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6C6D

20mer crystal structure of CC chemokine 5 (CCL5)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002407biological_processdendritic cell chemotaxis
A0002548biological_processmonocyte chemotaxis
A0002676biological_processregulation of chronic inflammatory response
A0004435molecular_functionphosphatidylinositol phospholipase C activity
A0004672molecular_functionprotein kinase activity
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0006816biological_processcalcium ion transport
A0006874biological_processintracellular calcium ion homeostasis
A0006887biological_processexocytosis
A0006935biological_processchemotaxis
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007159biological_processleukocyte cell-cell adhesion
A0007186biological_processG protein-coupled receptor signaling pathway
A0007267biological_processcell-cell signaling
A0008009molecular_functionchemokine activity
A0009615biological_processresponse to virus
A0009636biological_processresponse to toxic substance
A0010536biological_processpositive regulation of activation of Janus kinase activity
A0010759biological_processpositive regulation of macrophage chemotaxis
A0010820biological_processpositive regulation of T cell chemotaxis
A0014911biological_processpositive regulation of smooth muscle cell migration
A0016004molecular_functionphospholipase activator activity
A0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
A0030335biological_processpositive regulation of cell migration
A0031328biological_processpositive regulation of cellular biosynthetic process
A0031584biological_processactivation of phospholipase D activity
A0031726molecular_functionCCR1 chemokine receptor binding
A0031729molecular_functionCCR4 chemokine receptor binding
A0031730molecular_functionCCR5 chemokine receptor binding
A0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
A0034097biological_processresponse to cytokine
A0034112biological_processpositive regulation of homotypic cell-cell adhesion
A0034612biological_processresponse to tumor necrosis factor
A0042056molecular_functionchemoattractant activity
A0042102biological_processpositive regulation of T cell proliferation
A0042119biological_processneutrophil activation
A0042327biological_processpositive regulation of phosphorylation
A0042379molecular_functionchemokine receptor binding
A0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043922biological_processnegative regulation by host of viral transcription
A0044344biological_processcellular response to fibroblast growth factor stimulus
A0045070biological_processpositive regulation of viral genome replication
A0045071biological_processnegative regulation of viral genome replication
A0045089biological_processpositive regulation of innate immune response
A0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
A0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
A0045785biological_processpositive regulation of cell adhesion
A0045948biological_processpositive regulation of translational initiation
A0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
A0046817molecular_functionchemokine receptor antagonist activity
A0048020molecular_functionCCR chemokine receptor binding
A0048245biological_processeosinophil chemotaxis
A0048246biological_processmacrophage chemotaxis
A0048661biological_processpositive regulation of smooth muscle cell proliferation
A0050673biological_processepithelial cell proliferation
A0050679biological_processpositive regulation of epithelial cell proliferation
A0050796biological_processregulation of insulin secretion
A0050863biological_processregulation of T cell activation
A0050918biological_processpositive chemotaxis
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0051928biological_processpositive regulation of calcium ion transport
A0060326biological_processcell chemotaxis
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0070098biological_processchemokine-mediated signaling pathway
A0070100biological_processnegative regulation of chemokine-mediated signaling pathway
A0070233biological_processnegative regulation of T cell apoptotic process
A0070234biological_processpositive regulation of T cell apoptotic process
A0071346biological_processcellular response to type II interferon
A0071347biological_processcellular response to interleukin-1
A0071356biological_processcellular response to tumor necrosis factor
A0090026biological_processpositive regulation of monocyte chemotaxis
A0098586biological_processcellular response to virus
A2000110biological_processnegative regulation of macrophage apoptotic process
A2000406biological_processpositive regulation of T cell migration
A2000503biological_processpositive regulation of natural killer cell chemotaxis
B0002407biological_processdendritic cell chemotaxis
B0002548biological_processmonocyte chemotaxis
B0002676biological_processregulation of chronic inflammatory response
B0004435molecular_functionphosphatidylinositol phospholipase C activity
B0004672molecular_functionprotein kinase activity
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0006816biological_processcalcium ion transport
B0006874biological_processintracellular calcium ion homeostasis
B0006887biological_processexocytosis
B0006935biological_processchemotaxis
B0006954biological_processinflammatory response
B0006955biological_processimmune response
B0007159biological_processleukocyte cell-cell adhesion
B0007186biological_processG protein-coupled receptor signaling pathway
B0007267biological_processcell-cell signaling
B0008009molecular_functionchemokine activity
B0009615biological_processresponse to virus
B0009636biological_processresponse to toxic substance
B0010536biological_processpositive regulation of activation of Janus kinase activity
B0010759biological_processpositive regulation of macrophage chemotaxis
B0010820biological_processpositive regulation of T cell chemotaxis
B0014911biological_processpositive regulation of smooth muscle cell migration
B0016004molecular_functionphospholipase activator activity
B0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
B0030335biological_processpositive regulation of cell migration
B0031328biological_processpositive regulation of cellular biosynthetic process
B0031584biological_processactivation of phospholipase D activity
B0031726molecular_functionCCR1 chemokine receptor binding
B0031729molecular_functionCCR4 chemokine receptor binding
B0031730molecular_functionCCR5 chemokine receptor binding
B0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
B0034097biological_processresponse to cytokine
B0034112biological_processpositive regulation of homotypic cell-cell adhesion
B0034612biological_processresponse to tumor necrosis factor
B0042056molecular_functionchemoattractant activity
B0042102biological_processpositive regulation of T cell proliferation
B0042119biological_processneutrophil activation
B0042327biological_processpositive regulation of phosphorylation
B0042379molecular_functionchemokine receptor binding
B0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043922biological_processnegative regulation by host of viral transcription
B0044344biological_processcellular response to fibroblast growth factor stimulus
B0045070biological_processpositive regulation of viral genome replication
B0045071biological_processnegative regulation of viral genome replication
B0045089biological_processpositive regulation of innate immune response
B0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
B0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
B0045785biological_processpositive regulation of cell adhesion
B0045948biological_processpositive regulation of translational initiation
B0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
B0046817molecular_functionchemokine receptor antagonist activity
B0048020molecular_functionCCR chemokine receptor binding
B0048245biological_processeosinophil chemotaxis
B0048246biological_processmacrophage chemotaxis
B0048661biological_processpositive regulation of smooth muscle cell proliferation
B0050673biological_processepithelial cell proliferation
B0050679biological_processpositive regulation of epithelial cell proliferation
B0050796biological_processregulation of insulin secretion
B0050863biological_processregulation of T cell activation
B0050918biological_processpositive chemotaxis
B0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B0051928biological_processpositive regulation of calcium ion transport
B0060326biological_processcell chemotaxis
B0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
B0070098biological_processchemokine-mediated signaling pathway
B0070100biological_processnegative regulation of chemokine-mediated signaling pathway
B0070233biological_processnegative regulation of T cell apoptotic process
B0070234biological_processpositive regulation of T cell apoptotic process
B0071346biological_processcellular response to type II interferon
B0071347biological_processcellular response to interleukin-1
B0071356biological_processcellular response to tumor necrosis factor
B0090026biological_processpositive regulation of monocyte chemotaxis
B0098586biological_processcellular response to virus
B2000110biological_processnegative regulation of macrophage apoptotic process
B2000406biological_processpositive regulation of T cell migration
B2000503biological_processpositive regulation of natural killer cell chemotaxis
C0002407biological_processdendritic cell chemotaxis
C0002548biological_processmonocyte chemotaxis
C0002676biological_processregulation of chronic inflammatory response
C0004435molecular_functionphosphatidylinositol phospholipase C activity
C0004672molecular_functionprotein kinase activity
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005737cellular_componentcytoplasm
C0006816biological_processcalcium ion transport
C0006874biological_processintracellular calcium ion homeostasis
C0006887biological_processexocytosis
C0006935biological_processchemotaxis
C0006954biological_processinflammatory response
C0006955biological_processimmune response
C0007159biological_processleukocyte cell-cell adhesion
C0007186biological_processG protein-coupled receptor signaling pathway
C0007267biological_processcell-cell signaling
C0008009molecular_functionchemokine activity
C0009615biological_processresponse to virus
C0009636biological_processresponse to toxic substance
C0010536biological_processpositive regulation of activation of Janus kinase activity
C0010759biological_processpositive regulation of macrophage chemotaxis
C0010820biological_processpositive regulation of T cell chemotaxis
C0014911biological_processpositive regulation of smooth muscle cell migration
C0016004molecular_functionphospholipase activator activity
C0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
C0030335biological_processpositive regulation of cell migration
C0031328biological_processpositive regulation of cellular biosynthetic process
C0031584biological_processactivation of phospholipase D activity
C0031726molecular_functionCCR1 chemokine receptor binding
C0031729molecular_functionCCR4 chemokine receptor binding
C0031730molecular_functionCCR5 chemokine receptor binding
C0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
C0034097biological_processresponse to cytokine
C0034112biological_processpositive regulation of homotypic cell-cell adhesion
C0034612biological_processresponse to tumor necrosis factor
C0042056molecular_functionchemoattractant activity
C0042102biological_processpositive regulation of T cell proliferation
C0042119biological_processneutrophil activation
C0042327biological_processpositive regulation of phosphorylation
C0042379molecular_functionchemokine receptor binding
C0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043922biological_processnegative regulation by host of viral transcription
C0044344biological_processcellular response to fibroblast growth factor stimulus
C0045070biological_processpositive regulation of viral genome replication
C0045071biological_processnegative regulation of viral genome replication
C0045089biological_processpositive regulation of innate immune response
C0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
C0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
