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6BVR

Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans

Functional Information from GO Data
ChainGOidnamespacecontents
A0000334molecular_function3-hydroxyanthranilate 3,4-dioxygenase activity
A0005506molecular_functioniron ion binding
A0006569biological_processtryptophan catabolic process
A0008198molecular_functionferrous iron binding
A0009435biological_processNAD biosynthetic process
A0019363biological_processpyridine nucleotide biosynthetic process
A0019805biological_processquinolinate biosynthetic process
A0034354biological_process'de novo' NAD biosynthetic process from tryptophan
A0043420biological_processanthranilate metabolic process
A0046872molecular_functionmetal ion binding
A0051213molecular_functiondioxygenase activity
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue TRS A 201
ChainResidue
AVAL132
AHIS133
AASP158
ALYS159
AARG161
APRO163
AHOH309
AHOH347

site_idAC2
Number of Residues5
Detailsbinding site for residue FE2 A 202
ChainResidue
AGLU57
AHIS95
AHOH307
AHOH440
AHIS51

site_idAC3
Number of Residues4
Detailsbinding site for residue FE2 A 203
ChainResidue
ACYS125
ACYS128
ACYS162
ACYS165

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBINDING:
ChainResidueDetails
AARG47
ACYS165
AHIS51
AGLU57
AHIS95
AARG99
AGLU110
ACYS125
ACYS128
ACYS162

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PDB entries from 2024-10-30

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