6C1C
FGFR1 kinase complex with inhibitor SN37116
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 16 |
| 詳細 | binding site for residue YY6 A 801 |
| 鎖名 | 残基 |
| A | LEU484 |
| A | GLY567 |
| A | ASN568 |
| A | GLU571 |
| A | ALA640 |
| A | ASP641 |
| A | PHE642 |
| A | HOH918 |
| A | VAL492 |
| A | ALA512 |
| A | LYS514 |
| A | GLU531 |
| A | VAL559 |
| A | VAL561 |
| A | GLU562 |
| A | ALA564 |
| site_id | AC2 |
| 残基数 | 11 |
| 詳細 | binding site for residue YY6 B 801 |
| 鎖名 | 残基 |
| B | LEU484 |
| B | LYS514 |
| B | GLU531 |
| B | VAL559 |
| B | VAL561 |
| B | GLU562 |
| B | ALA564 |
| B | GLU571 |
| B | LEU630 |
| B | ALA640 |
| B | ASP641 |
| site_id | AC3 |
| 残基数 | 3 |
| 詳細 | binding site for residue SO4 B 802 |
| 鎖名 | 残基 |
| B | LYS665 |
| B | PRO702 |
| B | GLY703 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10028, ECO:0000269|PubMed:19224897 |
| 鎖名 | 残基 | 詳細 |
| A | ALA625 | |
| B | ALA625 |
| site_id | SWS_FT_FI2 |
| 残基数 | 12 |
| 詳細 | BINDING: |
| 鎖名 | 残基 | 詳細 |
| A | GLU486 | |
| B | ARG570 | |
| B | VAL629 | |
| B | GLY643 | |
| A | LEU516 | |
| A | ALA564 | |
| A | ARG570 | |
| A | VAL629 | |
| A | GLY643 | |
| B | GLU486 | |
| B | LEU516 | |
| B | ALA564 |
| site_id | SWS_FT_FI3 |
| 残基数 | 6 |
| 詳細 | MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16507368, ECO:0000269|PubMed:19224897, ECO:0000269|PubMed:8622701 |
| 鎖名 | 残基 | 詳細 |
| A | LEU465 | |
| A | TYR585 | |
| A | PRO587 | |
| B | LEU465 | |
| B | TYR585 | |
| B | PRO587 |
| site_id | SWS_FT_FI4 |
| 残基数 | 4 |
| 詳細 | MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16507368, ECO:0000269|PubMed:19224897, ECO:0000269|PubMed:19665973, ECO:0000269|PubMed:8622701 |
| 鎖名 | 残基 | 詳細 |
| A | LYS655 | |
| A | LYS656 | |
| B | LYS655 | |
| B | LYS656 |
| site_id | SWS_FT_FI5 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:19224897, ECO:0000269|PubMed:8622701 |
| 鎖名 | 残基 | 詳細 |
| A | MET732 | |
| B | MET732 |