C0045785biological_processpositive regulation of cell adhesion
C0045948biological_processpositive regulation of translational initiation
C0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
C0046817molecular_functionchemokine receptor antagonist activity
C0048020molecular_functionCCR chemokine receptor binding
C0048245biological_processeosinophil chemotaxis
C0048246biological_processmacrophage chemotaxis
C0048661biological_processpositive regulation of smooth muscle cell proliferation
C0050673biological_processepithelial cell proliferation
C0050679biological_processpositive regulation of epithelial cell proliferation
C0050796biological_processregulation of insulin secretion
C0050863biological_processregulation of T cell activation
C0050918biological_processpositive chemotaxis
C0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C0051928biological_processpositive regulation of calcium ion transport
C0060326biological_processcell chemotaxis
C0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
C0070098biological_processchemokine-mediated signaling pathway
C0070100biological_processnegative regulation of chemokine-mediated signaling pathway
C0070233biological_processnegative regulation of T cell apoptotic process
C0070234biological_processpositive regulation of T cell apoptotic process
C0071346biological_processcellular response to type II interferon
C0071347biological_processcellular response to interleukin-1
C0071356biological_processcellular response to tumor necrosis factor
C0090026biological_processpositive regulation of monocyte chemotaxis
C0098586biological_processcellular response to virus
C2000110biological_processnegative regulation of macrophage apoptotic process
C2000406biological_processpositive regulation of T cell migration
C2000503biological_processpositive regulation of natural killer cell chemotaxis
D0002407biological_processdendritic cell chemotaxis
D0002548biological_processmonocyte chemotaxis
D0002676biological_processregulation of chronic inflammatory response
D0004435molecular_functionphosphatidylinositol phospholipase C activity
D0004672molecular_functionprotein kinase activity
D0005125molecular_functioncytokine activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005737cellular_componentcytoplasm
D0006816biological_processcalcium ion transport
D0006874biological_processintracellular calcium ion homeostasis
D0006887biological_processexocytosis
D0006935biological_processchemotaxis
D0006954biological_processinflammatory response
D0006955biological_processimmune response
D0007159biological_processleukocyte cell-cell adhesion
D0007186biological_processG protein-coupled receptor signaling pathway
D0007267biological_processcell-cell signaling
D0008009molecular_functionchemokine activity
D0009615biological_processresponse to virus
D0009636biological_processresponse to toxic substance
D0010536biological_processpositive regulation of activation of Janus kinase activity
D0010759biological_processpositive regulation of macrophage chemotaxis
D0010820biological_processpositive regulation of T cell chemotaxis
D0014911biological_processpositive regulation of smooth muscle cell migration
D0016004molecular_functionphospholipase activator activity
D0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
D0030335biological_processpositive regulation of cell migration
D0031328biological_processpositive regulation of cellular biosynthetic process
D0031584biological_processactivation of phospholipase D activity
D0031726molecular_functionCCR1 chemokine receptor binding
D0031729molecular_functionCCR4 chemokine receptor binding
D0031730molecular_functionCCR5 chemokine receptor binding
D0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
D0034097biological_processresponse to cytokine
D0034112biological_processpositive regulation of homotypic cell-cell adhesion
D0034612biological_processresponse to tumor necrosis factor
D0042056molecular_functionchemoattractant activity
D0042102biological_processpositive regulation of T cell proliferation
D0042119biological_processneutrophil activation
D0042327biological_processpositive regulation of phosphorylation
D0042379molecular_functionchemokine receptor binding
D0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043922biological_processnegative regulation by host of viral transcription
D0044344biological_processcellular response to fibroblast growth factor stimulus
D0045070biological_processpositive regulation of viral genome replication
D0045071biological_processnegative regulation of viral genome replication
D0045089biological_processpositive regulation of innate immune response
D0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
D0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
D0045785biological_processpositive regulation of cell adhesion
D0045948biological_processpositive regulation of translational initiation
D0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
D0046817molecular_functionchemokine receptor antagonist activity
D0048020molecular_functionCCR chemokine receptor binding
D0048245biological_processeosinophil chemotaxis
D0048246biological_processmacrophage chemotaxis
D0048661biological_processpositive regulation of smooth muscle cell proliferation
D0050673biological_processepithelial cell proliferation
D0050679biological_processpositive regulation of epithelial cell proliferation
D0050796biological_processregulation of insulin secretion
D0050863biological_processregulation of T cell activation
D0050918biological_processpositive chemotaxis
D0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
D0051928biological_processpositive regulation of calcium ion transport
D0060326biological_processcell chemotaxis
D0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
D0070098biological_processchemokine-mediated signaling pathway
D0070100biological_processnegative regulation of chemokine-mediated signaling pathway
D0070233biological_processnegative regulation of T cell apoptotic process
D0070234biological_processpositive regulation of T cell apoptotic process
D0071346biological_processcellular response to type II interferon
D0071347biological_processcellular response to interleukin-1
D0071356biological_processcellular response to tumor necrosis factor
D0090026biological_processpositive regulation of monocyte chemotaxis
D0098586biological_processcellular response to virus
D2000110biological_processnegative regulation of macrophage apoptotic process
D2000406biological_processpositive regulation of T cell migration
D2000503biological_processpositive regulation of natural killer cell chemotaxis
E0002407biological_processdendritic cell chemotaxis
E0002548biological_processmonocyte chemotaxis
E0002676biological_processregulation of chronic inflammatory response
E0004435molecular_functionphosphatidylinositol phospholipase C activity
E0004672molecular_functionprotein kinase activity
E0005125molecular_functioncytokine activity
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005737cellular_componentcytoplasm
E0006816biological_processcalcium ion transport
E0006874biological_processintracellular calcium ion homeostasis
E0006887biological_processexocytosis
E0006935biological_processchemotaxis
E0006954biological_processinflammatory response
E0006955biological_processimmune response
E0007159biological_processleukocyte cell-cell adhesion
E0007186biological_processG protein-coupled receptor signaling pathway
E0007267biological_processcell-cell signaling
E0008009molecular_functionchemokine activity
E0009615biological_processresponse to virus
E0009636biological_processresponse to toxic substance
E0010536biological_processpositive regulation of activation of Janus kinase activity
E0010759biological_processpositive regulation of macrophage chemotaxis
E0010820biological_processpositive regulation of T cell chemotaxis
E0014911biological_processpositive regulation of smooth muscle cell migration
E0016004molecular_functionphospholipase activator activity
E0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
E0030335biological_processpositive regulation of cell migration
E0031328biological_processpositive regulation of cellular biosynthetic process
E0031584biological_processactivation of phospholipase D activity
E0031726molecular_functionCCR1 chemokine receptor binding
E0031729molecular_functionCCR4 chemokine receptor binding
E0031730molecular_functionCCR5 chemokine receptor binding
E0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
E0034097biological_processresponse to cytokine
E0034112biological_processpositive regulation of homotypic cell-cell adhesion
E0034612biological_processresponse to tumor necrosis factor
E0042056molecular_functionchemoattractant activity
E0042102biological_processpositive regulation of T cell proliferation
E0042119biological_processneutrophil activation
E0042327biological_processpositive regulation of phosphorylation
E0042379molecular_functionchemokine receptor binding
E0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
E0042802molecular_functionidentical protein binding
E0042803molecular_functionprotein homodimerization activity
E0043922biological_processnegative regulation by host of viral transcription
E0044344biological_processcellular response to fibroblast growth factor stimulus
E0045070biological_processpositive regulation of viral genome replication
E0045071biological_processnegative regulation of viral genome replication
E0045089biological_processpositive regulation of innate immune response
E0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
E0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
E0045785biological_processpositive regulation of cell adhesion
E0045948biological_processpositive regulation of translational initiation
E0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
E0046817molecular_functionchemokine receptor antagonist activity
E0048020molecular_functionCCR chemokine receptor binding
E0048245biological_processeosinophil chemotaxis
E0048246biological_processmacrophage chemotaxis
E0048661biological_processpositive regulation of smooth muscle cell proliferation
E0050673biological_processepithelial cell proliferation
E0050679biological_processpositive regulation of epithelial cell proliferation
E0050796biological_processregulation of insulin secretion
E0050863biological_processregulation of T cell activation
E0050918biological_processpositive chemotaxis
E0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
E0051928biological_processpositive regulation of calcium ion transport
E0060326biological_processcell chemotaxis
E0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
E0070098biological_processchemokine-mediated signaling pathway
E0070100biological_processnegative regulation of chemokine-mediated signaling pathway
E0070233biological_processnegative regulation of T cell apoptotic process
E0070234biological_processpositive regulation of T cell apoptotic process
E0071346biological_processcellular response to type II interferon
E0071347biological_processcellular response to interleukin-1
E0071356biological_processcellular response to tumor necrosis factor
E0090026biological_processpositive regulation of monocyte chemotaxis
E0098586biological_processcellular response to virus
E2000110biological_processnegative regulation of macrophage apoptotic process
E2000406biological_processpositive regulation of T cell migration
E2000503biological_processpositive regulation of natural killer cell chemotaxis
F0002407biological_processdendritic cell chemotaxis
F0002548biological_processmonocyte chemotaxis
F0002676biological_processregulation of chronic inflammatory response
F0004435molecular_functionphosphatidylinositol phospholipase C activity
F0004672molecular_functionprotein kinase activity
F0005125molecular_functioncytokine activity
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005737cellular_componentcytoplasm
F0006816biological_processcalcium ion transport
F0006874biological_processintracellular calcium ion homeostasis
F0006887biological_processexocytosis
F0006935biological_processchemotaxis
F0006954biological_processinflammatory response
F0006955biological_processimmune response
F0007159biological_processleukocyte cell-cell adhesion
F0007186biological_processG protein-coupled receptor signaling pathway
F0007267biological_processcell-cell signaling
