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6C6D

20mer crystal structure of CC chemokine 5 (CCL5)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002407biological_processdendritic cell chemotaxis
A0002548biological_processmonocyte chemotaxis
A0002676biological_processregulation of chronic inflammatory response
A0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
A0004672molecular_functionprotein kinase activity
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0006816biological_processcalcium ion transport
A0006874biological_processintracellular calcium ion homeostasis
A0006887biological_processexocytosis
A0006935biological_processchemotaxis
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007159biological_processleukocyte cell-cell adhesion
A0007186biological_processG protein-coupled receptor signaling pathway
A0007267biological_processcell-cell signaling
A0008009molecular_functionchemokine activity
A0009615biological_processresponse to virus
A0009636biological_processresponse to toxic substance
A0010759biological_processpositive regulation of macrophage chemotaxis
A0010820biological_processpositive regulation of T cell chemotaxis
A0014911biological_processpositive regulation of smooth muscle cell migration
A0016004molecular_functionphospholipase activator activity
A0016020cellular_componentmembrane
A0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
A0030335biological_processpositive regulation of cell migration
A0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
A0031726molecular_functionCCR1 chemokine receptor binding
A0031729molecular_functionCCR4 chemokine receptor binding
A0031730molecular_functionCCR5 chemokine receptor binding
A0032008biological_processpositive regulation of TOR signaling
A0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
A0034097biological_processresponse to cytokine
A0034112biological_processpositive regulation of homotypic cell-cell adhesion
A0034612biological_processresponse to tumor necrosis factor
A0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
A0042056molecular_functionchemoattractant activity
A0042102biological_processpositive regulation of T cell proliferation
A0042119biological_processneutrophil activation
A0042379molecular_functionchemokine receptor binding
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043922biological_processhost-mediated suppression of viral transcription
A0044344biological_processcellular response to fibroblast growth factor stimulus
A0045070biological_processpositive regulation of viral genome replication
A0045071biological_processnegative regulation of viral genome replication
A0045089biological_processpositive regulation of innate immune response
A0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
A0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
A0045785biological_processpositive regulation of cell adhesion
A0045948biological_processpositive regulation of translational initiation
A0046817molecular_functionchemokine receptor antagonist activity
A0048020molecular_functionCCR chemokine receptor binding
A0048245biological_processeosinophil chemotaxis
A0048246biological_processmacrophage chemotaxis
A0048661biological_processpositive regulation of smooth muscle cell proliferation
A0050673biological_processepithelial cell proliferation
A0050679biological_processpositive regulation of epithelial cell proliferation
A0050796biological_processregulation of insulin secretion
A0050863biological_processregulation of T cell activation
A0050918biological_processpositive chemotaxis
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0051928biological_processpositive regulation of calcium ion transport
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0070098biological_processchemokine-mediated signaling pathway
A0070100biological_processnegative regulation of chemokine-mediated signaling pathway
A0070233biological_processnegative regulation of T cell apoptotic process
A0070234biological_processpositive regulation of T cell apoptotic process
A0071346biological_processcellular response to type II interferon
A0071347biological_processcellular response to interleukin-1
A0071356biological_processcellular response to tumor necrosis factor
A0090026biological_processpositive regulation of monocyte chemotaxis
A0097696biological_processcell surface receptor signaling pathway via STAT
A0098586biological_processcellular response to virus
A0150078biological_processpositive regulation of neuroinflammatory response
A1904894biological_processpositive regulation of receptor signaling pathway via STAT
A2000110biological_processnegative regulation of macrophage apoptotic process
A2000406biological_processpositive regulation of T cell migration
A2000503biological_processpositive regulation of natural killer cell chemotaxis
B0002407biological_processdendritic cell chemotaxis
B0002548biological_processmonocyte chemotaxis
B0002676biological_processregulation of chronic inflammatory response
B0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
B0004672molecular_functionprotein kinase activity
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0006816biological_processcalcium ion transport
B0006874biological_processintracellular calcium ion homeostasis
B0006887biological_processexocytosis
B0006935biological_processchemotaxis
B0006954biological_processinflammatory response
B0006955biological_processimmune response
B0007159biological_processleukocyte cell-cell adhesion
B0007186biological_processG protein-coupled receptor signaling pathway
B0007267biological_processcell-cell signaling
B0008009molecular_functionchemokine activity
B0009615biological_processresponse to virus
B0009636biological_processresponse to toxic substance
B0010759biological_processpositive regulation of macrophage chemotaxis
B0010820biological_processpositive regulation of T cell chemotaxis
B0014911biological_processpositive regulation of smooth muscle cell migration
B0016004molecular_functionphospholipase activator activity
B0016020cellular_componentmembrane
B0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
B0030335biological_processpositive regulation of cell migration
B0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
B0031726molecular_functionCCR1 chemokine receptor binding
B0031729molecular_functionCCR4 chemokine receptor binding
B0031730molecular_functionCCR5 chemokine receptor binding
B0032008biological_processpositive regulation of TOR signaling
B0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
B0034097biological_processresponse to cytokine
B0034112biological_processpositive regulation of homotypic cell-cell adhesion
B0034612biological_processresponse to tumor necrosis factor
B0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
B0042056molecular_functionchemoattractant activity
B0042102biological_processpositive regulation of T cell proliferation
B0042119biological_processneutrophil activation
B0042379molecular_functionchemokine receptor binding
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043922biological_processhost-mediated suppression of viral transcription
B0044344biological_processcellular response to fibroblast growth factor stimulus
B0045070biological_processpositive regulation of viral genome replication
B0045071biological_processnegative regulation of viral genome replication
B0045089biological_processpositive regulation of innate immune response
B0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
B0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
B0045785biological_processpositive regulation of cell adhesion
B0045948biological_processpositive regulation of translational initiation
B0046817molecular_functionchemokine receptor antagonist activity
B0048020molecular_functionCCR chemokine receptor binding
B0048245biological_processeosinophil chemotaxis
B0048246biological_processmacrophage chemotaxis
B0048661biological_processpositive regulation of smooth muscle cell proliferation
B0050673biological_processepithelial cell proliferation
B0050679biological_processpositive regulation of epithelial cell proliferation
B0050796biological_processregulation of insulin secretion
B0050863biological_processregulation of T cell activation
B0050918biological_processpositive chemotaxis
B0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B0051928biological_processpositive regulation of calcium ion transport
B0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
B0070098biological_processchemokine-mediated signaling pathway
B0070100biological_processnegative regulation of chemokine-mediated signaling pathway
B0070233biological_processnegative regulation of T cell apoptotic process
B0070234biological_processpositive regulation of T cell apoptotic process
B0071346biological_processcellular response to type II interferon
B0071347biological_processcellular response to interleukin-1
B0071356biological_processcellular response to tumor necrosis factor
B0090026biological_processpositive regulation of monocyte chemotaxis
B0097696biological_processcell surface receptor signaling pathway via STAT
B0098586biological_processcellular response to virus
B0150078biological_processpositive regulation of neuroinflammatory response
B1904894biological_processpositive regulation of receptor signaling pathway via STAT
B2000110biological_processnegative regulation of macrophage apoptotic process
B2000406biological_processpositive regulation of T cell migration
B2000503biological_processpositive regulation of natural killer cell chemotaxis
C0002407biological_processdendritic cell chemotaxis
C0002548biological_processmonocyte chemotaxis
C0002676biological_processregulation of chronic inflammatory response
C0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
C0004672molecular_functionprotein kinase activity
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005737cellular_componentcytoplasm
C0006816biological_processcalcium ion transport
C0006874biological_processintracellular calcium ion homeostasis
C0006887biological_processexocytosis
C0006935biological_processchemotaxis
C0006954biological_processinflammatory response
C0006955biological_processimmune response
C0007159biological_processleukocyte cell-cell adhesion
C0007186biological_processG protein-coupled receptor signaling pathway
C0007267biological_processcell-cell signaling
C0008009molecular_functionchemokine activity
C0009615biological_processresponse to virus
C0009636biological_processresponse to toxic substance
C0010759biological_processpositive regulation of macrophage chemotaxis
C0010820biological_processpositive regulation of T cell chemotaxis
C0014911biological_processpositive regulation of smooth muscle cell migration
C0016004molecular_functionphospholipase activator activity
C0016020cellular_componentmembrane
C0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
C0030335biological_processpositive regulation of cell migration
C0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
C0031726molecular_functionCCR1 chemokine receptor binding
C0031729molecular_functionCCR4 chemokine receptor binding
C0031730molecular_functionCCR5 chemokine receptor binding
C0032008biological_processpositive regulation of TOR signaling
C0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
C0034097biological_processresponse to cytokine
C0034112biological_processpositive regulation of homotypic cell-cell adhesion
C0034612biological_processresponse to tumor necrosis factor
C0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
C0042056molecular_functionchemoattractant activity
C0042102biological_processpositive regulation of T cell proliferation
C0042119biological_processneutrophil activation
C0042379molecular_functionchemokine receptor binding
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043922biological_processhost-mediated suppression of viral transcription
C0044344biological_processcellular response to fibroblast growth factor stimulus
C0045070biological_processpositive regulation of viral genome replication
C0045071biological_processnegative regulation of viral genome replication
C0045089biological_processpositive regulation of innate immune response
C0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
C0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
