6C1A

MBD2 in complex with methylated DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
B	0003677	molecular_function	DNA binding
E	0003677	molecular_function	DNA binding
F	0003677	molecular_function	DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for Di-nucleotide DA D 5 and 5CM D 6

Chain	Residue
A	ARG188
D	DT4
D	DA7
D	HOH203
D	HOH205
A	SER189
A	PRO191
A	ARG195
A	HOH409
A	HOH411
C	DG7
C	DT8
C	DA9

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site_id	AC2
Number of Residues	13
Details	binding site for Di-nucleotide 5CM D 6 and DA D 7

Chain	Residue
A	ARG188
A	SER189
A	ARG195
A	HOH411
C	DA5
C	DT6
C	DG7
D	DA5
D	DT8
D	HOH203
D	HOH205
D	HOH206
D	HOH210

---

site_id	AC3
Number of Residues	14
Details	binding site for Di-nucleotide DA H 5 and 5CM H 6

Chain	Residue
E	ARG188
E	SER189
E	LYS190
E	PRO191
E	ARG195
E	HOH409
G	DG7
G	DT8
G	DA9
H	DT4
H	DA7
H	HOH203
H	HOH207
H	HOH211

---

site_id	AC4
Number of Residues	12
Details	binding site for Di-nucleotide 5CM H 6 and DA H 7

Chain	Residue
E	ARG188
E	SER189
E	ARG195
E	HOH409
G	DA5
G	DT6
G	DG7
H	DA5
H	DT8
H	HOH203
H	HOH209
H	HOH211

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER181
B	SER181
E	SER181
F	SER181

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