F0008009molecular_functionchemokine activity
F0009615biological_processresponse to virus
F0009636biological_processresponse to toxic substance
F0010536biological_processpositive regulation of activation of Janus kinase activity
F0010759biological_processpositive regulation of macrophage chemotaxis
F0010820biological_processpositive regulation of T cell chemotaxis
F0014911biological_processpositive regulation of smooth muscle cell migration
F0016004molecular_functionphospholipase activator activity
F0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
F0030335biological_processpositive regulation of cell migration
F0031328biological_processpositive regulation of cellular biosynthetic process
F0031584biological_processactivation of phospholipase D activity
F0031726molecular_functionCCR1 chemokine receptor binding
F0031729molecular_functionCCR4 chemokine receptor binding
F0031730molecular_functionCCR5 chemokine receptor binding
F0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
F0034097biological_processresponse to cytokine
F0034112biological_processpositive regulation of homotypic cell-cell adhesion
F0034612biological_processresponse to tumor necrosis factor
F0042056molecular_functionchemoattractant activity
F0042102biological_processpositive regulation of T cell proliferation
F0042119biological_processneutrophil activation
F0042327biological_processpositive regulation of phosphorylation
F0042379molecular_functionchemokine receptor binding
F0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
F0042802molecular_functionidentical protein binding
F0042803molecular_functionprotein homodimerization activity
F0043922biological_processnegative regulation by host of viral transcription
F0044344biological_processcellular response to fibroblast growth factor stimulus
F0045070biological_processpositive regulation of viral genome replication
F0045071biological_processnegative regulation of viral genome replication
F0045089biological_processpositive regulation of innate immune response
F0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
F0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
F0045785biological_processpositive regulation of cell adhesion
F0045948biological_processpositive regulation of translational initiation
F0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
F0046817molecular_functionchemokine receptor antagonist activity
F0048020molecular_functionCCR chemokine receptor binding
F0048245biological_processeosinophil chemotaxis
F0048246biological_processmacrophage chemotaxis
F0048661biological_processpositive regulation of smooth muscle cell proliferation
F0050673biological_processepithelial cell proliferation
F0050679biological_processpositive regulation of epithelial cell proliferation
F0050796biological_processregulation of insulin secretion
F0050863biological_processregulation of T cell activation
F0050918biological_processpositive chemotaxis
F0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
F0051928biological_processpositive regulation of calcium ion transport
F0060326biological_processcell chemotaxis
F0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
F0070098biological_processchemokine-mediated signaling pathway
F0070100biological_processnegative regulation of chemokine-mediated signaling pathway
F0070233biological_processnegative regulation of T cell apoptotic process
F0070234biological_processpositive regulation of T cell apoptotic process
F0071346biological_processcellular response to type II interferon
F0071347biological_processcellular response to interleukin-1
F0071356biological_processcellular response to tumor necrosis factor
F0090026biological_processpositive regulation of monocyte chemotaxis
F0098586biological_processcellular response to virus
F2000110biological_processnegative regulation of macrophage apoptotic process
F2000406biological_processpositive regulation of T cell migration
F2000503biological_processpositive regulation of natural killer cell chemotaxis
G0002407biological_processdendritic cell chemotaxis
G0002548biological_processmonocyte chemotaxis
G0002676biological_processregulation of chronic inflammatory response
G0004435molecular_functionphosphatidylinositol phospholipase C activity
G0004672molecular_functionprotein kinase activity
G0005125molecular_functioncytokine activity
G0005515molecular_functionprotein binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005737cellular_componentcytoplasm
G0006816biological_processcalcium ion transport
G0006874biological_processintracellular calcium ion homeostasis
G0006887biological_processexocytosis
G0006935biological_processchemotaxis
G0006954biological_processinflammatory response
G0006955biological_processimmune response
G0007159biological_processleukocyte cell-cell adhesion
G0007186biological_processG protein-coupled receptor signaling pathway
G0007267biological_processcell-cell signaling
G0008009molecular_functionchemokine activity
G0009615biological_processresponse to virus
G0009636biological_processresponse to toxic substance
G0010536biological_processpositive regulation of activation of Janus kinase activity
G0010759biological_processpositive regulation of macrophage chemotaxis
G0010820biological_processpositive regulation of T cell chemotaxis
G0014911biological_processpositive regulation of smooth muscle cell migration
G0016004molecular_functionphospholipase activator activity
G0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
G0030335biological_processpositive regulation of cell migration
G0031328biological_processpositive regulation of cellular biosynthetic process
G0031584biological_processactivation of phospholipase D activity
G0031726molecular_functionCCR1 chemokine receptor binding
G0031729molecular_functionCCR4 chemokine receptor binding
G0031730molecular_functionCCR5 chemokine receptor binding
G0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
G0034097biological_processresponse to cytokine
G0034112biological_processpositive regulation of homotypic cell-cell adhesion
G0034612biological_processresponse to tumor necrosis factor
G0042056molecular_functionchemoattractant activity
G0042102biological_processpositive regulation of T cell proliferation
G0042119biological_processneutrophil activation
G0042327biological_processpositive regulation of phosphorylation
G0042379molecular_functionchemokine receptor binding
G0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
G0042802molecular_functionidentical protein binding
G0042803molecular_functionprotein homodimerization activity
G0043922biological_processnegative regulation by host of viral transcription
G0044344biological_processcellular response to fibroblast growth factor stimulus
G0045070biological_processpositive regulation of viral genome replication
G0045071biological_processnegative regulation of viral genome replication
G0045089biological_processpositive regulation of innate immune response
G0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
G0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
G0045785biological_processpositive regulation of cell adhesion
G0045948biological_processpositive regulation of translational initiation
G0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
G0046817molecular_functionchemokine receptor antagonist activity
G0048020molecular_functionCCR chemokine receptor binding
G0048245biological_processeosinophil chemotaxis
G0048246biological_processmacrophage chemotaxis
G0048661biological_processpositive regulation of smooth muscle cell proliferation
G0050673biological_processepithelial cell proliferation
G0050679biological_processpositive regulation of epithelial cell proliferation
G0050796biological_processregulation of insulin secretion
G0050863biological_processregulation of T cell activation
G0050918biological_processpositive chemotaxis
G0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
G0051928biological_processpositive regulation of calcium ion transport
G0060326biological_processcell chemotaxis
G0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
G0070098biological_processchemokine-mediated signaling pathway
G0070100biological_processnegative regulation of chemokine-mediated signaling pathway
G0070233biological_processnegative regulation of T cell apoptotic process
G0070234biological_processpositive regulation of T cell apoptotic process
G0071346biological_processcellular response to type II interferon
G0071347biological_processcellular response to interleukin-1
G0071356biological_processcellular response to tumor necrosis factor
G0090026biological_processpositive regulation of monocyte chemotaxis
G0098586biological_processcellular response to virus
G2000110biological_processnegative regulation of macrophage apoptotic process
G2000406biological_processpositive regulation of T cell migration
G2000503biological_processpositive regulation of natural killer cell chemotaxis
H0002407biological_processdendritic cell chemotaxis
H0002548biological_processmonocyte chemotaxis
H0002676biological_processregulation of chronic inflammatory response
H0004435molecular_functionphosphatidylinositol phospholipase C activity
H0004672molecular_functionprotein kinase activity
H0005125molecular_functioncytokine activity
H0005515molecular_functionprotein binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005737cellular_componentcytoplasm
H0006816biological_processcalcium ion transport
H0006874biological_processintracellular calcium ion homeostasis
H0006887biological_processexocytosis
H0006935biological_processchemotaxis
H0006954biological_processinflammatory response
H0006955biological_processimmune response
H0007159biological_processleukocyte cell-cell adhesion
H0007186biological_processG protein-coupled receptor signaling pathway
H0007267biological_processcell-cell signaling
H0008009molecular_functionchemokine activity
H0009615biological_processresponse to virus
H0009636biological_processresponse to toxic substance
H0010536biological_processpositive regulation of activation of Janus kinase activity
H0010759biological_processpositive regulation of macrophage chemotaxis
H0010820biological_processpositive regulation of T cell chemotaxis
H0014911biological_processpositive regulation of smooth muscle cell migration
H0016004molecular_functionphospholipase activator activity
H0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
H0030335biological_processpositive regulation of cell migration
H0031328biological_processpositive regulation of cellular biosynthetic process
H0031584biological_processactivation of phospholipase D activity
H0031726molecular_functionCCR1 chemokine receptor binding
H0031729molecular_functionCCR4 chemokine receptor binding
H0031730molecular_functionCCR5 chemokine receptor binding
H0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
H0034097biological_processresponse to cytokine
H0034112biological_processpositive regulation of homotypic cell-cell adhesion
H0034612biological_processresponse to tumor necrosis factor
H0042056molecular_functionchemoattractant activity
H0042102biological_processpositive regulation of T cell proliferation
H0042119biological_processneutrophil activation
H0042327biological_processpositive regulation of phosphorylation
H0042379molecular_functionchemokine receptor binding
H0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0043922biological_processnegative regulation by host of viral transcription
H0044344biological_processcellular response to fibroblast growth factor stimulus
H0045070biological_processpositive regulation of viral genome replication
H0045071biological_processnegative regulation of viral genome replication
H0045089biological_processpositive regulation of innate immune response
H0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
H0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
H0045785biological_processpositive regulation of cell adhesion
H0045948biological_processpositive regulation of translational initiation
H0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
H0046817molecular_functionchemokine receptor antagonist activity
H0048020molecular_functionCCR chemokine receptor binding
H0048245biological_processeosinophil chemotaxis
H0048246biological_processmacrophage chemotaxis
H0048661biological_processpositive regulation of smooth muscle cell proliferation
