6BTI
Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001523 | biological_process | retinoid metabolic process |
| A | 0005501 | molecular_function | retinoid binding |
| A | 0005504 | molecular_function | fatty acid binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006776 | biological_process | vitamin A metabolic process |
| A | 0008289 | molecular_function | lipid binding |
| A | 0008544 | biological_process | epidermis development |
| A | 0015908 | biological_process | fatty acid transport |
| A | 0016918 | molecular_function | retinal binding |
| A | 0019841 | molecular_function | retinol binding |
| A | 0044325 | molecular_function | transmembrane transporter binding |
| A | 0098681 | cellular_component | synaptic ribbon |
| A | 0140104 | molecular_function | molecular carrier activity |
| A | 1904768 | molecular_function | all-trans-retinol binding |
| B | 0001523 | biological_process | retinoid metabolic process |
| B | 0005501 | molecular_function | retinoid binding |
| B | 0005504 | molecular_function | fatty acid binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006776 | biological_process | vitamin A metabolic process |
| B | 0008289 | molecular_function | lipid binding |
| B | 0008544 | biological_process | epidermis development |
| B | 0015908 | biological_process | fatty acid transport |
| B | 0016918 | molecular_function | retinal binding |
| B | 0019841 | molecular_function | retinol binding |
| B | 0044325 | molecular_function | transmembrane transporter binding |
| B | 0098681 | cellular_component | synaptic ribbon |
| B | 0140104 | molecular_function | molecular carrier activity |
| B | 1904768 | molecular_function | all-trans-retinol binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue E7Y A 201 |
| Chain | Residue |
| A | PHE16 |
| A | THR53 |
| A | SER55 |
| A | ARG58 |
| A | TYR60 |
| A | VAL62 |
| A | LEU77 |
| A | TRP106 |
| A | GLN108 |
| A | LEU117 |
| A | HOH363 |
| A | TYR19 |
| A | MET20 |
| A | LEU23 |
| A | ILE25 |
| A | ALA33 |
| A | GLN38 |
| A | LYS40 |
| A | THR51 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 202 |
| Chain | Residue |
| A | ASP61 |
| A | VAL62 |
| A | ASP63 |
| A | ASP71 |
| A | HOH302 |
| A | HOH372 |
| A | HOH382 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 203 |
| Chain | Residue |
| A | ARG2 |
| A | GLN44 |
| A | ASP45 |
| A | GLY46 |
| A | HOH326 |
| A | HOH337 |
| A | HOH438 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue E7Y B 201 |
| Chain | Residue |
| B | PHE16 |
| B | TYR19 |
| B | MET20 |
| B | ALA33 |
| B | LYS40 |
| B | THR51 |
| B | THR53 |
| B | ARG58 |
| B | VAL62 |
| B | LEU77 |
| B | TRP106 |
| B | GLN108 |
| B | HOH305 |
| B | HOH309 |
| B | HOH318 |
| B | HOH349 |
| B | HOH453 |
Functional Information from PROSITE/UniProt
| site_id | PS00214 |
| Number of Residues | 18 |
| Details | FABP Cytosolic fatty-acid binding proteins signature. GTWeMesNeNFEgYMKAL |
| Chain | Residue | Details |
| A | GLY6-LEU23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18076076","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
