6CC2

Crystal Structure of CDC45 from Entamoeba histolytica

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000727	biological_process	double-strand break repair via break-induced replication
A	0003682	molecular_function	chromatin binding
A	0003688	molecular_function	DNA replication origin binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005634	cellular_component	nucleus
A	0006260	biological_process	DNA replication
A	0006270	biological_process	DNA replication initiation
A	0031261	cellular_component	DNA replication preinitiation complex
A	0051301	biological_process	cell division
A	1902977	biological_process	mitotic DNA replication preinitiation complex assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue EDO A 601

Chain	Residue
A	ASN198
A	PRO250
A	MSE251
A	LYS320
A	HOH704

---

site_id	AC2
Number of Residues	7
Details	binding site for residue EDO A 602

Chain	Residue
A	TYR462
A	ARG526
A	HOH912
A	CYS420
A	PHE421
A	ASN422
A	ARG428

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO A 603

Chain	Residue
A	MSE508
A	ILE524
A	HIS525
A	ASN528

---

site_id	AC4
Number of Residues	8
Details	binding site for residue EDO A 604

Chain	Residue
A	TYR178
A	ILE217
A	THR221
A	GLU369
A	PRO370
A	ASP371
A	HOH923
A	HOH925

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO A 605

Chain	Residue
A	GLN375
A	EDO608
A	HOH706
A	HOH968

---

site_id	AC6
Number of Residues	4
Details	binding site for residue EDO A 606

Chain	Residue
A	THR479
A	GLU523
A	HIS525
A	HOH890

---

site_id	AC7
Number of Residues	3
Details	binding site for residue EDO A 607

Chain	Residue
A	LEU243
A	ARG263
A	TYR310

---

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO A 608

Chain	Residue
A	TYR130
A	GLN375
A	EDO605
A	HOH714

---

site_id	AC9
Number of Residues	4
Details	binding site for residue EDO A 609

Chain	Residue
A	TYR39
A	GLU47
A	HIS53
A	PHE382

---

site_id	AD1
Number of Residues	2
Details	binding site for residue EDO A 610

Chain	Residue
A	ASP256
A	ARG263

---

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO A 611

Chain	Residue
A	LYS311
A	MSE313
A	LYS318

---

site_id	AD3
Number of Residues	3
Details	binding site for residue EDO A 612

Chain	Residue
A	ARG460
A	LYS463
A	TRP465

---

site_id	AD4
Number of Residues	1
Details	binding site for residue CL A 614

Chain	Residue
A	ASN406

---

site_id	AD5
Number of Residues	2
Details	binding site for residue CL A 615

Chain	Residue
A	ASN336
A	HOH993

---

site_id	AD6
Number of Residues	8
Details	binding site for residue PEG A 616

Chain	Residue
A	ILE413
A	SER417
A	GLY418
A	ASN422
A	ALA424
A	ASN425
A	SER433
A	ASP434

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