H0050673biological_processepithelial cell proliferation
H0050679biological_processpositive regulation of epithelial cell proliferation
H0050796biological_processregulation of insulin secretion
H0050863biological_processregulation of T cell activation
H0050918biological_processpositive chemotaxis
H0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
H0051928biological_processpositive regulation of calcium ion transport
H0060326biological_processcell chemotaxis
H0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
H0070098biological_processchemokine-mediated signaling pathway
H0070100biological_processnegative regulation of chemokine-mediated signaling pathway
H0070233biological_processnegative regulation of T cell apoptotic process
H0070234biological_processpositive regulation of T cell apoptotic process
H0071346biological_processcellular response to type II interferon
H0071347biological_processcellular response to interleukin-1
H0071356biological_processcellular response to tumor necrosis factor
H0090026biological_processpositive regulation of monocyte chemotaxis
H0098586biological_processcellular response to virus
H2000110biological_processnegative regulation of macrophage apoptotic process
H2000406biological_processpositive regulation of T cell migration
H2000503biological_processpositive regulation of natural killer cell chemotaxis
I0002407biological_processdendritic cell chemotaxis
I0002548biological_processmonocyte chemotaxis
I0002676biological_processregulation of chronic inflammatory response
I0004435molecular_functionphosphatidylinositol phospholipase C activity
I0004672molecular_functionprotein kinase activity
I0005125molecular_functioncytokine activity
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005737cellular_componentcytoplasm
I0006816biological_processcalcium ion transport
I0006874biological_processintracellular calcium ion homeostasis
I0006887biological_processexocytosis
I0006935biological_processchemotaxis
I0006954biological_processinflammatory response
I0006955biological_processimmune response
I0007159biological_processleukocyte cell-cell adhesion
I0007186biological_processG protein-coupled receptor signaling pathway
I0007267biological_processcell-cell signaling
I0008009molecular_functionchemokine activity
I0009615biological_processresponse to virus
I0009636biological_processresponse to toxic substance
I0010536biological_processpositive regulation of activation of Janus kinase activity
I0010759biological_processpositive regulation of macrophage chemotaxis
I0010820biological_processpositive regulation of T cell chemotaxis
I0014911biological_processpositive regulation of smooth muscle cell migration
I0016004molecular_functionphospholipase activator activity
I0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
I0030335biological_processpositive regulation of cell migration
I0031328biological_processpositive regulation of cellular biosynthetic process
I0031584biological_processactivation of phospholipase D activity
I0031726molecular_functionCCR1 chemokine receptor binding
I0031729molecular_functionCCR4 chemokine receptor binding
I0031730molecular_functionCCR5 chemokine receptor binding
I0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
I0034097biological_processresponse to cytokine
I0034112biological_processpositive regulation of homotypic cell-cell adhesion
I0034612biological_processresponse to tumor necrosis factor
I0042056molecular_functionchemoattractant activity
I0042102biological_processpositive regulation of T cell proliferation
I0042119biological_processneutrophil activation
I0042327biological_processpositive regulation of phosphorylation
I0042379molecular_functionchemokine receptor binding
I0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
I0042802molecular_functionidentical protein binding
I0042803molecular_functionprotein homodimerization activity
I0043922biological_processnegative regulation by host of viral transcription
I0044344biological_processcellular response to fibroblast growth factor stimulus
I0045070biological_processpositive regulation of viral genome replication
I0045071biological_processnegative regulation of viral genome replication
I0045089biological_processpositive regulation of innate immune response
I0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
I0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
I0045785biological_processpositive regulation of cell adhesion
I0045948biological_processpositive regulation of translational initiation
I0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
I0046817molecular_functionchemokine receptor antagonist activity
I0048020molecular_functionCCR chemokine receptor binding
I0048245biological_processeosinophil chemotaxis
I0048246biological_processmacrophage chemotaxis
I0048661biological_processpositive regulation of smooth muscle cell proliferation
I0050673biological_processepithelial cell proliferation
I0050679biological_processpositive regulation of epithelial cell proliferation
I0050796biological_processregulation of insulin secretion
I0050863biological_processregulation of T cell activation
I0050918biological_processpositive chemotaxis
I0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
I0051928biological_processpositive regulation of calcium ion transport
I0060326biological_processcell chemotaxis
I0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
I0070098biological_processchemokine-mediated signaling pathway
I0070100biological_processnegative regulation of chemokine-mediated signaling pathway
I0070233biological_processnegative regulation of T cell apoptotic process
I0070234biological_processpositive regulation of T cell apoptotic process
I0071346biological_processcellular response to type II interferon
I0071347biological_processcellular response to interleukin-1
I0071356biological_processcellular response to tumor necrosis factor
I0090026biological_processpositive regulation of monocyte chemotaxis
I0098586biological_processcellular response to virus
I2000110biological_processnegative regulation of macrophage apoptotic process
I2000406biological_processpositive regulation of T cell migration
I2000503biological_processpositive regulation of natural killer cell chemotaxis
J0002407biological_processdendritic cell chemotaxis
J0002548biological_processmonocyte chemotaxis
J0002676biological_processregulation of chronic inflammatory response
J0004435molecular_functionphosphatidylinositol phospholipase C activity
J0004672molecular_functionprotein kinase activity
J0005125molecular_functioncytokine activity
J0005515molecular_functionprotein binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005737cellular_componentcytoplasm
J0006816biological_processcalcium ion transport
J0006874biological_processintracellular calcium ion homeostasis
J0006887biological_processexocytosis
J0006935biological_processchemotaxis
J0006954biological_processinflammatory response
J0006955biological_processimmune response
J0007159biological_processleukocyte cell-cell adhesion
J0007186biological_processG protein-coupled receptor signaling pathway
J0007267biological_processcell-cell signaling
J0008009molecular_functionchemokine activity
J0009615biological_processresponse to virus
J0009636biological_processresponse to toxic substance
J0010536biological_processpositive regulation of activation of Janus kinase activity
J0010759biological_processpositive regulation of macrophage chemotaxis
J0010820biological_processpositive regulation of T cell chemotaxis
J0014911biological_processpositive regulation of smooth muscle cell migration
J0016004molecular_functionphospholipase activator activity
J0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
J0030335biological_processpositive regulation of cell migration
J0031328biological_processpositive regulation of cellular biosynthetic process
J0031584biological_processactivation of phospholipase D activity
J0031726molecular_functionCCR1 chemokine receptor binding
J0031729molecular_functionCCR4 chemokine receptor binding
J0031730molecular_functionCCR5 chemokine receptor binding
J0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
J0034097biological_processresponse to cytokine
J0034112biological_processpositive regulation of homotypic cell-cell adhesion
J0034612biological_processresponse to tumor necrosis factor
J0042056molecular_functionchemoattractant activity
J0042102biological_processpositive regulation of T cell proliferation
J0042119biological_processneutrophil activation
J0042327biological_processpositive regulation of phosphorylation
J0042379molecular_functionchemokine receptor binding
J0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
J0042802molecular_functionidentical protein binding
J0042803molecular_functionprotein homodimerization activity
J0043922biological_processnegative regulation by host of viral transcription
J0044344biological_processcellular response to fibroblast growth factor stimulus
J0045070biological_processpositive regulation of viral genome replication
J0045071biological_processnegative regulation of viral genome replication
J0045089biological_processpositive regulation of innate immune response
J0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
J0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
J0045785biological_processpositive regulation of cell adhesion
J0045948biological_processpositive regulation of translational initiation
J0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
J0046817molecular_functionchemokine receptor antagonist activity
J0048020molecular_functionCCR chemokine receptor binding
J0048245biological_processeosinophil chemotaxis
J0048246biological_processmacrophage chemotaxis
J0048661biological_processpositive regulation of smooth muscle cell proliferation
J0050673biological_processepithelial cell proliferation
J0050679biological_processpositive regulation of epithelial cell proliferation
J0050796biological_processregulation of insulin secretion
J0050863biological_processregulation of T cell activation
J0050918biological_processpositive chemotaxis
J0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
J0051928biological_processpositive regulation of calcium ion transport
J0060326biological_processcell chemotaxis
J0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
J0070098biological_processchemokine-mediated signaling pathway
J0070100biological_processnegative regulation of chemokine-mediated signaling pathway
J0070233biological_processnegative regulation of T cell apoptotic process
J0070234biological_processpositive regulation of T cell apoptotic process
J0071346biological_processcellular response to type II interferon
J0071347biological_processcellular response to interleukin-1
J0071356biological_processcellular response to tumor necrosis factor
J0090026biological_processpositive regulation of monocyte chemotaxis
J0098586biological_processcellular response to virus
J2000110biological_processnegative regulation of macrophage apoptotic process
J2000406biological_processpositive regulation of T cell migration
J2000503biological_processpositive regulation of natural killer cell chemotaxis
K0002407biological_processdendritic cell chemotaxis
K0002548biological_processmonocyte chemotaxis
K0002676biological_processregulation of chronic inflammatory response
K0004435molecular_functionphosphatidylinositol phospholipase C activity
K0004672molecular_functionprotein kinase activity
K0005125molecular_functioncytokine activity
K0005515molecular_functionprotein binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005737cellular_componentcytoplasm
K0006816biological_processcalcium ion transport
K0006874biological_processintracellular calcium ion homeostasis
K0006887biological_processexocytosis
K0006935biological_processchemotaxis
K0006954biological_processinflammatory response
K0006955biological_processimmune response
K0007159biological_processleukocyte cell-cell adhesion
K0007186biological_processG protein-coupled receptor signaling pathway
K0007267biological_processcell-cell signaling
K0008009molecular_functionchemokine activity
K0009615biological_processresponse to virus
K0009636biological_processresponse to toxic substance
K0010536biological_processpositive regulation of activation of Janus kinase activity
