Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SCN A 301 |
| Chain | Residue |
| A | HIS93 |
| A | ARG182 |
| A | E8S305 |
| A | HOH531 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SCN A 302 |
| Chain | Residue |
| A | HOH540 |
| B | ARG112 |
| A | GLY160 |
| A | ILE161 |
| A | PHE162 |
| A | LEU163 |
| A | HOH427 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 303 |
| Chain | Residue |
| A | HIS93 |
| A | HIS97 |
| A | HIS103 |
| A | E8S305 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 304 |
| Chain | Residue |
| A | ACE-1 |
| A | GLU104 |
| A | GLN192 |
| A | HOH481 |
| A | HOH489 |
| A | HOH513 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue E8S A 305 |
| Chain | Residue |
| A | GLY64 |
| A | CYS65 |
| A | HIS93 |
| A | GLU94 |
| A | HIS97 |
| A | HIS103 |
| A | ASN128 |
| A | TYR152 |
| A | THR156 |
| A | ARG182 |
| A | SCN301 |
| A | ZN303 |
| A | EDO306 |
| A | HOH411 |
| A | HOH483 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | CYS66 |
| A | SER67 |
| A | VAL69 |
| A | HIS97 |
| A | HIS103 |
| A | E8S305 |
| A | HOH419 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SCN B 301 |
| Chain | Residue |
| A | ARG110 |
| A | ILE116 |
| A | ARG118 |
| B | PHE162 |
| B | HOH486 |
| B | HOH532 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SCN B 302 |
| Chain | Residue |
| B | LEU140 |
| B | HOH466 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 303 |
| Chain | Residue |
| B | ACE-1 |
| B | GLU104 |
| B | GLN192 |
| B | HOH472 |
| B | HOH503 |
| B | HOH522 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 304 |
| Chain | Residue |
| B | HIS93 |
| B | HIS97 |
| B | HIS103 |
| B | HOH408 |
| B | HOH488 |
| B | HOH546 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | TRP10 |
| B | ASP53 |
| B | SER54 |
| B | ARG71 |
| B | HOH406 |
| B | HOH525 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 306 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| A | ARG32 |
| B | PHE17 |
| B | PHE46 |
| B | HOH524 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide ACE B -1 and ALA B 1 |
| Chain | Residue |
| B | ALA2 |
| B | THR3 |
| B | PHE101 |
| B | TRP102 |
| B | HIS103 |
| B | GLU104 |
| B | ARG107 |
| B | SER139 |
| B | GLN192 |
| B | ZN303 |
| B | HOH439 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. IVVHELGHVV |
| Chain | Residue | Details |
| A | ILE90-VAL99 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU94 | |
| B | GLU94 | |
| Chain | Residue | Details |
| A | HIS93 | |
| A | HIS97 | |
| A | HIS103 | |
| B | HIS93 | |
| B | HIS97 | |
| B | HIS103 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN22 | |
| B | ASN22 | |
