Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6BWD

3.7 angstrom cryoEM structure of truncated mouse TRPM7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0051262	biological_process	protein tetramerization
A	0055085	biological_process	transmembrane transport
B	0005216	molecular_function	monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0051262	biological_process	protein tetramerization
B	0055085	biological_process	transmembrane transport
C	0005216	molecular_function	monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0051262	biological_process	protein tetramerization
C	0055085	biological_process	transmembrane transport
D	0005216	molecular_function	monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0051262	biological_process	protein tetramerization
D	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue MG A 1201

Chain	Residue
A	GLU885
A	HOH1304
B	GLU885
B	HOH1301
C	HOH1404
D	HOH1303
D	HOH1305
D	HOH1308

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 1202

Chain	Residue
B	HOH1304
C	TYR740
C	HOH1402
C	HOH1405
D	TYR923
D	HOH1304
A	HOH1302

site_id	AC3
Number of Residues	7
Details	binding site for residue Y01 A 1203

Chain	Residue
A	TYR597
A	PHE694
A	TRP695
A	PHE817
A	LEU818
A	ASN821
A	Y011208

site_id	AC4
Number of Residues	4
Details	binding site for residue Y01 A 1204

Chain	Residue
A	MET706
A	PHE710
A	GLN723
A	Y011208

site_id	AC5
Number of Residues	10
Details	binding site for residue Y01 A 1205

Chain	Residue
A	LEU850
A	PRO866
A	TRP868
A	ALA871
B	LEU702
B	MET706
B	THR709
B	PHE710
B	TYR811
B	Y011204

site_id	AC6
Number of Residues	9
Details	binding site for residue Y01 A 1206

Chain	Residue
A	PHE762
A	LEU815
A	VAL828
A	MET829
A	GLY832
A	Y011207
D	SER851
D	PHE852
D	VAL917

site_id	AC7
Number of Residues	4
Details	binding site for residue Y01 A 1207

Chain	Residue
A	TYR761
A	SER765
A	PHE809
A	Y011206

site_id	AC8
Number of Residues	7
Details	binding site for residue Y01 A 1208

Chain	Residue
A	MET706
A	TYR811
A	Y011203
A	Y011204
D	PRO866
D	TRP868
D	LEU870

site_id	AC9
Number of Residues	3
Details	binding site for residue MG B 1201

Chain	Residue
B	HOH1302
D	HOH1301
D	HOH1308

site_id	AD1
Number of Residues	6
Details	binding site for residue MG B 1202

Chain	Residue
A	HOH1303
B	HOH1303
B	HOH1306
C	HOH1403
D	HOH1302
D	HOH1309

site_id	AD2
Number of Residues	5
Details	binding site for residue Y01 B 1203

Chain	Residue
A	PRO866
B	MET706
B	LEU707
B	PHE710
B	GLN723

site_id	AD3
Number of Residues	9
Details	binding site for residue Y01 B 1204

Chain	Residue
A	LEU850
A	Y011205
B	TYR597
B	PHE694
B	TRP695
B	LEU702
B	PHE817
B	LEU818
B	ASN821

site_id	AD4
Number of Residues	10
Details	binding site for residue Y01 B 1205

Chain	Residue
A	SER851
A	LEU914
A	VAL917
B	TYR761
B	PHE762
B	VAL812
B	VAL828
B	MET829
B	GLN952
B	Y011206

site_id	AD5
Number of Residues	4
Details	binding site for residue Y01 B 1206

Chain	Residue
B	TYR761
B	SER765
B	PHE809
B	Y011205

site_id	AD6
Number of Residues	6
Details	binding site for residue Y01 C 1301

Chain	Residue
C	GLY520
C	MET523
C	LEU524
C	PHE527
C	GLN540
C	Y011302

site_id	AD7
Number of Residues	5
Details	binding site for residue Y01 C 1302

Chain	Residue
B	PRO866
B	ILE874
C	LEU522
C	TYR628
C	Y011301

site_id	AD8
Number of Residues	8
Details	binding site for residue Y01 C 1303

Chain	Residue
B	LEU850
C	TYR414
C	PHE511
C	TRP512
C	PHE634
C	LEU635
C	VAL637
C	ASN638

site_id	AD9
Number of Residues	7
Details	binding site for residue Y01 C 1304

Chain	Residue
C	PRO683
C	TRP685
C	Y011305
D	MET706
D	THR709
D	PHE710
D	Y011202

site_id	AE1
Number of Residues	6
Details	binding site for residue Y01 C 1305

Chain	Residue
C	LEU667
C	Y011304
D	PHE694
D	TRP695
D	PHE817
D	VAL820

site_id	AE2
Number of Residues	10
Details	binding site for residue Y01 C 1306

Chain	Residue
B	SER851
B	PHE852
C	TYR578
C	PHE579
C	LEU632
C	VAL645
C	MET646
C	GLY649
C	GLN769
C	Y011307

site_id	AE3
Number of Residues	4
Details	binding site for residue Y01 C 1307

Chain	Residue
C	TYR578
C	ILE625
C	PHE626
C	Y011306

site_id	AE4
Number of Residues	10
Details	binding site for residue Y01 C 1308

Chain	Residue
C	SER668
C	PHE669
C	LEU731
D	PHE762
D	ILE808
D	VAL812
D	LEU815
D	VAL828
D	GLN952
D	Y011203

site_id	AE5
Number of Residues	3
Details	binding site for residue MG D 1201

Chain	Residue
B	PHE883
C	HOH1402
D	HOH1307

site_id	AE6
Number of Residues	4
Details	binding site for residue Y01 D 1202

Chain	Residue
C	Y011304
D	GLY703
D	PHE710
D	GLN723

site_id	AE7
Number of Residues	6
Details	binding site for residue Y01 D 1203

Chain	Residue
C	LEU731
C	Y011308
D	TYR761
D	ILE808
D	PHE809
D	VAL812

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	44
Details	Compositional bias: {"description":"Low complexity","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	52
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)