6BQO
Structure of a dual topology fluoride channel with monobody S8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0062054 | molecular_function | fluoride channel activity |
| A | 0140114 | biological_process | cellular detoxification of fluoride |
| A | 1903424 | biological_process | fluoride transmembrane transport |
| A | 1903425 | molecular_function | fluoride transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0062054 | molecular_function | fluoride channel activity |
| B | 0140114 | biological_process | cellular detoxification of fluoride |
| B | 1903424 | biological_process | fluoride transmembrane transport |
| B | 1903425 | molecular_function | fluoride transmembrane transporter activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue F A 201 |
| Chain | Residue |
| A | ASN43 |
| A | PHE85 |
| A | TYR104 |
| A | SER108 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 202 |
| Chain | Residue |
| A | GLY77 |
| A | THR80 |
| A | THR81 |
| B | GLY77 |
| B | THR80 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue OLC B 202 |
| Chain | Residue |
| B | TRP63 |
| B | ILE67 |
| C | LYS8 |
| C | ASP24 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue F B 203 |
| Chain | Residue |
| A | PHE82 |
| A | SER83 |
| B | ASN43 |
| B | GLY47 |
| B | SER112 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue OLC C 101 |
| Chain | Residue |
| A | ASP91 |
| B | HOH301 |
| C | ILE83 |
| C | TYR84 |
| C | SER86 |
| C | HIS88 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 200 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:26344196, ECO:0007744|PDB:5A40, ECO:0007744|PDB:5NKQ |
| Chain | Residue | Details |
| A | LEU7-LYS29 | |
| A | PRO36-ILE57 | |
| A | ALA65-CYS94 | |
| A | TYR98-LEU126 | |
| B | LEU7-LYS29 | |
| B | PRO36-ILE57 | |
| B | ALA65-CYS94 | |
| B | TYR98-LEU126 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26344196, ECO:0007744|PDB:5NKQ |
| Chain | Residue | Details |
| A | ASN43 | |
| A | TYR104 | |
| A | SER108 | |
| A | SER112 | |
| B | ASN43 | |
| B | TYR104 | |
| B | SER108 | |
| B | SER112 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00454, ECO:0000269|PubMed:26344196, ECO:0007744|PDB:5NKQ |
| Chain | Residue | Details |
| A | GLY77 | |
| A | THR80 | |
| B | GLY77 | |
| B | THR80 |