C0045785biological_processpositive regulation of cell adhesion
C0045948biological_processpositive regulation of translational initiation
C0046817molecular_functionchemokine receptor antagonist activity
C0048020molecular_functionCCR chemokine receptor binding
C0048245biological_processeosinophil chemotaxis
C0048246biological_processmacrophage chemotaxis
C0048661biological_processpositive regulation of smooth muscle cell proliferation
C0050673biological_processepithelial cell proliferation
C0050679biological_processpositive regulation of epithelial cell proliferation
C0050796biological_processregulation of insulin secretion
C0050863biological_processregulation of T cell activation
C0050918biological_processpositive chemotaxis
C0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C0051928biological_processpositive regulation of calcium ion transport
C0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
C0070098biological_processchemokine-mediated signaling pathway
C0070100biological_processnegative regulation of chemokine-mediated signaling pathway
C0070233biological_processnegative regulation of T cell apoptotic process
C0070234biological_processpositive regulation of T cell apoptotic process
C0071346biological_processcellular response to type II interferon
C0071347biological_processcellular response to interleukin-1
C0071356biological_processcellular response to tumor necrosis factor
C0090026biological_processpositive regulation of monocyte chemotaxis
C0097696biological_processcell surface receptor signaling pathway via STAT
C0098586biological_processcellular response to virus
C0150078biological_processpositive regulation of neuroinflammatory response
C1904894biological_processpositive regulation of receptor signaling pathway via STAT
C2000110biological_processnegative regulation of macrophage apoptotic process
C2000406biological_processpositive regulation of T cell migration
C2000503biological_processpositive regulation of natural killer cell chemotaxis
D0002407biological_processdendritic cell chemotaxis
D0002548biological_processmonocyte chemotaxis
D0002676biological_processregulation of chronic inflammatory response
D0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
D0004672molecular_functionprotein kinase activity
D0005125molecular_functioncytokine activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005737cellular_componentcytoplasm
D0006816biological_processcalcium ion transport
D0006874biological_processintracellular calcium ion homeostasis
D0006887biological_processexocytosis
D0006935biological_processchemotaxis
D0006954biological_processinflammatory response
D0006955biological_processimmune response
D0007159biological_processleukocyte cell-cell adhesion
D0007186biological_processG protein-coupled receptor signaling pathway
D0007267biological_processcell-cell signaling
D0008009molecular_functionchemokine activity
D0009615biological_processresponse to virus
D0009636biological_processresponse to toxic substance
D0010759biological_processpositive regulation of macrophage chemotaxis
D0010820biological_processpositive regulation of T cell chemotaxis
D0014911biological_processpositive regulation of smooth muscle cell migration
D0016004molecular_functionphospholipase activator activity
D0016020cellular_componentmembrane
D0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
D0030335biological_processpositive regulation of cell migration
D0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
D0031726molecular_functionCCR1 chemokine receptor binding
D0031729molecular_functionCCR4 chemokine receptor binding
D0031730molecular_functionCCR5 chemokine receptor binding
D0032008biological_processpositive regulation of TOR signaling
D0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
D0034097biological_processresponse to cytokine
D0034112biological_processpositive regulation of homotypic cell-cell adhesion
D0034612biological_processresponse to tumor necrosis factor
D0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
D0042056molecular_functionchemoattractant activity
D0042102biological_processpositive regulation of T cell proliferation
D0042119biological_processneutrophil activation
D0042379molecular_functionchemokine receptor binding
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043922biological_processhost-mediated suppression of viral transcription
D0044344biological_processcellular response to fibroblast growth factor stimulus
D0045070biological_processpositive regulation of viral genome replication
D0045071biological_processnegative regulation of viral genome replication
D0045089biological_processpositive regulation of innate immune response
D0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
D0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
D0045785biological_processpositive regulation of cell adhesion
D0045948biological_processpositive regulation of translational initiation
D0046817molecular_functionchemokine receptor antagonist activity
D0048020molecular_functionCCR chemokine receptor binding
D0048245biological_processeosinophil chemotaxis
D0048246biological_processmacrophage chemotaxis
D0048661biological_processpositive regulation of smooth muscle cell proliferation
D0050673biological_processepithelial cell proliferation
D0050679biological_processpositive regulation of epithelial cell proliferation
D0050796biological_processregulation of insulin secretion
D0050863biological_processregulation of T cell activation
D0050918biological_processpositive chemotaxis
D0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
D0051928biological_processpositive regulation of calcium ion transport
D0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
D0070098biological_processchemokine-mediated signaling pathway
D0070100biological_processnegative regulation of chemokine-mediated signaling pathway
D0070233biological_processnegative regulation of T cell apoptotic process
D0070234biological_processpositive regulation of T cell apoptotic process
D0071346biological_processcellular response to type II interferon
D0071347biological_processcellular response to interleukin-1
D0071356biological_processcellular response to tumor necrosis factor
D0090026biological_processpositive regulation of monocyte chemotaxis
D0097696biological_processcell surface receptor signaling pathway via STAT
D0098586biological_processcellular response to virus
D0150078biological_processpositive regulation of neuroinflammatory response
D1904894biological_processpositive regulation of receptor signaling pathway via STAT
D2000110biological_processnegative regulation of macrophage apoptotic process
D2000406biological_processpositive regulation of T cell migration
D2000503biological_processpositive regulation of natural killer cell chemotaxis
E0002407biological_processdendritic cell chemotaxis
E0002548biological_processmonocyte chemotaxis
E0002676biological_processregulation of chronic inflammatory response
E0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
E0004672molecular_functionprotein kinase activity
E0005125molecular_functioncytokine activity
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005737cellular_componentcytoplasm
E0006816biological_processcalcium ion transport
E0006874biological_processintracellular calcium ion homeostasis
E0006887biological_processexocytosis
E0006935biological_processchemotaxis
E0006954biological_processinflammatory response
E0006955biological_processimmune response
E0007159biological_processleukocyte cell-cell adhesion
E0007186biological_processG protein-coupled receptor signaling pathway
E0007267biological_processcell-cell signaling
E0008009molecular_functionchemokine activity
E0009615biological_processresponse to virus
E0009636biological_processresponse to toxic substance
E0010759biological_processpositive regulation of macrophage chemotaxis
E0010820biological_processpositive regulation of T cell chemotaxis
E0014911biological_processpositive regulation of smooth muscle cell migration
E0016004molecular_functionphospholipase activator activity
E0016020cellular_componentmembrane
E0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
E0030335biological_processpositive regulation of cell migration
E0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
E0031726molecular_functionCCR1 chemokine receptor binding
E0031729molecular_functionCCR4 chemokine receptor binding
E0031730molecular_functionCCR5 chemokine receptor binding
E0032008biological_processpositive regulation of TOR signaling
E0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
E0034097biological_processresponse to cytokine
E0034112biological_processpositive regulation of homotypic cell-cell adhesion
E0034612biological_processresponse to tumor necrosis factor
E0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
E0042056molecular_functionchemoattractant activity
E0042102biological_processpositive regulation of T cell proliferation
E0042119biological_processneutrophil activation
E0042379molecular_functionchemokine receptor binding
E0042802molecular_functionidentical protein binding
E0042803molecular_functionprotein homodimerization activity
E0043922biological_processhost-mediated suppression of viral transcription
E0044344biological_processcellular response to fibroblast growth factor stimulus
E0045070biological_processpositive regulation of viral genome replication
E0045071biological_processnegative regulation of viral genome replication
E0045089biological_processpositive regulation of innate immune response
E0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
E0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
E0045785biological_processpositive regulation of cell adhesion
E0045948biological_processpositive regulation of translational initiation
E0046817molecular_functionchemokine receptor antagonist activity
E0048020molecular_functionCCR chemokine receptor binding
E0048245biological_processeosinophil chemotaxis
E0048246biological_processmacrophage chemotaxis
E0048661biological_processpositive regulation of smooth muscle cell proliferation
E0050673biological_processepithelial cell proliferation
E0050679biological_processpositive regulation of epithelial cell proliferation
E0050796biological_processregulation of insulin secretion
E0050863biological_processregulation of T cell activation
E0050918biological_processpositive chemotaxis
E0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
E0051928biological_processpositive regulation of calcium ion transport
E0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
E0070098biological_processchemokine-mediated signaling pathway
E0070100biological_processnegative regulation of chemokine-mediated signaling pathway
E0070233biological_processnegative regulation of T cell apoptotic process
E0070234biological_processpositive regulation of T cell apoptotic process
E0071346biological_processcellular response to type II interferon
E0071347biological_processcellular response to interleukin-1
E0071356biological_processcellular response to tumor necrosis factor
E0090026biological_processpositive regulation of monocyte chemotaxis
E0097696biological_processcell surface receptor signaling pathway via STAT
E0098586biological_processcellular response to virus
E0150078biological_processpositive regulation of neuroinflammatory response
E1904894biological_processpositive regulation of receptor signaling pathway via STAT
E2000110biological_processnegative regulation of macrophage apoptotic process
E2000406biological_processpositive regulation of T cell migration
E2000503biological_processpositive regulation of natural killer cell chemotaxis
F0002407biological_processdendritic cell chemotaxis
F0002548biological_processmonocyte chemotaxis
F0002676biological_processregulation of chronic inflammatory response
F0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
F0004672molecular_functionprotein kinase activity
F0005125molecular_functioncytokine activity
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005737cellular_componentcytoplasm
F0006816biological_processcalcium ion transport
F0006874biological_processintracellular calcium ion homeostasis
F0006887biological_processexocytosis
F0006935biological_processchemotaxis
