6BX3
Structure of histone H3k4 methyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0000781 | cellular_component | chromosome, telomeric region |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0031509 | biological_process | subtelomeric heterochromatin formation |
| A | 0042393 | molecular_function | histone binding |
| A | 0042800 | molecular_function | histone H3K4 methyltransferase activity |
| A | 0048188 | cellular_component | Set1C/COMPASS complex |
| A | 1903341 | biological_process | regulation of meiotic DNA double-strand break formation |
| A | 1990234 | cellular_component | transferase complex |
| B | 0000723 | biological_process | telomere maintenance |
| B | 0000781 | cellular_component | chromosome, telomeric region |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0031509 | biological_process | subtelomeric heterochromatin formation |
| B | 0042800 | molecular_function | histone H3K4 methyltransferase activity |
| B | 0048188 | cellular_component | Set1C/COMPASS complex |
| E | 0042800 | molecular_function | histone H3K4 methyltransferase activity |
| K | 0048188 | cellular_component | Set1C/COMPASS complex |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LFTSsmDeSIKIWDT |
| Chain | Residue | Details |
| A | LEU111-THR125 | |
| B | LEU87-LEU101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31253666","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J2P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 79 |
| Details | Repeat: {"description":"WD 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 81 |
| Details | Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31922488","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6VEN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 30 |
| Details | Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
