Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | LYS87 |
| A | MET89 |
| A | ILE247 |
| A | THR248 |
| A | ALA249 |
| A | TRP254 |
| A | VAL257 |
| A | TYR258 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | LEU162 |
| A | VAL163 |
| A | ASP164 |
| A | PHE171 |
| A | ILE115 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | GLU66 |
| A | THR88 |
| A | MET89 |
| A | LEU90 |
| A | HOH514 |
| A | HOH598 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | ASP251 |
| A | TRP254 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | TYR142 |
| A | ARG175 |
| A | EDO406 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | GLU138 |
| A | TYR142 |
| A | THR169 |
| A | GLY170 |
| A | PHE171 |
| A | GLU315 |
| A | PRO316 |
| A | VAL317 |
| A | EDO405 |
| A | HOH590 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | binding site for residue EMS A 407 |
| Chain | Residue |
| A | THR17 |
| A | GLU20 |
| A | ALA33 |
| A | HIS34 |
| A | ALA93 |
| A | ALA94 |
| A | SER95 |
| A | PHE119 |
| A | ASN121 |
| A | ASN167 |
| A | ASP198 |
| A | CYS200 |
| A | LYS235 |
| A | LYS243 |
| A | ARG367 |
| A | HOH561 |
| A | HOH580 |
| A | HOH636 |
| A | HOH660 |
| B | THR262 |
| B | SER263 |
| B | VAL264 |
| B | LEU265 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | LYS87 |
| B | MET89 |
| B | ILE247 |
| B | THR248 |
| B | ALA249 |
| B | TRP254 |
| B | VAL257 |
| B | TYR258 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | ILE115 |
| B | PHE141 |
| B | LEU162 |
| B | VAL163 |
| B | ASP164 |
| B | PHE171 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| A | TYR55 |
| A | GLU58 |
| B | ARG38 |
| B | GLN39 |
| B | GLN44 |
| B | HOH519 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | LYS106 |
| B | PRO132 |
| B | LEU133 |
| B | HOH682 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| A | MET129 |
| A | HOH515 |
| B | LYS106 |
| B | MET129 |
| B | HOH503 |
| B | HOH512 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | ASP251 |
| B | TRP254 |
| B | HOH540 |
| B | HOH766 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 407 |
| Chain | Residue |
| B | ARG175 |
| B | GLU315 |
| B | VAL317 |
| B | HOH501 |
| B | HOH544 |
| site_id | AD6 |
| Number of Residues | 24 |
| Details | binding site for residue EMS B 408 |
| Chain | Residue |
| A | LEU265 |
| A | LEU266 |
| A | HOH544 |
| B | THR17 |
| B | GLU20 |
| B | ALA33 |
| B | HIS34 |
| B | ALA93 |
| B | ALA94 |
| B | SER95 |
| B | PHE119 |
| B | ASN121 |
| B | ASN167 |
| B | ASP198 |
| B | CYS200 |
| B | LYS235 |
| B | LYS243 |
| B | ARG367 |
| B | HOH533 |
| B | HOH573 |
| B | HOH657 |
| A | THR262 |
| A | SER263 |
| A | VAL264 |
