Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue EFZ A 601 |
| Chain | Residue |
| A | LEU100 |
| A | HIS235 |
| A | LYS101 |
| A | LYS103 |
| A | VAL106 |
| A | TYR181 |
| A | TYR188 |
| A | GLY190 |
| A | TRP229 |
| A | LEU234 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 602 |
| Chain | Residue |
| A | ASP443 |
| A | GLU478 |
| A | ASP498 |
| A | CA603 |
| R | C24 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 603 |
| Chain | Residue |
| A | ASP443 |
| A | GLY444 |
| A | ASP549 |
| A | CA602 |
| R | A25 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 604 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| B | ASN265 |
| B | GLN269 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | GLU53 |
| B | TYR56 |
| B | LYS126 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 101 |
| Chain | Residue |
| D | DT18 |
| D | DG19 |
| R | C8 |
| R | C9 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue PEG R 101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"RT 'primer grip'","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Tryptophan repeat motif","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12206668","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 175 |
