6BWF
4.1 angstrom Mg2+-unbound structure of mouse TRPM7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0051262 | biological_process | protein tetramerization |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0051262 | biological_process | protein tetramerization |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0051262 | biological_process | protein tetramerization |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0051262 | biological_process | protein tetramerization |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 100 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | ALA505-VAL530 | |
| B | ALA505-VAL530 | |
| C | ALA505-VAL530 | |
| D | ALA505-VAL530 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 80 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | LYS531-PRO536 | |
| C | GLY598-HIS610 | |
| C | PRO678-HIS679 | |
| C | GLY721-GLY723 | |
| D | LYS531-PRO536 | |
| D | GLY598-HIS610 | |
| D | PRO678-HIS679 | |
| D | GLY721-GLY723 | |
| A | GLY598-HIS610 | |
| A | PRO678-HIS679 | |
| A | GLY721-GLY723 | |
| B | LYS531-PRO536 | |
| B | GLY598-HIS610 | |
| B | PRO678-HIS679 | |
| B | GLY721-GLY723 | |
| C | LYS531-PRO536 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | SER537-VAL558 | |
| B | SER537-VAL558 | |
| C | SER537-VAL558 | |
| D | SER537-VAL558 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 144 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | PHE559-TYR577 | |
| A | ALA635-ASN653 | |
| B | PHE559-TYR577 | |
| B | ALA635-ASN653 | |
| C | PHE559-TYR577 | |
| C | ALA635-ASN653 | |
| D | PHE559-TYR577 | |
| D | ALA635-ASN653 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 76 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | PHE578-PHE597 | |
| B | PHE578-PHE597 | |
| C | PHE578-PHE597 | |
| D | PHE578-PHE597 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 92 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | VAL611-LEU634 | |
| B | VAL611-LEU634 | |
| C | VAL611-LEU634 | |
| D | VAL611-LEU634 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 92 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | MET654-TYR677 | |
| B | MET654-TYR677 | |
| C | MET654-TYR677 | |
| D | MET654-TYR677 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 160 |
| Details | INTRAMEM: Pore-forming => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | GLU680-CYS720 | |
| B | GLU680-CYS720 | |
| C | GLU680-CYS720 | |
| D | GLU680-CYS720 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 112 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:37156763, ECO:0007744|PDB:8SI2 |
| Chain | Residue | Details |
| A | THR724-ASN752 | |
| B | THR724-ASN752 | |
| C | THR724-ASN752 | |
| D | THR724-ASN752 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q96QT4 |
| Chain | Residue | Details |
| A | THR817 | |
| A | THR919 | |
| B | THR817 | |
| B | THR919 | |
| C | THR817 | |
| C | THR919 | |
| D | THR817 | |
| D | THR919 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q96QT4 |
| Chain | Residue | Details |
| A | SER845 | |
| D | SER845 | |
| D | SER847 | |
| D | SER912 | |
| A | SER847 | |
| A | SER912 | |
| B | SER845 | |
| B | SER847 | |
| B | SER912 | |
| C | SER845 | |
| C | SER847 | |
| C | SER912 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:22222377 |
| Chain | Residue | Details |
| A | SER878 | |
| A | SER954 | |
| B | SER878 | |
| B | SER954 | |
| C | SER878 | |
| C | SER954 | |
| D | SER878 | |
| D | SER954 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | SER909 | |
| B | SER909 | |
| C | SER909 | |
| D | SER909 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 12 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q96QT4 |
| Chain | Residue | Details |
| A | CYS797 | |
| D | CYS797 | |
| D | CYS798 | |
| D | CYS800 | |
| A | CYS798 | |
| A | CYS800 | |
| B | CYS797 | |
| B | CYS798 | |
| B | CYS800 | |
| C | CYS797 | |
| C | CYS798 | |
| C | CYS800 |
