C | LEU595 |
| site_id | AK9 |
| Number of Residues | 5 |
| Details | binding site for residue 17F C 631 |
| Chain | Residue |
| A | PCW404 |
| B | PCW204 |
| B | PCW219 |
| C | PCW608 |
| C | PCW626 |
| site_id | AL1 |
| Number of Residues | 6 |
| Details | binding site for residue 17F C 632 |
| Chain | Residue |
| B | PCW215 |
| C | PCW603 |
| C | PCW607 |
| C | PCW615 |
| C | PCW621 |
| C | 17F628 |
| site_id | AL2 |
| Number of Residues | 5 |
| Details | binding site for residue 17F C 633 |
| Chain | Residue |
| B | PCW214 |
| C | PCW607 |
| C | PCW615 |
| C | PCW620 |
| C | 17F629 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22431598, ECO:0000269|PubMed:22566140 |
| Chain | Residue | Details |
| B | GLY10 | |
| B | VAL29 | |
| B | ALA59 | |
| B | ASN116 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine; in GTPase KRas; alternate => ECO:0000269|Ref.17 |
| Chain | Residue | Details |
| B | MET1 | |
| C | LYS594 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine; in GTPase KRas, N-terminally processed => ECO:0000269|Ref.17 |
| Chain | Residue | Details |
| B | THR2 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:22711838 |
| Chain | Residue | Details |
| B | LYS104 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000305|PubMed:29239724 |
| Chain | Residue | Details |
| B | LYS180 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | LIPID: N6-palmitoyl lysine => ECO:0000269|PubMed:29239724 |
| Chain | Residue | Details |
| B | LYS182 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | LIPID: N6-palmitoyl lysine => ECO:0000305|PubMed:29239724 |
| Chain | Residue | Details |
| B | LYS184 | |
| B | CYS185 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486 |
| Chain | Residue | Details |
| B | THR35 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:30442762 |
| Chain | Residue | Details |
| B | MET170 |
