Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue BVR A 101 |
| Chain | Residue |
| A | ASP25 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH207 |
| A | HOH220 |
| A | HOH241 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| A | GLY27 |
| B | ASP130 |
| B | ILE147 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | VAL182 |
| B | ILE184 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 102 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH262 |
| B | ARG141 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 201 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 202 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| B | THR112 |
| B | GLU165 |
| B | ALA167 |
| B | GLY168 |
| B | HOH368 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE199 | |