F0006954biological_processinflammatory response
F0006955biological_processimmune response
F0007159biological_processleukocyte cell-cell adhesion
F0007186biological_processG protein-coupled receptor signaling pathway
F0007267biological_processcell-cell signaling
F0008009molecular_functionchemokine activity
F0009615biological_processresponse to virus
F0009636biological_processresponse to toxic substance
F0010759biological_processpositive regulation of macrophage chemotaxis
F0010820biological_processpositive regulation of T cell chemotaxis
F0014911biological_processpositive regulation of smooth muscle cell migration
F0016004molecular_functionphospholipase activator activity
F0016020cellular_componentmembrane
F0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
F0030335biological_processpositive regulation of cell migration
F0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
F0031726molecular_functionCCR1 chemokine receptor binding
F0031729molecular_functionCCR4 chemokine receptor binding
F0031730molecular_functionCCR5 chemokine receptor binding
F0032008biological_processpositive regulation of TOR signaling
F0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
F0034097biological_processresponse to cytokine
F0034112biological_processpositive regulation of homotypic cell-cell adhesion
F0034612biological_processresponse to tumor necrosis factor
F0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
F0042056molecular_functionchemoattractant activity
F0042102biological_processpositive regulation of T cell proliferation
F0042119biological_processneutrophil activation
F0042379molecular_functionchemokine receptor binding
F0042802molecular_functionidentical protein binding
F0042803molecular_functionprotein homodimerization activity
F0043922biological_processhost-mediated suppression of viral transcription
F0044344biological_processcellular response to fibroblast growth factor stimulus
F0045070biological_processpositive regulation of viral genome replication
F0045071biological_processnegative regulation of viral genome replication
F0045089biological_processpositive regulation of innate immune response
F0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
F0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
F0045785biological_processpositive regulation of cell adhesion
F0045948biological_processpositive regulation of translational initiation
F0046817molecular_functionchemokine receptor antagonist activity
F0048020molecular_functionCCR chemokine receptor binding
F0048245biological_processeosinophil chemotaxis
F0048246biological_processmacrophage chemotaxis
F0048661biological_processpositive regulation of smooth muscle cell proliferation
F0050673biological_processepithelial cell proliferation
F0050679biological_processpositive regulation of epithelial cell proliferation
F0050796biological_processregulation of insulin secretion
F0050863biological_processregulation of T cell activation
F0050918biological_processpositive chemotaxis
F0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
F0051928biological_processpositive regulation of calcium ion transport
F0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
F0070098biological_processchemokine-mediated signaling pathway
F0070100biological_processnegative regulation of chemokine-mediated signaling pathway
F0070233biological_processnegative regulation of T cell apoptotic process
F0070234biological_processpositive regulation of T cell apoptotic process
F0071346biological_processcellular response to type II interferon
F0071347biological_processcellular response to interleukin-1
F0071356biological_processcellular response to tumor necrosis factor
F0090026biological_processpositive regulation of monocyte chemotaxis
F0097696biological_processcell surface receptor signaling pathway via STAT
F0098586biological_processcellular response to virus
F0150078biological_processpositive regulation of neuroinflammatory response
F1904894biological_processpositive regulation of receptor signaling pathway via STAT
F2000110biological_processnegative regulation of macrophage apoptotic process
F2000406biological_processpositive regulation of T cell migration
F2000503biological_processpositive regulation of natural killer cell chemotaxis
G0002407biological_processdendritic cell chemotaxis
G0002548biological_processmonocyte chemotaxis
G0002676biological_processregulation of chronic inflammatory response
G0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
G0004672molecular_functionprotein kinase activity
G0005125molecular_functioncytokine activity
G0005515molecular_functionprotein binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005737cellular_componentcytoplasm
G0006816biological_processcalcium ion transport
G0006874biological_processintracellular calcium ion homeostasis
G0006887biological_processexocytosis
G0006935biological_processchemotaxis
G0006954biological_processinflammatory response
G0006955biological_processimmune response
G0007159biological_processleukocyte cell-cell adhesion
G0007186biological_processG protein-coupled receptor signaling pathway
G0007267biological_processcell-cell signaling
G0008009molecular_functionchemokine activity
G0009615biological_processresponse to virus
G0009636biological_processresponse to toxic substance
G0010759biological_processpositive regulation of macrophage chemotaxis
G0010820biological_processpositive regulation of T cell chemotaxis
G0014911biological_processpositive regulation of smooth muscle cell migration
G0016004molecular_functionphospholipase activator activity
G0016020cellular_componentmembrane
G0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
G0030335biological_processpositive regulation of cell migration
G0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
G0031726molecular_functionCCR1 chemokine receptor binding
G0031729molecular_functionCCR4 chemokine receptor binding
G0031730molecular_functionCCR5 chemokine receptor binding
G0032008biological_processpositive regulation of TOR signaling
G0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
G0034097biological_processresponse to cytokine
G0034112biological_processpositive regulation of homotypic cell-cell adhesion
G0034612biological_processresponse to tumor necrosis factor
G0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
G0042056molecular_functionchemoattractant activity
G0042102biological_processpositive regulation of T cell proliferation
G0042119biological_processneutrophil activation
G0042379molecular_functionchemokine receptor binding
G0042802molecular_functionidentical protein binding
G0042803molecular_functionprotein homodimerization activity
G0043922biological_processhost-mediated suppression of viral transcription
G0044344biological_processcellular response to fibroblast growth factor stimulus
G0045070biological_processpositive regulation of viral genome replication
G0045071biological_processnegative regulation of viral genome replication
G0045089biological_processpositive regulation of innate immune response
G0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
G0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
G0045785biological_processpositive regulation of cell adhesion
G0045948biological_processpositive regulation of translational initiation
G0046817molecular_functionchemokine receptor antagonist activity
G0048020molecular_functionCCR chemokine receptor binding
G0048245biological_processeosinophil chemotaxis
G0048246biological_processmacrophage chemotaxis
G0048661biological_processpositive regulation of smooth muscle cell proliferation
G0050673biological_processepithelial cell proliferation
G0050679biological_processpositive regulation of epithelial cell proliferation
G0050796biological_processregulation of insulin secretion
G0050863biological_processregulation of T cell activation
G0050918biological_processpositive chemotaxis
G0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
G0051928biological_processpositive regulation of calcium ion transport
G0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
G0070098biological_processchemokine-mediated signaling pathway
G0070100biological_processnegative regulation of chemokine-mediated signaling pathway
G0070233biological_processnegative regulation of T cell apoptotic process
G0070234biological_processpositive regulation of T cell apoptotic process
G0071346biological_processcellular response to type II interferon
G0071347biological_processcellular response to interleukin-1
G0071356biological_processcellular response to tumor necrosis factor
G0090026biological_processpositive regulation of monocyte chemotaxis
G0097696biological_processcell surface receptor signaling pathway via STAT
G0098586biological_processcellular response to virus
G0150078biological_processpositive regulation of neuroinflammatory response
G1904894biological_processpositive regulation of receptor signaling pathway via STAT
G2000110biological_processnegative regulation of macrophage apoptotic process
G2000406biological_processpositive regulation of T cell migration
G2000503biological_processpositive regulation of natural killer cell chemotaxis
H0002407biological_processdendritic cell chemotaxis
H0002548biological_processmonocyte chemotaxis
H0002676biological_processregulation of chronic inflammatory response
H0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
H0004672molecular_functionprotein kinase activity
H0005125molecular_functioncytokine activity
H0005515molecular_functionprotein binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005737cellular_componentcytoplasm
H0006816biological_processcalcium ion transport
H0006874biological_processintracellular calcium ion homeostasis
H0006887biological_processexocytosis
H0006935biological_processchemotaxis
H0006954biological_processinflammatory response
H0006955biological_processimmune response
H0007159biological_processleukocyte cell-cell adhesion
H0007186biological_processG protein-coupled receptor signaling pathway
H0007267biological_processcell-cell signaling
H0008009molecular_functionchemokine activity
H0009615biological_processresponse to virus
H0009636biological_processresponse to toxic substance
H0010759biological_processpositive regulation of macrophage chemotaxis
H0010820biological_processpositive regulation of T cell chemotaxis
H0014911biological_processpositive regulation of smooth muscle cell migration
H0016004molecular_functionphospholipase activator activity
H0016020cellular_componentmembrane
H0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
H0030335biological_processpositive regulation of cell migration
H0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
H0031726molecular_functionCCR1 chemokine receptor binding
H0031729molecular_functionCCR4 chemokine receptor binding
H0031730molecular_functionCCR5 chemokine receptor binding
H0032008biological_processpositive regulation of TOR signaling
H0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
H0034097biological_processresponse to cytokine
H0034112biological_processpositive regulation of homotypic cell-cell adhesion
H0034612biological_processresponse to tumor necrosis factor
H0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
H0042056molecular_functionchemoattractant activity
H0042102biological_processpositive regulation of T cell proliferation
H0042119biological_processneutrophil activation
H0042379molecular_functionchemokine receptor binding
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0043922biological_processhost-mediated suppression of viral transcription
H0044344biological_processcellular response to fibroblast growth factor stimulus
H0045070biological_processpositive regulation of viral genome replication
H0045071biological_processnegative regulation of viral genome replication
H0045089biological_processpositive regulation of innate immune response
H0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
H0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
H0045785biological_processpositive regulation of cell adhesion
H0045948biological_processpositive regulation of translational initiation
H0046817molecular_functionchemokine receptor antagonist activity
H0048020molecular_functionCCR chemokine receptor binding
H0048245biological_processeosinophil chemotaxis