K0010759biological_processpositive regulation of macrophage chemotaxis
K0010820biological_processpositive regulation of T cell chemotaxis
K0014911biological_processpositive regulation of smooth muscle cell migration
K0016004molecular_functionphospholipase activator activity
K0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
K0030335biological_processpositive regulation of cell migration
K0031328biological_processpositive regulation of cellular biosynthetic process
K0031584biological_processactivation of phospholipase D activity
K0031726molecular_functionCCR1 chemokine receptor binding
K0031729molecular_functionCCR4 chemokine receptor binding
K0031730molecular_functionCCR5 chemokine receptor binding
K0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
K0034097biological_processresponse to cytokine
K0034112biological_processpositive regulation of homotypic cell-cell adhesion
K0034612biological_processresponse to tumor necrosis factor
K0042056molecular_functionchemoattractant activity
K0042102biological_processpositive regulation of T cell proliferation
K0042119biological_processneutrophil activation
K0042327biological_processpositive regulation of phosphorylation
K0042379molecular_functionchemokine receptor binding
K0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
K0042802molecular_functionidentical protein binding
K0042803molecular_functionprotein homodimerization activity
K0043922biological_processnegative regulation by host of viral transcription
K0044344biological_processcellular response to fibroblast growth factor stimulus
K0045070biological_processpositive regulation of viral genome replication
K0045071biological_processnegative regulation of viral genome replication
K0045089biological_processpositive regulation of innate immune response
K0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
K0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
K0045785biological_processpositive regulation of cell adhesion
K0045948biological_processpositive regulation of translational initiation
K0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
K0046817molecular_functionchemokine receptor antagonist activity
K0048020molecular_functionCCR chemokine receptor binding
K0048245biological_processeosinophil chemotaxis
K0048246biological_processmacrophage chemotaxis
K0048661biological_processpositive regulation of smooth muscle cell proliferation
K0050673biological_processepithelial cell proliferation
K0050679biological_processpositive regulation of epithelial cell proliferation
K0050796biological_processregulation of insulin secretion
K0050863biological_processregulation of T cell activation
K0050918biological_processpositive chemotaxis
K0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
K0051928biological_processpositive regulation of calcium ion transport
K0060326biological_processcell chemotaxis
K0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
K0070098biological_processchemokine-mediated signaling pathway
K0070100biological_processnegative regulation of chemokine-mediated signaling pathway
K0070233biological_processnegative regulation of T cell apoptotic process
K0070234biological_processpositive regulation of T cell apoptotic process
K0071346biological_processcellular response to type II interferon
K0071347biological_processcellular response to interleukin-1
K0071356biological_processcellular response to tumor necrosis factor
K0090026biological_processpositive regulation of monocyte chemotaxis
K0098586biological_processcellular response to virus
K2000110biological_processnegative regulation of macrophage apoptotic process
K2000406biological_processpositive regulation of T cell migration
K2000503biological_processpositive regulation of natural killer cell chemotaxis
L0002407biological_processdendritic cell chemotaxis
L0002548biological_processmonocyte chemotaxis
L0002676biological_processregulation of chronic inflammatory response
L0004435molecular_functionphosphatidylinositol phospholipase C activity
L0004672molecular_functionprotein kinase activity
L0005125molecular_functioncytokine activity
L0005515molecular_functionprotein binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005737cellular_componentcytoplasm
L0006816biological_processcalcium ion transport
L0006874biological_processintracellular calcium ion homeostasis
L0006887biological_processexocytosis
L0006935biological_processchemotaxis
L0006954biological_processinflammatory response
L0006955biological_processimmune response
L0007159biological_processleukocyte cell-cell adhesion
L0007186biological_processG protein-coupled receptor signaling pathway
L0007267biological_processcell-cell signaling
L0008009molecular_functionchemokine activity
L0009615biological_processresponse to virus
L0009636biological_processresponse to toxic substance
L0010536biological_processpositive regulation of activation of Janus kinase activity
L0010759biological_processpositive regulation of macrophage chemotaxis
L0010820biological_processpositive regulation of T cell chemotaxis
L0014911biological_processpositive regulation of smooth muscle cell migration
L0016004molecular_functionphospholipase activator activity
L0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
L0030335biological_processpositive regulation of cell migration
L0031328biological_processpositive regulation of cellular biosynthetic process
L0031584biological_processactivation of phospholipase D activity
L0031726molecular_functionCCR1 chemokine receptor binding
L0031729molecular_functionCCR4 chemokine receptor binding
L0031730molecular_functionCCR5 chemokine receptor binding
L0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
L0034097biological_processresponse to cytokine
L0034112biological_processpositive regulation of homotypic cell-cell adhesion
L0034612biological_processresponse to tumor necrosis factor
L0042056molecular_functionchemoattractant activity
L0042102biological_processpositive regulation of T cell proliferation
L0042119biological_processneutrophil activation
L0042327biological_processpositive regulation of phosphorylation
L0042379molecular_functionchemokine receptor binding
L0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
L0042802molecular_functionidentical protein binding
L0042803molecular_functionprotein homodimerization activity
L0043922biological_processnegative regulation by host of viral transcription
L0044344biological_processcellular response to fibroblast growth factor stimulus
L0045070biological_processpositive regulation of viral genome replication
L0045071biological_processnegative regulation of viral genome replication
L0045089biological_processpositive regulation of innate immune response
L0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
L0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
L0045785biological_processpositive regulation of cell adhesion
L0045948biological_processpositive regulation of translational initiation
L0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
L0046817molecular_functionchemokine receptor antagonist activity
L0048020molecular_functionCCR chemokine receptor binding
L0048245biological_processeosinophil chemotaxis
L0048246biological_processmacrophage chemotaxis
L0048661biological_processpositive regulation of smooth muscle cell proliferation
L0050673biological_processepithelial cell proliferation
L0050679biological_processpositive regulation of epithelial cell proliferation
L0050796biological_processregulation of insulin secretion
L0050863biological_processregulation of T cell activation
L0050918biological_processpositive chemotaxis
L0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
L0051928biological_processpositive regulation of calcium ion transport
L0060326biological_processcell chemotaxis
L0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
L0070098biological_processchemokine-mediated signaling pathway
L0070100biological_processnegative regulation of chemokine-mediated signaling pathway
L0070233biological_processnegative regulation of T cell apoptotic process
L0070234biological_processpositive regulation of T cell apoptotic process
L0071346biological_processcellular response to type II interferon
L0071347biological_processcellular response to interleukin-1
L0071356biological_processcellular response to tumor necrosis factor
L0090026biological_processpositive regulation of monocyte chemotaxis
L0098586biological_processcellular response to virus
L2000110biological_processnegative regulation of macrophage apoptotic process
L2000406biological_processpositive regulation of T cell migration
L2000503biological_processpositive regulation of natural killer cell chemotaxis
M0002407biological_processdendritic cell chemotaxis
M0002548biological_processmonocyte chemotaxis
M0002676biological_processregulation of chronic inflammatory response
M0004435molecular_functionphosphatidylinositol phospholipase C activity
M0004672molecular_functionprotein kinase activity
M0005125molecular_functioncytokine activity
M0005515molecular_functionprotein binding
M0005576cellular_componentextracellular region
M0005615cellular_componentextracellular space
M0005737cellular_componentcytoplasm
M0006816biological_processcalcium ion transport
M0006874biological_processintracellular calcium ion homeostasis
M0006887biological_processexocytosis
M0006935biological_processchemotaxis
M0006954biological_processinflammatory response
M0006955biological_processimmune response
M0007159biological_processleukocyte cell-cell adhesion
M0007186biological_processG protein-coupled receptor signaling pathway
M0007267biological_processcell-cell signaling
M0008009molecular_functionchemokine activity
M0009615biological_processresponse to virus
M0009636biological_processresponse to toxic substance
M0010536biological_processpositive regulation of activation of Janus kinase activity
M0010759biological_processpositive regulation of macrophage chemotaxis
M0010820biological_processpositive regulation of T cell chemotaxis
M0014911biological_processpositive regulation of smooth muscle cell migration
M0016004molecular_functionphospholipase activator activity
M0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
M0030335biological_processpositive regulation of cell migration
M0031328biological_processpositive regulation of cellular biosynthetic process
M0031584biological_processactivation of phospholipase D activity
M0031726molecular_functionCCR1 chemokine receptor binding
M0031729molecular_functionCCR4 chemokine receptor binding
M0031730molecular_functionCCR5 chemokine receptor binding
M0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
M0034097biological_processresponse to cytokine
M0034112biological_processpositive regulation of homotypic cell-cell adhesion
M0034612biological_processresponse to tumor necrosis factor
M0042056molecular_functionchemoattractant activity
M0042102biological_processpositive regulation of T cell proliferation
M0042119biological_processneutrophil activation
M0042327biological_processpositive regulation of phosphorylation
M0042379molecular_functionchemokine receptor binding
M0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
M0042802molecular_functionidentical protein binding
M0042803molecular_functionprotein homodimerization activity
M0043922biological_processnegative regulation by host of viral transcription
M0044344biological_processcellular response to fibroblast growth factor stimulus
M0045070biological_processpositive regulation of viral genome replication
M0045071biological_processnegative regulation of viral genome replication
M0045089biological_processpositive regulation of innate immune response
M0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
M0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
M0045785biological_processpositive regulation of cell adhesion
M0045948biological_processpositive regulation of translational initiation
M0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
M0046817molecular_functionchemokine receptor antagonist activity
M0048020molecular_functionCCR chemokine receptor binding
M0048245biological_processeosinophil chemotaxis
M0048246biological_processmacrophage chemotaxis
M0048661biological_processpositive regulation of smooth muscle cell proliferation
M0050673biological_processepithelial cell proliferation
