6C7M

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 19 round 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MPD A 301

Chain	Residue
A	GLN118
A	THR119
A	ASN148
A	GLY150
A	HOH405
A	HOH557
A	HOH676

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MPD A 302

Chain	Residue
A	TYR128
A	ARG202
A	HOH579
A	HOH597
A	TRP50
A	GLY81

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MPD A 303

Chain	Residue
A	ARG191
A	THR195
A	PRO197
A	ASP219

---