H0048246biological_processmacrophage chemotaxis
H0048661biological_processpositive regulation of smooth muscle cell proliferation
H0050673biological_processepithelial cell proliferation
H0050679biological_processpositive regulation of epithelial cell proliferation
H0050796biological_processregulation of insulin secretion
H0050863biological_processregulation of T cell activation
H0050918biological_processpositive chemotaxis
H0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
H0051928biological_processpositive regulation of calcium ion transport
H0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
H0070098biological_processchemokine-mediated signaling pathway
H0070100biological_processnegative regulation of chemokine-mediated signaling pathway
H0070233biological_processnegative regulation of T cell apoptotic process
H0070234biological_processpositive regulation of T cell apoptotic process
H0071346biological_processcellular response to type II interferon
H0071347biological_processcellular response to interleukin-1
H0071356biological_processcellular response to tumor necrosis factor
H0090026biological_processpositive regulation of monocyte chemotaxis
H0097696biological_processcell surface receptor signaling pathway via STAT
H0098586biological_processcellular response to virus
H0150078biological_processpositive regulation of neuroinflammatory response
H1904894biological_processpositive regulation of receptor signaling pathway via STAT
H2000110biological_processnegative regulation of macrophage apoptotic process
H2000406biological_processpositive regulation of T cell migration
H2000503biological_processpositive regulation of natural killer cell chemotaxis
I0002407biological_processdendritic cell chemotaxis
I0002548biological_processmonocyte chemotaxis
I0002676biological_processregulation of chronic inflammatory response
I0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
I0004672molecular_functionprotein kinase activity
I0005125molecular_functioncytokine activity
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005737cellular_componentcytoplasm
I0006816biological_processcalcium ion transport
I0006874biological_processintracellular calcium ion homeostasis
I0006887biological_processexocytosis
I0006935biological_processchemotaxis
I0006954biological_processinflammatory response
I0006955biological_processimmune response
I0007159biological_processleukocyte cell-cell adhesion
I0007186biological_processG protein-coupled receptor signaling pathway
I0007267biological_processcell-cell signaling
I0008009molecular_functionchemokine activity
I0009615biological_processresponse to virus
I0009636biological_processresponse to toxic substance
I0010759biological_processpositive regulation of macrophage chemotaxis
I0010820biological_processpositive regulation of T cell chemotaxis
I0014911biological_processpositive regulation of smooth muscle cell migration
I0016004molecular_functionphospholipase activator activity
I0016020cellular_componentmembrane
I0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
I0030335biological_processpositive regulation of cell migration
I0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
I0031726molecular_functionCCR1 chemokine receptor binding
I0031729molecular_functionCCR4 chemokine receptor binding
I0031730molecular_functionCCR5 chemokine receptor binding
I0032008biological_processpositive regulation of TOR signaling
I0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
I0034097biological_processresponse to cytokine
I0034112biological_processpositive regulation of homotypic cell-cell adhesion
I0034612biological_processresponse to tumor necrosis factor
I0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
I0042056molecular_functionchemoattractant activity
I0042102biological_processpositive regulation of T cell proliferation
I0042119biological_processneutrophil activation
I0042379molecular_functionchemokine receptor binding
I0042802molecular_functionidentical protein binding
I0042803molecular_functionprotein homodimerization activity
I0043922biological_processhost-mediated suppression of viral transcription
I0044344biological_processcellular response to fibroblast growth factor stimulus
I0045070biological_processpositive regulation of viral genome replication
I0045071biological_processnegative regulation of viral genome replication
I0045089biological_processpositive regulation of innate immune response
I0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
I0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
I0045785biological_processpositive regulation of cell adhesion
I0045948biological_processpositive regulation of translational initiation
I0046817molecular_functionchemokine receptor antagonist activity
I0048020molecular_functionCCR chemokine receptor binding
I0048245biological_processeosinophil chemotaxis
I0048246biological_processmacrophage chemotaxis
I0048661biological_processpositive regulation of smooth muscle cell proliferation
I0050673biological_processepithelial cell proliferation
I0050679biological_processpositive regulation of epithelial cell proliferation
I0050796biological_processregulation of insulin secretion
I0050863biological_processregulation of T cell activation
I0050918biological_processpositive chemotaxis
I0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
I0051928biological_processpositive regulation of calcium ion transport
I0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
I0070098biological_processchemokine-mediated signaling pathway
I0070100biological_processnegative regulation of chemokine-mediated signaling pathway
I0070233biological_processnegative regulation of T cell apoptotic process
I0070234biological_processpositive regulation of T cell apoptotic process
I0071346biological_processcellular response to type II interferon
I0071347biological_processcellular response to interleukin-1
I0071356biological_processcellular response to tumor necrosis factor
I0090026biological_processpositive regulation of monocyte chemotaxis
I0097696biological_processcell surface receptor signaling pathway via STAT
I0098586biological_processcellular response to virus
I0150078biological_processpositive regulation of neuroinflammatory response
I1904894biological_processpositive regulation of receptor signaling pathway via STAT
I2000110biological_processnegative regulation of macrophage apoptotic process
I2000406biological_processpositive regulation of T cell migration
I2000503biological_processpositive regulation of natural killer cell chemotaxis
J0002407biological_processdendritic cell chemotaxis
J0002548biological_processmonocyte chemotaxis
J0002676biological_processregulation of chronic inflammatory response
J0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
J0004672molecular_functionprotein kinase activity
J0005125molecular_functioncytokine activity
J0005515molecular_functionprotein binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005737cellular_componentcytoplasm
J0006816biological_processcalcium ion transport
J0006874biological_processintracellular calcium ion homeostasis
J0006887biological_processexocytosis
J0006935biological_processchemotaxis
J0006954biological_processinflammatory response
J0006955biological_processimmune response
J0007159biological_processleukocyte cell-cell adhesion
J0007186biological_processG protein-coupled receptor signaling pathway
J0007267biological_processcell-cell signaling
J0008009molecular_functionchemokine activity
J0009615biological_processresponse to virus
J0009636biological_processresponse to toxic substance
J0010759biological_processpositive regulation of macrophage chemotaxis
J0010820biological_processpositive regulation of T cell chemotaxis
J0014911biological_processpositive regulation of smooth muscle cell migration
J0016004molecular_functionphospholipase activator activity
J0016020cellular_componentmembrane
J0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
J0030335biological_processpositive regulation of cell migration
J0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
J0031726molecular_functionCCR1 chemokine receptor binding
J0031729molecular_functionCCR4 chemokine receptor binding
J0031730molecular_functionCCR5 chemokine receptor binding
J0032008biological_processpositive regulation of TOR signaling
J0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
J0034097biological_processresponse to cytokine
J0034112biological_processpositive regulation of homotypic cell-cell adhesion
J0034612biological_processresponse to tumor necrosis factor
J0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
J0042056molecular_functionchemoattractant activity
J0042102biological_processpositive regulation of T cell proliferation
J0042119biological_processneutrophil activation
J0042379molecular_functionchemokine receptor binding
J0042802molecular_functionidentical protein binding
J0042803molecular_functionprotein homodimerization activity
J0043922biological_processhost-mediated suppression of viral transcription
J0044344biological_processcellular response to fibroblast growth factor stimulus
J0045070biological_processpositive regulation of viral genome replication
J0045071biological_processnegative regulation of viral genome replication
J0045089biological_processpositive regulation of innate immune response
J0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
J0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
J0045785biological_processpositive regulation of cell adhesion
J0045948biological_processpositive regulation of translational initiation
J0046817molecular_functionchemokine receptor antagonist activity
J0048020molecular_functionCCR chemokine receptor binding
J0048245biological_processeosinophil chemotaxis
J0048246biological_processmacrophage chemotaxis
J0048661biological_processpositive regulation of smooth muscle cell proliferation
J0050673biological_processepithelial cell proliferation
J0050679biological_processpositive regulation of epithelial cell proliferation
J0050796biological_processregulation of insulin secretion
J0050863biological_processregulation of T cell activation
J0050918biological_processpositive chemotaxis
J0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
J0051928biological_processpositive regulation of calcium ion transport
J0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
J0070098biological_processchemokine-mediated signaling pathway
J0070100biological_processnegative regulation of chemokine-mediated signaling pathway
J0070233biological_processnegative regulation of T cell apoptotic process
J0070234biological_processpositive regulation of T cell apoptotic process
J0071346biological_processcellular response to type II interferon
J0071347biological_processcellular response to interleukin-1
J0071356biological_processcellular response to tumor necrosis factor
J0090026biological_processpositive regulation of monocyte chemotaxis
J0097696biological_processcell surface receptor signaling pathway via STAT
J0098586biological_processcellular response to virus
J0150078biological_processpositive regulation of neuroinflammatory response
J1904894biological_processpositive regulation of receptor signaling pathway via STAT
J2000110biological_processnegative regulation of macrophage apoptotic process
J2000406biological_processpositive regulation of T cell migration
J2000503biological_processpositive regulation of natural killer cell chemotaxis
K0002407biological_processdendritic cell chemotaxis
K0002548biological_processmonocyte chemotaxis
K0002676biological_processregulation of chronic inflammatory response
K0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
K0004672molecular_functionprotein kinase activity
K0005125molecular_functioncytokine activity
K0005515molecular_functionprotein binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005737cellular_componentcytoplasm
K0006816biological_processcalcium ion transport
K0006874biological_processintracellular calcium ion homeostasis
K0006887biological_processexocytosis
K0006935biological_processchemotaxis
K0006954biological_processinflammatory response
K0006955biological_processimmune response
K0007159biological_processleukocyte cell-cell adhesion
K0007186biological_processG protein-coupled receptor signaling pathway