M0050679biological_processpositive regulation of epithelial cell proliferation
M0050796biological_processregulation of insulin secretion
M0050863biological_processregulation of T cell activation
M0050918biological_processpositive chemotaxis
M0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
M0051928biological_processpositive regulation of calcium ion transport
M0060326biological_processcell chemotaxis
M0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
M0070098biological_processchemokine-mediated signaling pathway
M0070100biological_processnegative regulation of chemokine-mediated signaling pathway
M0070233biological_processnegative regulation of T cell apoptotic process
M0070234biological_processpositive regulation of T cell apoptotic process
M0071346biological_processcellular response to type II interferon
M0071347biological_processcellular response to interleukin-1
M0071356biological_processcellular response to tumor necrosis factor
M0090026biological_processpositive regulation of monocyte chemotaxis
M0098586biological_processcellular response to virus
M2000110biological_processnegative regulation of macrophage apoptotic process
M2000406biological_processpositive regulation of T cell migration
M2000503biological_processpositive regulation of natural killer cell chemotaxis
N0002407biological_processdendritic cell chemotaxis
N0002548biological_processmonocyte chemotaxis
N0002676biological_processregulation of chronic inflammatory response
N0004435molecular_functionphosphatidylinositol phospholipase C activity
N0004672molecular_functionprotein kinase activity
N0005125molecular_functioncytokine activity
N0005515molecular_functionprotein binding
N0005576cellular_componentextracellular region
N0005615cellular_componentextracellular space
N0005737cellular_componentcytoplasm
N0006816biological_processcalcium ion transport
N0006874biological_processintracellular calcium ion homeostasis
N0006887biological_processexocytosis
N0006935biological_processchemotaxis
N0006954biological_processinflammatory response
N0006955biological_processimmune response
N0007159biological_processleukocyte cell-cell adhesion
N0007186biological_processG protein-coupled receptor signaling pathway
N0007267biological_processcell-cell signaling
N0008009molecular_functionchemokine activity
N0009615biological_processresponse to virus
N0009636biological_processresponse to toxic substance
N0010536biological_processpositive regulation of activation of Janus kinase activity
N0010759biological_processpositive regulation of macrophage chemotaxis
N0010820biological_processpositive regulation of T cell chemotaxis
N0014911biological_processpositive regulation of smooth muscle cell migration
N0016004molecular_functionphospholipase activator activity
N0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
N0030335biological_processpositive regulation of cell migration
N0031328biological_processpositive regulation of cellular biosynthetic process
N0031584biological_processactivation of phospholipase D activity
N0031726molecular_functionCCR1 chemokine receptor binding
N0031729molecular_functionCCR4 chemokine receptor binding
N0031730molecular_functionCCR5 chemokine receptor binding
N0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
N0034097biological_processresponse to cytokine
N0034112biological_processpositive regulation of homotypic cell-cell adhesion
N0034612biological_processresponse to tumor necrosis factor
N0042056molecular_functionchemoattractant activity
N0042102biological_processpositive regulation of T cell proliferation
N0042119biological_processneutrophil activation
N0042327biological_processpositive regulation of phosphorylation
N0042379molecular_functionchemokine receptor binding
N0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
N0042802molecular_functionidentical protein binding
N0042803molecular_functionprotein homodimerization activity
N0043922biological_processnegative regulation by host of viral transcription
N0044344biological_processcellular response to fibroblast growth factor stimulus
N0045070biological_processpositive regulation of viral genome replication
N0045071biological_processnegative regulation of viral genome replication
N0045089biological_processpositive regulation of innate immune response
N0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
N0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
N0045785biological_processpositive regulation of cell adhesion
N0045948biological_processpositive regulation of translational initiation
N0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
N0046817molecular_functionchemokine receptor antagonist activity
N0048020molecular_functionCCR chemokine receptor binding
N0048245biological_processeosinophil chemotaxis
N0048246biological_processmacrophage chemotaxis
N0048661biological_processpositive regulation of smooth muscle cell proliferation
N0050673biological_processepithelial cell proliferation
N0050679biological_processpositive regulation of epithelial cell proliferation
N0050796biological_processregulation of insulin secretion
N0050863biological_processregulation of T cell activation
N0050918biological_processpositive chemotaxis
N0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
N0051928biological_processpositive regulation of calcium ion transport
N0060326biological_processcell chemotaxis
N0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
N0070098biological_processchemokine-mediated signaling pathway
N0070100biological_processnegative regulation of chemokine-mediated signaling pathway
N0070233biological_processnegative regulation of T cell apoptotic process
N0070234biological_processpositive regulation of T cell apoptotic process
N0071346biological_processcellular response to type II interferon
N0071347biological_processcellular response to interleukin-1
N0071356biological_processcellular response to tumor necrosis factor
N0090026biological_processpositive regulation of monocyte chemotaxis
N0098586biological_processcellular response to virus
N2000110biological_processnegative regulation of macrophage apoptotic process
N2000406biological_processpositive regulation of T cell migration
N2000503biological_processpositive regulation of natural killer cell chemotaxis
O0002407biological_processdendritic cell chemotaxis
O0002548biological_processmonocyte chemotaxis
O0002676biological_processregulation of chronic inflammatory response
O0004435molecular_functionphosphatidylinositol phospholipase C activity
O0004672molecular_functionprotein kinase activity
O0005125molecular_functioncytokine activity
O0005515molecular_functionprotein binding
O0005576cellular_componentextracellular region
O0005615cellular_componentextracellular space
O0005737cellular_componentcytoplasm
O0006816biological_processcalcium ion transport
O0006874biological_processintracellular calcium ion homeostasis
O0006887biological_processexocytosis
O0006935biological_processchemotaxis
O0006954biological_processinflammatory response
O0006955biological_processimmune response
O0007159biological_processleukocyte cell-cell adhesion
O0007186biological_processG protein-coupled receptor signaling pathway
O0007267biological_processcell-cell signaling
O0008009molecular_functionchemokine activity
O0009615biological_processresponse to virus
O0009636biological_processresponse to toxic substance
O0010536biological_processpositive regulation of activation of Janus kinase activity
O0010759biological_processpositive regulation of macrophage chemotaxis
O0010820biological_processpositive regulation of T cell chemotaxis
O0014911biological_processpositive regulation of smooth muscle cell migration
O0016004molecular_functionphospholipase activator activity
O0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
O0030335biological_processpositive regulation of cell migration
O0031328biological_processpositive regulation of cellular biosynthetic process
O0031584biological_processactivation of phospholipase D activity
O0031726molecular_functionCCR1 chemokine receptor binding
O0031729molecular_functionCCR4 chemokine receptor binding
O0031730molecular_functionCCR5 chemokine receptor binding
O0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
O0034097biological_processresponse to cytokine
O0034112biological_processpositive regulation of homotypic cell-cell adhesion
O0034612biological_processresponse to tumor necrosis factor
O0042056molecular_functionchemoattractant activity
O0042102biological_processpositive regulation of T cell proliferation
O0042119biological_processneutrophil activation
O0042327biological_processpositive regulation of phosphorylation
O0042379molecular_functionchemokine receptor binding
O0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
O0042802molecular_functionidentical protein binding
O0042803molecular_functionprotein homodimerization activity
O0043922biological_processnegative regulation by host of viral transcription
O0044344biological_processcellular response to fibroblast growth factor stimulus
O0045070biological_processpositive regulation of viral genome replication
O0045071biological_processnegative regulation of viral genome replication
O0045089biological_processpositive regulation of innate immune response
O0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
O0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
O0045785biological_processpositive regulation of cell adhesion
O0045948biological_processpositive regulation of translational initiation
O0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
O0046817molecular_functionchemokine receptor antagonist activity
O0048020molecular_functionCCR chemokine receptor binding
O0048245biological_processeosinophil chemotaxis
O0048246biological_processmacrophage chemotaxis
O0048661biological_processpositive regulation of smooth muscle cell proliferation
O0050673biological_processepithelial cell proliferation
O0050679biological_processpositive regulation of epithelial cell proliferation
O0050796biological_processregulation of insulin secretion
O0050863biological_processregulation of T cell activation
O0050918biological_processpositive chemotaxis
O0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
O0051928biological_processpositive regulation of calcium ion transport
O0060326biological_processcell chemotaxis
O0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
O0070098biological_processchemokine-mediated signaling pathway
O0070100biological_processnegative regulation of chemokine-mediated signaling pathway
O0070233biological_processnegative regulation of T cell apoptotic process
O0070234biological_processpositive regulation of T cell apoptotic process
O0071346biological_processcellular response to type II interferon
O0071347biological_processcellular response to interleukin-1
O0071356biological_processcellular response to tumor necrosis factor
O0090026biological_processpositive regulation of monocyte chemotaxis
O0098586biological_processcellular response to virus
O2000110biological_processnegative regulation of macrophage apoptotic process
O2000406biological_processpositive regulation of T cell migration
O2000503biological_processpositive regulation of natural killer cell chemotaxis
P0002407biological_processdendritic cell chemotaxis
P0002548biological_processmonocyte chemotaxis
P0002676biological_processregulation of chronic inflammatory response
P0004435molecular_functionphosphatidylinositol phospholipase C activity
P0004672molecular_functionprotein kinase activity
P0005125molecular_functioncytokine activity
P0005515molecular_functionprotein binding
P0005576cellular_componentextracellular region
P0005615cellular_componentextracellular space
P0005737cellular_componentcytoplasm
P0006816biological_processcalcium ion transport
P0006874biological_processintracellular calcium ion homeostasis
P0006887biological_processexocytosis
P0006935biological_processchemotaxis
P0006954biological_processinflammatory response
P0006955biological_processimmune response
P0007159biological_processleukocyte cell-cell adhesion
P0007186biological_processG protein-coupled receptor signaling pathway
P0007267biological_processcell-cell signaling
P0008009molecular_functionchemokine activity
P0009615biological_processresponse to virus
P0009636biological_processresponse to toxic substance
