6C8S
Loganic acid methyltransferase with SAH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0030749 | molecular_function | loganate O-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0035834 | biological_process | indole alkaloid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0030749 | molecular_function | loganate O-methyltransferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0035834 | biological_process | indole alkaloid metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | PRO21 |
| A | GLY140 |
| A | SER141 |
| A | PHE142 |
| A | TYR143 |
| A | SER158 |
| A | TYR159 |
| A | ALA160 |
| A | HOH513 |
| A | HOH522 |
| A | HOH526 |
| A | MET22 |
| A | HOH527 |
| A | HOH573 |
| A | TYR31 |
| A | GLN38 |
| A | GLY77 |
| A | SER79 |
| A | ASN83 |
| A | ASP114 |
| A | HIS115 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for residue SAH B 401 |
| Chain | Residue |
| B | PRO21 |
| B | MET22 |
| B | TYR31 |
| B | GLN38 |
| B | ILE42 |
| B | GLY77 |
| B | CYS78 |
| B | SER79 |
| B | ASN83 |
| B | ASP114 |
| B | HIS115 |
| B | GLY140 |
| B | SER141 |
| B | PHE142 |
| B | TYR143 |
| B | SER158 |
| B | TYR159 |
| B | ALA160 |
| B | HOH529 |
| B | HOH530 |
| B | HOH556 |
| B | HOH560 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:A4GE70 |
| Chain | Residue | Details |
| A | TYR31 | |
| B | TYR31 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29399933, ECO:0007744|PDB:6C8R, ECO:0007744|PDB:6C8S |
| Chain | Residue | Details |
| A | ASN34 | |
| A | GLN316 | |
| B | ASN34 | |
| B | GLY77 | |
| B | ASN83 | |
| B | PHE112 | |
| B | SER141 | |
| B | SER158 | |
| B | TYR159 | |
| B | GLY240 | |
| B | GLN273 | |
| A | GLY77 | |
| B | GLN316 | |
| A | ASN83 | |
| A | PHE112 | |
| A | SER141 | |
| A | SER158 | |
| A | TYR159 | |
| A | GLY240 | |
| A | GLN273 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9FLN8 |
| Chain | Residue | Details |
| A | ASN180 | |
| A | ASP267 | |
| A | PHE269 | |
| B | ASN180 | |
| B | ASP267 | |
| B | PHE269 |