K0007267biological_processcell-cell signaling
K0008009molecular_functionchemokine activity
K0009615biological_processresponse to virus
K0009636biological_processresponse to toxic substance
K0010759biological_processpositive regulation of macrophage chemotaxis
K0010820biological_processpositive regulation of T cell chemotaxis
K0014911biological_processpositive regulation of smooth muscle cell migration
K0016004molecular_functionphospholipase activator activity
K0016020cellular_componentmembrane
K0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
K0030335biological_processpositive regulation of cell migration
K0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
K0031726molecular_functionCCR1 chemokine receptor binding
K0031729molecular_functionCCR4 chemokine receptor binding
K0031730molecular_functionCCR5 chemokine receptor binding
K0032008biological_processpositive regulation of TOR signaling
K0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
K0034097biological_processresponse to cytokine
K0034112biological_processpositive regulation of homotypic cell-cell adhesion
K0034612biological_processresponse to tumor necrosis factor
K0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
K0042056molecular_functionchemoattractant activity
K0042102biological_processpositive regulation of T cell proliferation
K0042119biological_processneutrophil activation
K0042379molecular_functionchemokine receptor binding
K0042802molecular_functionidentical protein binding
K0042803molecular_functionprotein homodimerization activity
K0043922biological_processhost-mediated suppression of viral transcription
K0044344biological_processcellular response to fibroblast growth factor stimulus
K0045070biological_processpositive regulation of viral genome replication
K0045071biological_processnegative regulation of viral genome replication
K0045089biological_processpositive regulation of innate immune response
K0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
K0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
K0045785biological_processpositive regulation of cell adhesion
K0045948biological_processpositive regulation of translational initiation
K0046817molecular_functionchemokine receptor antagonist activity
K0048020molecular_functionCCR chemokine receptor binding
K0048245biological_processeosinophil chemotaxis
K0048246biological_processmacrophage chemotaxis
K0048661biological_processpositive regulation of smooth muscle cell proliferation
K0050673biological_processepithelial cell proliferation
K0050679biological_processpositive regulation of epithelial cell proliferation
K0050796biological_processregulation of insulin secretion
K0050863biological_processregulation of T cell activation
K0050918biological_processpositive chemotaxis
K0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
K0051928biological_processpositive regulation of calcium ion transport
K0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
K0070098biological_processchemokine-mediated signaling pathway
K0070100biological_processnegative regulation of chemokine-mediated signaling pathway
K0070233biological_processnegative regulation of T cell apoptotic process
K0070234biological_processpositive regulation of T cell apoptotic process
K0071346biological_processcellular response to type II interferon
K0071347biological_processcellular response to interleukin-1
K0071356biological_processcellular response to tumor necrosis factor
K0090026biological_processpositive regulation of monocyte chemotaxis
K0097696biological_processcell surface receptor signaling pathway via STAT
K0098586biological_processcellular response to virus
K0150078biological_processpositive regulation of neuroinflammatory response
K1904894biological_processpositive regulation of receptor signaling pathway via STAT
K2000110biological_processnegative regulation of macrophage apoptotic process
K2000406biological_processpositive regulation of T cell migration
K2000503biological_processpositive regulation of natural killer cell chemotaxis
L0002407biological_processdendritic cell chemotaxis
L0002548biological_processmonocyte chemotaxis
L0002676biological_processregulation of chronic inflammatory response
L0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
L0004672molecular_functionprotein kinase activity
L0005125molecular_functioncytokine activity
L0005515molecular_functionprotein binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005737cellular_componentcytoplasm
L0006816biological_processcalcium ion transport
L0006874biological_processintracellular calcium ion homeostasis
L0006887biological_processexocytosis
L0006935biological_processchemotaxis
L0006954biological_processinflammatory response
L0006955biological_processimmune response
L0007159biological_processleukocyte cell-cell adhesion
L0007186biological_processG protein-coupled receptor signaling pathway
L0007267biological_processcell-cell signaling
L0008009molecular_functionchemokine activity
L0009615biological_processresponse to virus
L0009636biological_processresponse to toxic substance
L0010759biological_processpositive regulation of macrophage chemotaxis
L0010820biological_processpositive regulation of T cell chemotaxis
L0014911biological_processpositive regulation of smooth muscle cell migration
L0016004molecular_functionphospholipase activator activity
L0016020cellular_componentmembrane
L0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
L0030335biological_processpositive regulation of cell migration
L0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
L0031726molecular_functionCCR1 chemokine receptor binding
L0031729molecular_functionCCR4 chemokine receptor binding
L0031730molecular_functionCCR5 chemokine receptor binding
L0032008biological_processpositive regulation of TOR signaling
L0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
L0034097biological_processresponse to cytokine
L0034112biological_processpositive regulation of homotypic cell-cell adhesion
L0034612biological_processresponse to tumor necrosis factor
L0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
L0042056molecular_functionchemoattractant activity
L0042102biological_processpositive regulation of T cell proliferation
L0042119biological_processneutrophil activation
L0042379molecular_functionchemokine receptor binding
L0042802molecular_functionidentical protein binding
L0042803molecular_functionprotein homodimerization activity
L0043922biological_processhost-mediated suppression of viral transcription
L0044344biological_processcellular response to fibroblast growth factor stimulus
L0045070biological_processpositive regulation of viral genome replication
L0045071biological_processnegative regulation of viral genome replication
L0045089biological_processpositive regulation of innate immune response
L0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
L0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
L0045785biological_processpositive regulation of cell adhesion
L0045948biological_processpositive regulation of translational initiation
L0046817molecular_functionchemokine receptor antagonist activity
L0048020molecular_functionCCR chemokine receptor binding
L0048245biological_processeosinophil chemotaxis
L0048246biological_processmacrophage chemotaxis
L0048661biological_processpositive regulation of smooth muscle cell proliferation
L0050673biological_processepithelial cell proliferation
L0050679biological_processpositive regulation of epithelial cell proliferation
L0050796biological_processregulation of insulin secretion
L0050863biological_processregulation of T cell activation
L0050918biological_processpositive chemotaxis
L0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
L0051928biological_processpositive regulation of calcium ion transport
L0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
L0070098biological_processchemokine-mediated signaling pathway
L0070100biological_processnegative regulation of chemokine-mediated signaling pathway
L0070233biological_processnegative regulation of T cell apoptotic process
L0070234biological_processpositive regulation of T cell apoptotic process
L0071346biological_processcellular response to type II interferon
L0071347biological_processcellular response to interleukin-1
L0071356biological_processcellular response to tumor necrosis factor
L0090026biological_processpositive regulation of monocyte chemotaxis
L0097696biological_processcell surface receptor signaling pathway via STAT
L0098586biological_processcellular response to virus
L0150078biological_processpositive regulation of neuroinflammatory response
L1904894biological_processpositive regulation of receptor signaling pathway via STAT
L2000110biological_processnegative regulation of macrophage apoptotic process
L2000406biological_processpositive regulation of T cell migration
L2000503biological_processpositive regulation of natural killer cell chemotaxis
M0002407biological_processdendritic cell chemotaxis
M0002548biological_processmonocyte chemotaxis
M0002676biological_processregulation of chronic inflammatory response
M0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
M0004672molecular_functionprotein kinase activity
M0005125molecular_functioncytokine activity
M0005515molecular_functionprotein binding
M0005576cellular_componentextracellular region
M0005615cellular_componentextracellular space
M0005737cellular_componentcytoplasm
M0006816biological_processcalcium ion transport
M0006874biological_processintracellular calcium ion homeostasis
M0006887biological_processexocytosis
M0006935biological_processchemotaxis
M0006954biological_processinflammatory response
M0006955biological_processimmune response
M0007159biological_processleukocyte cell-cell adhesion
M0007186biological_processG protein-coupled receptor signaling pathway
M0007267biological_processcell-cell signaling
M0008009molecular_functionchemokine activity
M0009615biological_processresponse to virus
M0009636biological_processresponse to toxic substance
M0010759biological_processpositive regulation of macrophage chemotaxis
M0010820biological_processpositive regulation of T cell chemotaxis
M0014911biological_processpositive regulation of smooth muscle cell migration
M0016004molecular_functionphospholipase activator activity
M0016020cellular_componentmembrane
M0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
M0030335biological_processpositive regulation of cell migration
M0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
M0031726molecular_functionCCR1 chemokine receptor binding
M0031729molecular_functionCCR4 chemokine receptor binding
M0031730molecular_functionCCR5 chemokine receptor binding
M0032008biological_processpositive regulation of TOR signaling
M0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
M0034097biological_processresponse to cytokine
M0034112biological_processpositive regulation of homotypic cell-cell adhesion
M0034612biological_processresponse to tumor necrosis factor
M0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
M0042056molecular_functionchemoattractant activity
M0042102biological_processpositive regulation of T cell proliferation
M0042119biological_processneutrophil activation
M0042379molecular_functionchemokine receptor binding
M0042802molecular_functionidentical protein binding
M0042803molecular_functionprotein homodimerization activity
M0043922biological_processhost-mediated suppression of viral transcription
M0044344biological_processcellular response to fibroblast growth factor stimulus
M0045070biological_processpositive regulation of viral genome replication
M0045071biological_processnegative regulation of viral genome replication
M0045089biological_processpositive regulation of innate immune response
M0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
M0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
M0045785biological_processpositive regulation of cell adhesion
M0045948biological_processpositive regulation of translational initiation
M0046817molecular_functionchemokine receptor antagonist activity
M0048020molecular_functionCCR chemokine receptor binding
M0048245biological_processeosinophil chemotaxis
M0048246biological_processmacrophage chemotaxis