P0010536biological_processpositive regulation of activation of Janus kinase activity
P0010759biological_processpositive regulation of macrophage chemotaxis
P0010820biological_processpositive regulation of T cell chemotaxis
P0014911biological_processpositive regulation of smooth muscle cell migration
P0016004molecular_functionphospholipase activator activity
P0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
P0030335biological_processpositive regulation of cell migration
P0031328biological_processpositive regulation of cellular biosynthetic process
P0031584biological_processactivation of phospholipase D activity
P0031726molecular_functionCCR1 chemokine receptor binding
P0031729molecular_functionCCR4 chemokine receptor binding
P0031730molecular_functionCCR5 chemokine receptor binding
P0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
P0034097biological_processresponse to cytokine
P0034112biological_processpositive regulation of homotypic cell-cell adhesion
P0034612biological_processresponse to tumor necrosis factor
P0042056molecular_functionchemoattractant activity
P0042102biological_processpositive regulation of T cell proliferation
P0042119biological_processneutrophil activation
P0042327biological_processpositive regulation of phosphorylation
P0042379molecular_functionchemokine receptor binding
P0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
P0042802molecular_functionidentical protein binding
P0042803molecular_functionprotein homodimerization activity
P0043922biological_processnegative regulation by host of viral transcription
P0044344biological_processcellular response to fibroblast growth factor stimulus
P0045070biological_processpositive regulation of viral genome replication
P0045071biological_processnegative regulation of viral genome replication
P0045089biological_processpositive regulation of innate immune response
P0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
P0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
P0045785biological_processpositive regulation of cell adhesion
P0045948biological_processpositive regulation of translational initiation
P0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
P0046817molecular_functionchemokine receptor antagonist activity
P0048020molecular_functionCCR chemokine receptor binding
P0048245biological_processeosinophil chemotaxis
P0048246biological_processmacrophage chemotaxis
P0048661biological_processpositive regulation of smooth muscle cell proliferation
P0050673biological_processepithelial cell proliferation
P0050679biological_processpositive regulation of epithelial cell proliferation
P0050796biological_processregulation of insulin secretion
P0050863biological_processregulation of T cell activation
P0050918biological_processpositive chemotaxis
P0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
P0051928biological_processpositive regulation of calcium ion transport
P0060326biological_processcell chemotaxis
P0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
P0070098biological_processchemokine-mediated signaling pathway
P0070100biological_processnegative regulation of chemokine-mediated signaling pathway
P0070233biological_processnegative regulation of T cell apoptotic process
P0070234biological_processpositive regulation of T cell apoptotic process
P0071346biological_processcellular response to type II interferon
P0071347biological_processcellular response to interleukin-1
P0071356biological_processcellular response to tumor necrosis factor
P0090026biological_processpositive regulation of monocyte chemotaxis
P0098586biological_processcellular response to virus
P2000110biological_processnegative regulation of macrophage apoptotic process
P2000406biological_processpositive regulation of T cell migration
P2000503biological_processpositive regulation of natural killer cell chemotaxis
Q0002407biological_processdendritic cell chemotaxis
Q0002548biological_processmonocyte chemotaxis
Q0002676biological_processregulation of chronic inflammatory response
Q0004435molecular_functionphosphatidylinositol phospholipase C activity
Q0004672molecular_functionprotein kinase activity
Q0005125molecular_functioncytokine activity
Q0005515molecular_functionprotein binding
Q0005576cellular_componentextracellular region
Q0005615cellular_componentextracellular space
Q0005737cellular_componentcytoplasm
Q0006816biological_processcalcium ion transport
Q0006874biological_processintracellular calcium ion homeostasis
Q0006887biological_processexocytosis
Q0006935biological_processchemotaxis
Q0006954biological_processinflammatory response
Q0006955biological_processimmune response
Q0007159biological_processleukocyte cell-cell adhesion
Q0007186biological_processG protein-coupled receptor signaling pathway
Q0007267biological_processcell-cell signaling
Q0008009molecular_functionchemokine activity
Q0009615biological_processresponse to virus
Q0009636biological_processresponse to toxic substance
Q0010536biological_processpositive regulation of activation of Janus kinase activity
Q0010759biological_processpositive regulation of macrophage chemotaxis
Q0010820biological_processpositive regulation of T cell chemotaxis
Q0014911biological_processpositive regulation of smooth muscle cell migration
Q0016004molecular_functionphospholipase activator activity
Q0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
Q0030335biological_processpositive regulation of cell migration
Q0031328biological_processpositive regulation of cellular biosynthetic process
Q0031584biological_processactivation of phospholipase D activity
Q0031726molecular_functionCCR1 chemokine receptor binding
Q0031729molecular_functionCCR4 chemokine receptor binding
Q0031730molecular_functionCCR5 chemokine receptor binding
Q0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
Q0034097biological_processresponse to cytokine
Q0034112biological_processpositive regulation of homotypic cell-cell adhesion
Q0034612biological_processresponse to tumor necrosis factor
Q0042056molecular_functionchemoattractant activity
Q0042102biological_processpositive regulation of T cell proliferation
Q0042119biological_processneutrophil activation
Q0042327biological_processpositive regulation of phosphorylation
Q0042379molecular_functionchemokine receptor binding
Q0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
Q0042802molecular_functionidentical protein binding
Q0042803molecular_functionprotein homodimerization activity
Q0043922biological_processnegative regulation by host of viral transcription
Q0044344biological_processcellular response to fibroblast growth factor stimulus
Q0045070biological_processpositive regulation of viral genome replication
Q0045071biological_processnegative regulation of viral genome replication
Q0045089biological_processpositive regulation of innate immune response
Q0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
Q0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
Q0045785biological_processpositive regulation of cell adhesion
Q0045948biological_processpositive regulation of translational initiation
Q0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
Q0046817molecular_functionchemokine receptor antagonist activity
Q0048020molecular_functionCCR chemokine receptor binding
Q0048245biological_processeosinophil chemotaxis
Q0048246biological_processmacrophage chemotaxis
Q0048661biological_processpositive regulation of smooth muscle cell proliferation
Q0050673biological_processepithelial cell proliferation
Q0050679biological_processpositive regulation of epithelial cell proliferation
Q0050796biological_processregulation of insulin secretion
Q0050863biological_processregulation of T cell activation
Q0050918biological_processpositive chemotaxis
Q0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Q0051928biological_processpositive regulation of calcium ion transport
Q0060326biological_processcell chemotaxis
Q0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
Q0070098biological_processchemokine-mediated signaling pathway
Q0070100biological_processnegative regulation of chemokine-mediated signaling pathway
Q0070233biological_processnegative regulation of T cell apoptotic process
Q0070234biological_processpositive regulation of T cell apoptotic process
Q0071346biological_processcellular response to type II interferon
Q0071347biological_processcellular response to interleukin-1
Q0071356biological_processcellular response to tumor necrosis factor
Q0090026biological_processpositive regulation of monocyte chemotaxis
Q0098586biological_processcellular response to virus
Q2000110biological_processnegative regulation of macrophage apoptotic process
Q2000406biological_processpositive regulation of T cell migration
Q2000503biological_processpositive regulation of natural killer cell chemotaxis
R0002407biological_processdendritic cell chemotaxis
R0002548biological_processmonocyte chemotaxis
R0002676biological_processregulation of chronic inflammatory response
R0004435molecular_functionphosphatidylinositol phospholipase C activity
R0004672molecular_functionprotein kinase activity
R0005125molecular_functioncytokine activity
R0005515molecular_functionprotein binding
R0005576cellular_componentextracellular region
R0005615cellular_componentextracellular space
R0005737cellular_componentcytoplasm
R0006816biological_processcalcium ion transport
R0006874biological_processintracellular calcium ion homeostasis
R0006887biological_processexocytosis
R0006935biological_processchemotaxis
R0006954biological_processinflammatory response
R0006955biological_processimmune response
R0007159biological_processleukocyte cell-cell adhesion
R0007186biological_processG protein-coupled receptor signaling pathway
R0007267biological_processcell-cell signaling
R0008009molecular_functionchemokine activity
R0009615biological_processresponse to virus
R0009636biological_processresponse to toxic substance
R0010536biological_processpositive regulation of activation of Janus kinase activity
R0010759biological_processpositive regulation of macrophage chemotaxis
R0010820biological_processpositive regulation of T cell chemotaxis
R0014911biological_processpositive regulation of smooth muscle cell migration
R0016004molecular_functionphospholipase activator activity
R0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
R0030335biological_processpositive regulation of cell migration
R0031328biological_processpositive regulation of cellular biosynthetic process
R0031584biological_processactivation of phospholipase D activity
R0031726molecular_functionCCR1 chemokine receptor binding
R0031729molecular_functionCCR4 chemokine receptor binding
R0031730molecular_functionCCR5 chemokine receptor binding
R0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
R0034097biological_processresponse to cytokine
R0034112biological_processpositive regulation of homotypic cell-cell adhesion
R0034612biological_processresponse to tumor necrosis factor
R0042056molecular_functionchemoattractant activity
R0042102biological_processpositive regulation of T cell proliferation
R0042119biological_processneutrophil activation
R0042327biological_processpositive regulation of phosphorylation
R0042379molecular_functionchemokine receptor binding
R0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
R0042802molecular_functionidentical protein binding
R0042803molecular_functionprotein homodimerization activity
R0043922biological_processnegative regulation by host of viral transcription
R0044344biological_processcellular response to fibroblast growth factor stimulus
R0045070biological_processpositive regulation of viral genome replication
R0045071biological_processnegative regulation of viral genome replication
R0045089biological_processpositive regulation of innate immune response
R0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
R0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
R0045785biological_processpositive regulation of cell adhesion
R0045948biological_processpositive regulation of translational initiation
R0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
R0046817molecular_functionchemokine receptor antagonist activity
R0048020molecular_functionCCR chemokine receptor binding
R0048245biological_processeosinophil chemotaxis
R0048246biological_processmacrophage chemotaxis
