6BX4
The crystal structure of fluoride channel Fluc Ec2 with Monobody S9
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0062054 | molecular_function | fluoride channel activity |
| A | 0140114 | biological_process | cellular detoxification of fluoride |
| A | 1903424 | biological_process | fluoride transmembrane transport |
| A | 1903425 | molecular_function | fluoride transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0062054 | molecular_function | fluoride channel activity |
| B | 0140114 | biological_process | cellular detoxification of fluoride |
| B | 1903424 | biological_process | fluoride transmembrane transport |
| B | 1903425 | molecular_function | fluoride transmembrane transporter activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue F A 201 |
| Chain | Residue |
| A | ASN41 |
| A | GLY45 |
| A | SER110 |
| B | PHE80 |
| B | SER81 |
| B | SER84 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue F A 202 |
| Chain | Residue |
| A | PHE83 |
| A | GLU86 |
| A | HOH318 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue DMU A 203 |
| Chain | Residue |
| A | PHE88 |
| A | LEU91 |
| A | GLN92 |
| A | GLY94 |
| A | TYR96 |
| A | HOH313 |
| B | LEU111 |
| B | PHE119 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 204 |
| Chain | Residue |
| A | GLY75 |
| A | SER78 |
| B | GLY75 |
| B | SER78 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue F B 201 |
| Chain | Residue |
| A | PHE80 |
| A | SER81 |
| B | ASN41 |
| B | GLY45 |
| B | SER110 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue F B 202 |
| Chain | Residue |
| B | PHE83 |
| B | GLU86 |
| B | VAL87 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue DMU B 203 |
| Chain | Residue |
| A | ILE108 |
| A | LEU111 |
| A | ILE112 |
| A | PHE119 |
| B | LEU91 |
| B | GLN92 |
| B | GLY94 |
| B | TYR96 |
| B | HOH301 |
| B | HOH306 |
| B | HOH314 |
| D | PRO52 |
Functional Information from PROSITE/UniProt
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETGGNSP |
| Chain | Residue | Details |
| C | GLY38-PRO45 |