M0048661biological_processpositive regulation of smooth muscle cell proliferation
M0050673biological_processepithelial cell proliferation
M0050679biological_processpositive regulation of epithelial cell proliferation
M0050796biological_processregulation of insulin secretion
M0050863biological_processregulation of T cell activation
M0050918biological_processpositive chemotaxis
M0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
M0051928biological_processpositive regulation of calcium ion transport
M0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
M0070098biological_processchemokine-mediated signaling pathway
M0070100biological_processnegative regulation of chemokine-mediated signaling pathway
M0070233biological_processnegative regulation of T cell apoptotic process
M0070234biological_processpositive regulation of T cell apoptotic process
M0071346biological_processcellular response to type II interferon
M0071347biological_processcellular response to interleukin-1
M0071356biological_processcellular response to tumor necrosis factor
M0090026biological_processpositive regulation of monocyte chemotaxis
M0097696biological_processcell surface receptor signaling pathway via STAT
M0098586biological_processcellular response to virus
M0150078biological_processpositive regulation of neuroinflammatory response
M1904894biological_processpositive regulation of receptor signaling pathway via STAT
M2000110biological_processnegative regulation of macrophage apoptotic process
M2000406biological_processpositive regulation of T cell migration
M2000503biological_processpositive regulation of natural killer cell chemotaxis
N0002407biological_processdendritic cell chemotaxis
N0002548biological_processmonocyte chemotaxis
N0002676biological_processregulation of chronic inflammatory response
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N0005615cellular_componentextracellular space
N0005737cellular_componentcytoplasm
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N0006874biological_processintracellular calcium ion homeostasis
N0006887biological_processexocytosis
N0006935biological_processchemotaxis
N0006954biological_processinflammatory response
N0006955biological_processimmune response
N0007159biological_processleukocyte cell-cell adhesion
N0007186biological_processG protein-coupled receptor signaling pathway
N0007267biological_processcell-cell signaling
N0008009molecular_functionchemokine activity
N0009615biological_processresponse to virus
N0009636biological_processresponse to toxic substance
N0010759biological_processpositive regulation of macrophage chemotaxis
N0010820biological_processpositive regulation of T cell chemotaxis
N0014911biological_processpositive regulation of smooth muscle cell migration
N0016004molecular_functionphospholipase activator activity
N0016020cellular_componentmembrane
N0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
N0030335biological_processpositive regulation of cell migration
N0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
N0031726molecular_functionCCR1 chemokine receptor binding
N0031729molecular_functionCCR4 chemokine receptor binding
N0031730molecular_functionCCR5 chemokine receptor binding
N0032008biological_processpositive regulation of TOR signaling
N0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
N0034097biological_processresponse to cytokine
N0034112biological_processpositive regulation of homotypic cell-cell adhesion
N0034612biological_processresponse to tumor necrosis factor
N0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
N0042056molecular_functionchemoattractant activity
N0042102biological_processpositive regulation of T cell proliferation
N0042119biological_processneutrophil activation
N0042379molecular_functionchemokine receptor binding
N0042802molecular_functionidentical protein binding
N0042803molecular_functionprotein homodimerization activity
N0043922biological_processhost-mediated suppression of viral transcription
N0044344biological_processcellular response to fibroblast growth factor stimulus
N0045070biological_processpositive regulation of viral genome replication
N0045071biological_processnegative regulation of viral genome replication
N0045089biological_processpositive regulation of innate immune response
N0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
N0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
N0045785biological_processpositive regulation of cell adhesion
N0045948biological_processpositive regulation of translational initiation
N0046817molecular_functionchemokine receptor antagonist activity
N0048020molecular_functionCCR chemokine receptor binding
N0048245biological_processeosinophil chemotaxis
N0048246biological_processmacrophage chemotaxis
N0048661biological_processpositive regulation of smooth muscle cell proliferation
N0050673biological_processepithelial cell proliferation
N0050679biological_processpositive regulation of epithelial cell proliferation
N0050796biological_processregulation of insulin secretion
N0050863biological_processregulation of T cell activation
N0050918biological_processpositive chemotaxis
N0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
N0051928biological_processpositive regulation of calcium ion transport
N0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
N0070098biological_processchemokine-mediated signaling pathway
N0070100biological_processnegative regulation of chemokine-mediated signaling pathway
N0070233biological_processnegative regulation of T cell apoptotic process
N0070234biological_processpositive regulation of T cell apoptotic process
N0071346biological_processcellular response to type II interferon
N0071347biological_processcellular response to interleukin-1
N0071356biological_processcellular response to tumor necrosis factor
N0090026biological_processpositive regulation of monocyte chemotaxis
N0097696biological_processcell surface receptor signaling pathway via STAT
N0098586biological_processcellular response to virus
N0150078biological_processpositive regulation of neuroinflammatory response
N1904894biological_processpositive regulation of receptor signaling pathway via STAT
N2000110biological_processnegative regulation of macrophage apoptotic process
N2000406biological_processpositive regulation of T cell migration
N2000503biological_processpositive regulation of natural killer cell chemotaxis
O0002407biological_processdendritic cell chemotaxis
O0002548biological_processmonocyte chemotaxis
O0002676biological_processregulation of chronic inflammatory response
O0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
O0004672molecular_functionprotein kinase activity
O0005125molecular_functioncytokine activity
O0005515molecular_functionprotein binding
O0005576cellular_componentextracellular region
O0005615cellular_componentextracellular space
O0005737cellular_componentcytoplasm
O0006816biological_processcalcium ion transport
O0006874biological_processintracellular calcium ion homeostasis
O0006887biological_processexocytosis
O0006935biological_processchemotaxis
O0006954biological_processinflammatory response
O0006955biological_processimmune response
O0007159biological_processleukocyte cell-cell adhesion
O0007186biological_processG protein-coupled receptor signaling pathway
O0007267biological_processcell-cell signaling
O0008009molecular_functionchemokine activity
O0009615biological_processresponse to virus
O0009636biological_processresponse to toxic substance
O0010759biological_processpositive regulation of macrophage chemotaxis
O0010820biological_processpositive regulation of T cell chemotaxis
O0014911biological_processpositive regulation of smooth muscle cell migration
O0016004molecular_functionphospholipase activator activity
O0016020cellular_componentmembrane
O0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
O0030335biological_processpositive regulation of cell migration
O0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
O0031726molecular_functionCCR1 chemokine receptor binding
O0031729molecular_functionCCR4 chemokine receptor binding
O0031730molecular_functionCCR5 chemokine receptor binding
O0032008biological_processpositive regulation of TOR signaling
O0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
O0034097biological_processresponse to cytokine
O0034112biological_processpositive regulation of homotypic cell-cell adhesion
O0034612biological_processresponse to tumor necrosis factor
O0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
O0042056molecular_functionchemoattractant activity
O0042102biological_processpositive regulation of T cell proliferation
O0042119biological_processneutrophil activation
O0042379molecular_functionchemokine receptor binding
O0042802molecular_functionidentical protein binding
O0042803molecular_functionprotein homodimerization activity
O0043922biological_processhost-mediated suppression of viral transcription
O0044344biological_processcellular response to fibroblast growth factor stimulus
O0045070biological_processpositive regulation of viral genome replication
O0045071biological_processnegative regulation of viral genome replication
O0045089biological_processpositive regulation of innate immune response
O0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
O0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
O0045785biological_processpositive regulation of cell adhesion
O0045948biological_processpositive regulation of translational initiation
O0046817molecular_functionchemokine receptor antagonist activity
O0048020molecular_functionCCR chemokine receptor binding
O0048245biological_processeosinophil chemotaxis
O0048246biological_processmacrophage chemotaxis
O0048661biological_processpositive regulation of smooth muscle cell proliferation
O0050673biological_processepithelial cell proliferation
O0050679biological_processpositive regulation of epithelial cell proliferation
O0050796biological_processregulation of insulin secretion
O0050863biological_processregulation of T cell activation
O0050918biological_processpositive chemotaxis
O0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
O0051928biological_processpositive regulation of calcium ion transport
O0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
O0070098biological_processchemokine-mediated signaling pathway
O0070100biological_processnegative regulation of chemokine-mediated signaling pathway
O0070233biological_processnegative regulation of T cell apoptotic process
O0070234biological_processpositive regulation of T cell apoptotic process
O0071346biological_processcellular response to type II interferon
O0071347biological_processcellular response to interleukin-1
O0071356biological_processcellular response to tumor necrosis factor
O0090026biological_processpositive regulation of monocyte chemotaxis
O0097696biological_processcell surface receptor signaling pathway via STAT
O0098586biological_processcellular response to virus
O0150078biological_processpositive regulation of neuroinflammatory response
O1904894biological_processpositive regulation of receptor signaling pathway via STAT
O2000110biological_processnegative regulation of macrophage apoptotic process
O2000406biological_processpositive regulation of T cell migration
O2000503biological_processpositive regulation of natural killer cell chemotaxis
P0002407biological_processdendritic cell chemotaxis
P0002548biological_processmonocyte chemotaxis
P0002676biological_processregulation of chronic inflammatory response
P0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
P0004672molecular_functionprotein kinase activity
P0005125molecular_functioncytokine activity
P0005515molecular_functionprotein binding
P0005576cellular_componentextracellular region
P0005615cellular_componentextracellular space
P0005737cellular_componentcytoplasm
P0006816biological_processcalcium ion transport
P0006874biological_processintracellular calcium ion homeostasis
P0006887biological_processexocytosis
P0006935biological_processchemotaxis
P0006954biological_processinflammatory response
P0006955biological_processimmune response
P0007159biological_processleukocyte cell-cell adhesion
P0007186biological_processG protein-coupled receptor signaling pathway
P0007267biological_processcell-cell signaling