R0048661biological_processpositive regulation of smooth muscle cell proliferation
R0050673biological_processepithelial cell proliferation
R0050679biological_processpositive regulation of epithelial cell proliferation
R0050796biological_processregulation of insulin secretion
R0050863biological_processregulation of T cell activation
R0050918biological_processpositive chemotaxis
R0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
R0051928biological_processpositive regulation of calcium ion transport
R0060326biological_processcell chemotaxis
R0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
R0070098biological_processchemokine-mediated signaling pathway
R0070100biological_processnegative regulation of chemokine-mediated signaling pathway
R0070233biological_processnegative regulation of T cell apoptotic process
R0070234biological_processpositive regulation of T cell apoptotic process
R0071346biological_processcellular response to type II interferon
R0071347biological_processcellular response to interleukin-1
R0071356biological_processcellular response to tumor necrosis factor
R0090026biological_processpositive regulation of monocyte chemotaxis
R0098586biological_processcellular response to virus
R2000110biological_processnegative regulation of macrophage apoptotic process
R2000406biological_processpositive regulation of T cell migration
R2000503biological_processpositive regulation of natural killer cell chemotaxis
S0002407biological_processdendritic cell chemotaxis
S0002548biological_processmonocyte chemotaxis
S0002676biological_processregulation of chronic inflammatory response
S0004435molecular_functionphosphatidylinositol phospholipase C activity
S0004672molecular_functionprotein kinase activity
S0005125molecular_functioncytokine activity
S0005515molecular_functionprotein binding
S0005576cellular_componentextracellular region
S0005615cellular_componentextracellular space
S0005737cellular_componentcytoplasm
S0006816biological_processcalcium ion transport
S0006874biological_processintracellular calcium ion homeostasis
S0006887biological_processexocytosis
S0006935biological_processchemotaxis
S0006954biological_processinflammatory response
S0006955biological_processimmune response
S0007159biological_processleukocyte cell-cell adhesion
S0007186biological_processG protein-coupled receptor signaling pathway
S0007267biological_processcell-cell signaling
S0008009molecular_functionchemokine activity
S0009615biological_processresponse to virus
S0009636biological_processresponse to toxic substance
S0010536biological_processpositive regulation of activation of Janus kinase activity
S0010759biological_processpositive regulation of macrophage chemotaxis
S0010820biological_processpositive regulation of T cell chemotaxis
S0014911biological_processpositive regulation of smooth muscle cell migration
S0016004molecular_functionphospholipase activator activity
S0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
S0030335biological_processpositive regulation of cell migration
S0031328biological_processpositive regulation of cellular biosynthetic process
S0031584biological_processactivation of phospholipase D activity
S0031726molecular_functionCCR1 chemokine receptor binding
S0031729molecular_functionCCR4 chemokine receptor binding
S0031730molecular_functionCCR5 chemokine receptor binding
S0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
S0034097biological_processresponse to cytokine
S0034112biological_processpositive regulation of homotypic cell-cell adhesion
S0034612biological_processresponse to tumor necrosis factor
S0042056molecular_functionchemoattractant activity
S0042102biological_processpositive regulation of T cell proliferation
S0042119biological_processneutrophil activation
S0042327biological_processpositive regulation of phosphorylation
S0042379molecular_functionchemokine receptor binding
S0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
S0042802molecular_functionidentical protein binding
S0042803molecular_functionprotein homodimerization activity
S0043922biological_processnegative regulation by host of viral transcription
S0044344biological_processcellular response to fibroblast growth factor stimulus
S0045070biological_processpositive regulation of viral genome replication
S0045071biological_processnegative regulation of viral genome replication
S0045089biological_processpositive regulation of innate immune response
S0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
S0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
S0045785biological_processpositive regulation of cell adhesion
S0045948biological_processpositive regulation of translational initiation
S0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
S0046817molecular_functionchemokine receptor antagonist activity
S0048020molecular_functionCCR chemokine receptor binding
S0048245biological_processeosinophil chemotaxis
S0048246biological_processmacrophage chemotaxis
S0048661biological_processpositive regulation of smooth muscle cell proliferation
S0050673biological_processepithelial cell proliferation
S0050679biological_processpositive regulation of epithelial cell proliferation
S0050796biological_processregulation of insulin secretion
S0050863biological_processregulation of T cell activation
S0050918biological_processpositive chemotaxis
S0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
S0051928biological_processpositive regulation of calcium ion transport
S0060326biological_processcell chemotaxis
S0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
S0070098biological_processchemokine-mediated signaling pathway
S0070100biological_processnegative regulation of chemokine-mediated signaling pathway
S0070233biological_processnegative regulation of T cell apoptotic process
S0070234biological_processpositive regulation of T cell apoptotic process
S0071346biological_processcellular response to type II interferon
S0071347biological_processcellular response to interleukin-1
S0071356biological_processcellular response to tumor necrosis factor
S0090026biological_processpositive regulation of monocyte chemotaxis
S0098586biological_processcellular response to virus
S2000110biological_processnegative regulation of macrophage apoptotic process
S2000406biological_processpositive regulation of T cell migration
S2000503biological_processpositive regulation of natural killer cell chemotaxis
T0002407biological_processdendritic cell chemotaxis
T0002548biological_processmonocyte chemotaxis
T0002676biological_processregulation of chronic inflammatory response
T0004435molecular_functionphosphatidylinositol phospholipase C activity
T0004672molecular_functionprotein kinase activity
T0005125molecular_functioncytokine activity
T0005515molecular_functionprotein binding
T0005576cellular_componentextracellular region
T0005615cellular_componentextracellular space
T0005737cellular_componentcytoplasm
T0006816biological_processcalcium ion transport
T0006874biological_processintracellular calcium ion homeostasis
T0006887biological_processexocytosis
T0006935biological_processchemotaxis
T0006954biological_processinflammatory response
T0006955biological_processimmune response
T0007159biological_processleukocyte cell-cell adhesion
T0007186biological_processG protein-coupled receptor signaling pathway
T0007267biological_processcell-cell signaling
T0008009molecular_functionchemokine activity
T0009615biological_processresponse to virus
T0009636biological_processresponse to toxic substance
T0010536biological_processpositive regulation of activation of Janus kinase activity
T0010759biological_processpositive regulation of macrophage chemotaxis
T0010820biological_processpositive regulation of T cell chemotaxis
T0014911biological_processpositive regulation of smooth muscle cell migration
T0016004molecular_functionphospholipase activator activity
T0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
T0030335biological_processpositive regulation of cell migration
T0031328biological_processpositive regulation of cellular biosynthetic process
T0031584biological_processactivation of phospholipase D activity
T0031726molecular_functionCCR1 chemokine receptor binding
T0031729molecular_functionCCR4 chemokine receptor binding
T0031730molecular_functionCCR5 chemokine receptor binding
T0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
T0034097biological_processresponse to cytokine
T0034112biological_processpositive regulation of homotypic cell-cell adhesion
T0034612biological_processresponse to tumor necrosis factor
T0042056molecular_functionchemoattractant activity
T0042102biological_processpositive regulation of T cell proliferation
T0042119biological_processneutrophil activation
T0042327biological_processpositive regulation of phosphorylation
T0042379molecular_functionchemokine receptor binding
T0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
T0042802molecular_functionidentical protein binding
T0042803molecular_functionprotein homodimerization activity
T0043922biological_processnegative regulation by host of viral transcription
T0044344biological_processcellular response to fibroblast growth factor stimulus
T0045070biological_processpositive regulation of viral genome replication
T0045071biological_processnegative regulation of viral genome replication
T0045089biological_processpositive regulation of innate immune response
T0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
T0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
T0045785biological_processpositive regulation of cell adhesion
T0045948biological_processpositive regulation of translational initiation
T0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
T0046817molecular_functionchemokine receptor antagonist activity
T0048020molecular_functionCCR chemokine receptor binding
T0048245biological_processeosinophil chemotaxis
T0048246biological_processmacrophage chemotaxis
T0048661biological_processpositive regulation of smooth muscle cell proliferation
T0050673biological_processepithelial cell proliferation
T0050679biological_processpositive regulation of epithelial cell proliferation
T0050796biological_processregulation of insulin secretion
T0050863biological_processregulation of T cell activation
T0050918biological_processpositive chemotaxis
T0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
T0051928biological_processpositive regulation of calcium ion transport
T0060326biological_processcell chemotaxis
T0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
T0070098biological_processchemokine-mediated signaling pathway
T0070100biological_processnegative regulation of chemokine-mediated signaling pathway
T0070233biological_processnegative regulation of T cell apoptotic process
T0070234biological_processpositive regulation of T cell apoptotic process
T0071346biological_processcellular response to type II interferon
T0071347biological_processcellular response to interleukin-1
T0071356biological_processcellular response to tumor necrosis factor
T0090026biological_processpositive regulation of monocyte chemotaxis
T0098586biological_processcellular response to virus
T2000110biological_processnegative regulation of macrophage apoptotic process
T2000406biological_processpositive regulation of T cell migration
T2000503biological_processpositive regulation of natural killer cell chemotaxis
Functional Information from PROSITE/UniProt
site_idPS00472
Number of Residues42
DetailsSMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCFayiarp..LprahIkeYfytsgk..Csnp.AVVFvtrknrqv.CA
ChainResidueDetails
ACYS10-ALA51

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsMOD_RES: Methionine sulfoxide => ECO:0000269|PubMed:1380064
ChainResidueDetails
FMET67
AMET67
BMET67
CMET67
DMET67
EMET67
GMET67
HMET67
IMET67
JMET67
KMET67
LMET67
SMET67
TMET67
MMET67
NMET67
OMET67
PMET67
QMET67
RMET67

site_idSWS_FT_FI2
Number of Residues40
DetailsCARBOHYD: O-linked (GalNAc...) serine; partial => ECO:0000269|PubMed:1380064
ChainResidueDetails
ASER4
ASER5
BSER4
BSER5
CSER4
CSER5
DSER4
DSER5
ESER4
ESER5
FSER4
FSER5
GSER4
GSER5
HSER4
HSER5
ISER4
ISER5
JSER4
JSER5
KSER4
KSER5
LSER4
LSER5
SSER4
SSER5
TSER4
TSER5
MSER4
MSER5
NSER4
NSER5
OSER4
OSER5
PSER4
PSER5
QSER4
QSER5
RSER4
RSER5

220472

PDB entries from 2024-05-29

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