6BTQ

BMP1 complexed with a hydroxamate - compound 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
B	0004222	molecular_function	metalloendopeptidase activity
B	0006508	biological_process	proteolysis
B	0008237	molecular_function	metallopeptidase activity
B	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SCN A 301

Chain	Residue
A	HIS93
A	ARG182
A	E8S305
A	HOH531

---

site_id	AC2
Number of Residues	7
Details	binding site for residue SCN A 302

Chain	Residue
A	HOH540
B	ARG112
A	GLY160
A	ILE161
A	PHE162
A	LEU163
A	HOH427

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 303

Chain	Residue
A	HIS93
A	HIS97
A	HIS103
A	E8S305

---

site_id	AC4
Number of Residues	6
Details	binding site for residue ZN A 304

Chain	Residue
A	ACE-1
A	GLU104
A	GLN192
A	HOH481
A	HOH489
A	HOH513

---

site_id	AC5
Number of Residues	15
Details	binding site for residue E8S A 305

Chain	Residue
A	GLY64
A	CYS65
A	HIS93
A	GLU94
A	HIS97
A	HIS103
A	ASN128
A	TYR152
A	THR156
A	ARG182
A	SCN301
A	ZN303
A	EDO306
A	HOH411
A	HOH483

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO A 306

Chain	Residue
A	CYS66
A	SER67
A	VAL69
A	HIS97
A	HIS103
A	E8S305
A	HOH419

---

site_id	AC7
Number of Residues	6
Details	binding site for residue SCN B 301

Chain	Residue
A	ARG110
A	ILE116
A	ARG118
B	PHE162
B	HOH486
B	HOH532

---

site_id	AC8
Number of Residues	2
Details	binding site for residue SCN B 302

Chain	Residue
B	LEU140
B	HOH466

---

site_id	AC9
Number of Residues	6
Details	binding site for residue ZN B 303

Chain	Residue
B	ACE-1
B	GLU104
B	GLN192
B	HOH472
B	HOH503
B	HOH522

---

site_id	AD1
Number of Residues	6
Details	binding site for residue ZN B 304

Chain	Residue
B	HIS93
B	HIS97
B	HIS103
B	HOH408
B	HOH488
B	HOH546

---

site_id	AD2
Number of Residues	6
Details	binding site for residue EDO B 305

Chain	Residue
B	TRP10
B	ASP53
B	SER54
B	ARG71
B	HOH406
B	HOH525

---

site_id	AD3
Number of Residues	2
Details	binding site for residue EDO B 306

Chain	Residue
B	PRO11
B	ASP12

---

site_id	AD4
Number of Residues	4
Details	binding site for residue EDO B 307

Chain	Residue
A	ARG32
B	PHE17
B	PHE46
B	HOH524

---

site_id	AD5
Number of Residues	11
Details	binding site for Di-peptide ACE B -1 and ALA B 1

Chain	Residue
B	ALA2
B	THR3
B	PHE101
B	TRP102
B	HIS103
B	GLU104
B	ARG107
B	SER139
B	GLN192
B	ZN303
B	HOH439

---

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. IVVHELGHVV

Chain	Residue	Details
A	ILE90-VAL99

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01211","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18824173","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01211","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18824173","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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