P0008009molecular_functionchemokine activity
P0009615biological_processresponse to virus
P0009636biological_processresponse to toxic substance
P0010759biological_processpositive regulation of macrophage chemotaxis
P0010820biological_processpositive regulation of T cell chemotaxis
P0014911biological_processpositive regulation of smooth muscle cell migration
P0016004molecular_functionphospholipase activator activity
P0016020cellular_componentmembrane
P0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
P0030335biological_processpositive regulation of cell migration
P0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
P0031726molecular_functionCCR1 chemokine receptor binding
P0031729molecular_functionCCR4 chemokine receptor binding
P0031730molecular_functionCCR5 chemokine receptor binding
P0032008biological_processpositive regulation of TOR signaling
P0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
P0034097biological_processresponse to cytokine
P0034112biological_processpositive regulation of homotypic cell-cell adhesion
P0034612biological_processresponse to tumor necrosis factor
P0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
P0042056molecular_functionchemoattractant activity
P0042102biological_processpositive regulation of T cell proliferation
P0042119biological_processneutrophil activation
P0042379molecular_functionchemokine receptor binding
P0042802molecular_functionidentical protein binding
P0042803molecular_functionprotein homodimerization activity
P0043922biological_processhost-mediated suppression of viral transcription
P0044344biological_processcellular response to fibroblast growth factor stimulus
P0045070biological_processpositive regulation of viral genome replication
P0045071biological_processnegative regulation of viral genome replication
P0045089biological_processpositive regulation of innate immune response
P0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
P0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
P0045785biological_processpositive regulation of cell adhesion
P0045948biological_processpositive regulation of translational initiation
P0046817molecular_functionchemokine receptor antagonist activity
P0048020molecular_functionCCR chemokine receptor binding
P0048245biological_processeosinophil chemotaxis
P0048246biological_processmacrophage chemotaxis
P0048661biological_processpositive regulation of smooth muscle cell proliferation
P0050673biological_processepithelial cell proliferation
P0050679biological_processpositive regulation of epithelial cell proliferation
P0050796biological_processregulation of insulin secretion
P0050863biological_processregulation of T cell activation
P0050918biological_processpositive chemotaxis
P0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
P0051928biological_processpositive regulation of calcium ion transport
P0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
P0070098biological_processchemokine-mediated signaling pathway
P0070100biological_processnegative regulation of chemokine-mediated signaling pathway
P0070233biological_processnegative regulation of T cell apoptotic process
P0070234biological_processpositive regulation of T cell apoptotic process
P0071346biological_processcellular response to type II interferon
P0071347biological_processcellular response to interleukin-1
P0071356biological_processcellular response to tumor necrosis factor
P0090026biological_processpositive regulation of monocyte chemotaxis
P0097696biological_processcell surface receptor signaling pathway via STAT
P0098586biological_processcellular response to virus
P0150078biological_processpositive regulation of neuroinflammatory response
P1904894biological_processpositive regulation of receptor signaling pathway via STAT
P2000110biological_processnegative regulation of macrophage apoptotic process
P2000406biological_processpositive regulation of T cell migration
P2000503biological_processpositive regulation of natural killer cell chemotaxis
Q0002407biological_processdendritic cell chemotaxis
Q0002548biological_processmonocyte chemotaxis
Q0002676biological_processregulation of chronic inflammatory response
Q0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
Q0004672molecular_functionprotein kinase activity
Q0005125molecular_functioncytokine activity
Q0005515molecular_functionprotein binding
Q0005576cellular_componentextracellular region
Q0005615cellular_componentextracellular space
Q0005737cellular_componentcytoplasm
Q0006816biological_processcalcium ion transport
Q0006874biological_processintracellular calcium ion homeostasis
Q0006887biological_processexocytosis
Q0006935biological_processchemotaxis
Q0006954biological_processinflammatory response
Q0006955biological_processimmune response
Q0007159biological_processleukocyte cell-cell adhesion
Q0007186biological_processG protein-coupled receptor signaling pathway
Q0007267biological_processcell-cell signaling
Q0008009molecular_functionchemokine activity
Q0009615biological_processresponse to virus
Q0009636biological_processresponse to toxic substance
Q0010759biological_processpositive regulation of macrophage chemotaxis
Q0010820biological_processpositive regulation of T cell chemotaxis
Q0014911biological_processpositive regulation of smooth muscle cell migration
Q0016004molecular_functionphospholipase activator activity
Q0016020cellular_componentmembrane
Q0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
Q0030335biological_processpositive regulation of cell migration
Q0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
Q0031726molecular_functionCCR1 chemokine receptor binding
Q0031729molecular_functionCCR4 chemokine receptor binding
Q0031730molecular_functionCCR5 chemokine receptor binding
Q0032008biological_processpositive regulation of TOR signaling
Q0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
Q0034097biological_processresponse to cytokine
Q0034112biological_processpositive regulation of homotypic cell-cell adhesion
Q0034612biological_processresponse to tumor necrosis factor
Q0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
Q0042056molecular_functionchemoattractant activity
Q0042102biological_processpositive regulation of T cell proliferation
Q0042119biological_processneutrophil activation
Q0042379molecular_functionchemokine receptor binding
Q0042802molecular_functionidentical protein binding
Q0042803molecular_functionprotein homodimerization activity
Q0043922biological_processhost-mediated suppression of viral transcription
Q0044344biological_processcellular response to fibroblast growth factor stimulus
Q0045070biological_processpositive regulation of viral genome replication
Q0045071biological_processnegative regulation of viral genome replication
Q0045089biological_processpositive regulation of innate immune response
Q0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
Q0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
Q0045785biological_processpositive regulation of cell adhesion
Q0045948biological_processpositive regulation of translational initiation
Q0046817molecular_functionchemokine receptor antagonist activity
Q0048020molecular_functionCCR chemokine receptor binding
Q0048245biological_processeosinophil chemotaxis
Q0048246biological_processmacrophage chemotaxis
Q0048661biological_processpositive regulation of smooth muscle cell proliferation
Q0050673biological_processepithelial cell proliferation
Q0050679biological_processpositive regulation of epithelial cell proliferation
Q0050796biological_processregulation of insulin secretion
Q0050863biological_processregulation of T cell activation
Q0050918biological_processpositive chemotaxis
Q0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Q0051928biological_processpositive regulation of calcium ion transport
Q0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
Q0070098biological_processchemokine-mediated signaling pathway
Q0070100biological_processnegative regulation of chemokine-mediated signaling pathway
Q0070233biological_processnegative regulation of T cell apoptotic process
Q0070234biological_processpositive regulation of T cell apoptotic process
Q0071346biological_processcellular response to type II interferon
Q0071347biological_processcellular response to interleukin-1
Q0071356biological_processcellular response to tumor necrosis factor
Q0090026biological_processpositive regulation of monocyte chemotaxis
Q0097696biological_processcell surface receptor signaling pathway via STAT
Q0098586biological_processcellular response to virus
Q0150078biological_processpositive regulation of neuroinflammatory response
Q1904894biological_processpositive regulation of receptor signaling pathway via STAT
Q2000110biological_processnegative regulation of macrophage apoptotic process
Q2000406biological_processpositive regulation of T cell migration
Q2000503biological_processpositive regulation of natural killer cell chemotaxis
R0002407biological_processdendritic cell chemotaxis
R0002548biological_processmonocyte chemotaxis
R0002676biological_processregulation of chronic inflammatory response
R0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
R0004672molecular_functionprotein kinase activity
R0005125molecular_functioncytokine activity
R0005515molecular_functionprotein binding
R0005576cellular_componentextracellular region
R0005615cellular_componentextracellular space
R0005737cellular_componentcytoplasm
R0006816biological_processcalcium ion transport
R0006874biological_processintracellular calcium ion homeostasis
R0006887biological_processexocytosis
R0006935biological_processchemotaxis
R0006954biological_processinflammatory response
R0006955biological_processimmune response
R0007159biological_processleukocyte cell-cell adhesion
R0007186biological_processG protein-coupled receptor signaling pathway
R0007267biological_processcell-cell signaling
R0008009molecular_functionchemokine activity
R0009615biological_processresponse to virus
R0009636biological_processresponse to toxic substance
R0010759biological_processpositive regulation of macrophage chemotaxis
R0010820biological_processpositive regulation of T cell chemotaxis
R0014911biological_processpositive regulation of smooth muscle cell migration
R0016004molecular_functionphospholipase activator activity
R0016020cellular_componentmembrane
R0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
R0030335biological_processpositive regulation of cell migration
R0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
R0031726molecular_functionCCR1 chemokine receptor binding
R0031729molecular_functionCCR4 chemokine receptor binding
R0031730molecular_functionCCR5 chemokine receptor binding
R0032008biological_processpositive regulation of TOR signaling
R0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
R0034097biological_processresponse to cytokine
R0034112biological_processpositive regulation of homotypic cell-cell adhesion
R0034612biological_processresponse to tumor necrosis factor
R0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
R0042056molecular_functionchemoattractant activity
R0042102biological_processpositive regulation of T cell proliferation
R0042119biological_processneutrophil activation
R0042379molecular_functionchemokine receptor binding
R0042802molecular_functionidentical protein binding
R0042803molecular_functionprotein homodimerization activity
R0043922biological_processhost-mediated suppression of viral transcription
R0044344biological_processcellular response to fibroblast growth factor stimulus
R0045070biological_processpositive regulation of viral genome replication
R0045071biological_processnegative regulation of viral genome replication
R0045089biological_processpositive regulation of innate immune response
R0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
R0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
R0045785biological_processpositive regulation of cell adhesion
R0045948biological_processpositive regulation of translational initiation
R0046817molecular_functionchemokine receptor antagonist activity
R0048020molecular_functionCCR chemokine receptor binding
R0048245biological_processeosinophil chemotaxis
R0048246biological_processmacrophage chemotaxis
R0048661biological_processpositive regulation of smooth muscle cell proliferation
R0050673biological_processepithelial cell proliferation
R0050679biological_processpositive regulation of epithelial cell proliferation
R0050796biological_processregulation of insulin secretion
R0050863biological_processregulation of T cell activation
R0050918biological_processpositive chemotaxis
R0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
R0051928biological_processpositive regulation of calcium ion transport
R0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
R0070098biological_processchemokine-mediated signaling pathway
R0070100biological_processnegative regulation of chemokine-mediated signaling pathway
R0070233biological_processnegative regulation of T cell apoptotic process
R0070234biological_processpositive regulation of T cell apoptotic process
R0071346biological_processcellular response to type II interferon
R0071347biological_processcellular response to interleukin-1
R0071356biological_processcellular response to tumor necrosis factor
R0090026biological_processpositive regulation of monocyte chemotaxis
R0097696biological_processcell surface receptor signaling pathway via STAT
R0098586biological_processcellular response to virus
R0150078biological_processpositive regulation of neuroinflammatory response
R1904894biological_processpositive regulation of receptor signaling pathway via STAT
R2000110biological_processnegative regulation of macrophage apoptotic process
R2000406biological_processpositive regulation of T cell migration
R2000503biological_processpositive regulation of natural killer cell chemotaxis
S0002407biological_processdendritic cell chemotaxis
S0002548biological_processmonocyte chemotaxis
S0002676biological_processregulation of chronic inflammatory response
S0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
S0004672molecular_functionprotein kinase activity
S0005125molecular_functioncytokine activity
S0005515molecular_functionprotein binding
S0005576cellular_componentextracellular region
S0005615cellular_componentextracellular space
S0005737cellular_componentcytoplasm
S0006816biological_processcalcium ion transport
S0006874biological_processintracellular calcium ion homeostasis
S0006887biological_processexocytosis
S0006935biological_processchemotaxis
S0006954biological_processinflammatory response
S0006955biological_processimmune response
S0007159biological_processleukocyte cell-cell adhesion
S0007186biological_processG protein-coupled receptor signaling pathway
S0007267biological_processcell-cell signaling
S0008009molecular_functionchemokine activity
S0009615biological_processresponse to virus
S0009636biological_processresponse to toxic substance
S0010759biological_processpositive regulation of macrophage chemotaxis
S0010820biological_processpositive regulation of T cell chemotaxis
S0014911biological_processpositive regulation of smooth muscle cell migration
S0016004molecular_functionphospholipase activator activity
S0016020cellular_componentmembrane
S0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
S0030335biological_processpositive regulation of cell migration
S0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
S0031726molecular_functionCCR1 chemokine receptor binding
S0031729molecular_functionCCR4 chemokine receptor binding
S0031730molecular_functionCCR5 chemokine receptor binding
S0032008biological_processpositive regulation of TOR signaling
S0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
S0034097biological_processresponse to cytokine
S0034112biological_processpositive regulation of homotypic cell-cell adhesion
S0034612biological_processresponse to tumor necrosis factor
S0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
S0042056molecular_functionchemoattractant activity
S0042102biological_processpositive regulation of T cell proliferation
S0042119biological_processneutrophil activation
S0042379molecular_functionchemokine receptor binding
S0042802molecular_functionidentical protein binding
S0042803molecular_functionprotein homodimerization activity
S0043922biological_processhost-mediated suppression of viral transcription
S0044344biological_processcellular response to fibroblast growth factor stimulus
S0045070biological_processpositive regulation of viral genome replication
S0045071biological_processnegative regulation of viral genome replication
S0045089biological_processpositive regulation of innate immune response
S0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
S0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
S0045785biological_processpositive regulation of cell adhesion
S0045948biological_processpositive regulation of translational initiation
S0046817molecular_functionchemokine receptor antagonist activity
S0048020molecular_functionCCR chemokine receptor binding
S0048245biological_processeosinophil chemotaxis
S0048246biological_processmacrophage chemotaxis
S0048661biological_processpositive regulation of smooth muscle cell proliferation
S0050673biological_processepithelial cell proliferation
S0050679biological_processpositive regulation of epithelial cell proliferation
S0050796biological_processregulation of insulin secretion
S0050863biological_processregulation of T cell activation
S0050918biological_processpositive chemotaxis
S0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
S0051928biological_processpositive regulation of calcium ion transport
S0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
S0070098biological_processchemokine-mediated signaling pathway
S0070100biological_processnegative regulation of chemokine-mediated signaling pathway
S0070233biological_processnegative regulation of T cell apoptotic process
S0070234biological_processpositive regulation of T cell apoptotic process
S0071346biological_processcellular response to type II interferon
S0071347biological_processcellular response to interleukin-1
S0071356biological_processcellular response to tumor necrosis factor
S0090026biological_processpositive regulation of monocyte chemotaxis
S0097696biological_processcell surface receptor signaling pathway via STAT
S0098586biological_processcellular response to virus
S0150078biological_processpositive regulation of neuroinflammatory response
S1904894biological_processpositive regulation of receptor signaling pathway via STAT
S2000110biological_processnegative regulation of macrophage apoptotic process
S2000406biological_processpositive regulation of T cell migration
S2000503biological_processpositive regulation of natural killer cell chemotaxis
T0002407biological_processdendritic cell chemotaxis
T0002548biological_processmonocyte chemotaxis
T0002676biological_processregulation of chronic inflammatory response
T0004435molecular_functionphosphatidylinositol-4,5-bisphosphate phospholipase C activity
T0004672molecular_functionprotein kinase activity
T0005125molecular_functioncytokine activity
T0005515molecular_functionprotein binding
T0005576cellular_componentextracellular region
T0005615cellular_componentextracellular space
T0005737cellular_componentcytoplasm
T0006816biological_processcalcium ion transport
T0006874biological_processintracellular calcium ion homeostasis
T0006887biological_processexocytosis
T0006935biological_processchemotaxis
T0006954biological_processinflammatory response
T0006955biological_processimmune response
T0007159biological_processleukocyte cell-cell adhesion
T0007186biological_processG protein-coupled receptor signaling pathway
T0007267biological_processcell-cell signaling
T0008009molecular_functionchemokine activity
T0009615biological_processresponse to virus
T0009636biological_processresponse to toxic substance
T0010759biological_processpositive regulation of macrophage chemotaxis
T0010820biological_processpositive regulation of T cell chemotaxis
T0014911biological_processpositive regulation of smooth muscle cell migration
T0016004molecular_functionphospholipase activator activity
T0016020cellular_componentmembrane
T0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
T0030335biological_processpositive regulation of cell migration
T0031583biological_processphospholipase D-activating G protein-coupled receptor signaling pathway
T0031726molecular_functionCCR1 chemokine receptor binding
T0031729molecular_functionCCR4 chemokine receptor binding
T0031730molecular_functionCCR5 chemokine receptor binding
T0032008biological_processpositive regulation of TOR signaling
T0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
T0034097biological_processresponse to cytokine
T0034112biological_processpositive regulation of homotypic cell-cell adhesion
T0034612biological_processresponse to tumor necrosis factor
T0035689biological_processchemokine (C-C motif) ligand 5 signaling pathway
T0042056molecular_functionchemoattractant activity
T0042102biological_processpositive regulation of T cell proliferation
T0042119biological_processneutrophil activation
T0042379molecular_functionchemokine receptor binding
T0042802molecular_functionidentical protein binding
T0042803molecular_functionprotein homodimerization activity
T0043922biological_processhost-mediated suppression of viral transcription
T0044344biological_processcellular response to fibroblast growth factor stimulus
T0045070biological_processpositive regulation of viral genome replication
T0045071biological_processnegative regulation of viral genome replication
T0045089biological_processpositive regulation of innate immune response
T0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
T0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
T0045785biological_processpositive regulation of cell adhesion
T0045948biological_processpositive regulation of translational initiation
T0046817molecular_functionchemokine receptor antagonist activity
T0048020molecular_functionCCR chemokine receptor binding
T0048245biological_processeosinophil chemotaxis
T0048246biological_processmacrophage chemotaxis
T0048661biological_processpositive regulation of smooth muscle cell proliferation
T0050673biological_processepithelial cell proliferation
T0050679biological_processpositive regulation of epithelial cell proliferation
T0050796biological_processregulation of insulin secretion
T0050863biological_processregulation of T cell activation
T0050918biological_processpositive chemotaxis
T0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
T0051928biological_processpositive regulation of calcium ion transport
T0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
T0070098biological_processchemokine-mediated signaling pathway
T0070100biological_processnegative regulation of chemokine-mediated signaling pathway
T0070233biological_processnegative regulation of T cell apoptotic process
T0070234biological_processpositive regulation of T cell apoptotic process
T0071346biological_processcellular response to type II interferon
T0071347biological_processcellular response to interleukin-1
T0071356biological_processcellular response to tumor necrosis factor
T0090026biological_processpositive regulation of monocyte chemotaxis
T0097696biological_processcell surface receptor signaling pathway via STAT
T0098586biological_processcellular response to virus
T0150078biological_processpositive regulation of neuroinflammatory response
T1904894biological_processpositive regulation of receptor signaling pathway via STAT
T2000110biological_processnegative regulation of macrophage apoptotic process
T2000406biological_processpositive regulation of T cell migration
T2000503biological_processpositive regulation of natural killer cell chemotaxis
Functional Information from PROSITE/UniProt
site_idPS00472
Number of Residues42
DetailsSMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCFayiarp..LprahIkeYfytsgk..Csnp.AVVFvtrknrqv.CA
ChainResidueDetails
ACYS10-ALA51

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsModified residue: {"description":"Methionine sulfoxide","evidences":[{"source":"PubMed","id":"1380064","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues11
DetailsGlycosylation: {"description":"O-linked (GalNAc...) serine; partial","evidences":[{"source":"PubMed","id":"1380064","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

244693

PDB entries from 2025-11-12

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