6BP8
Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0008283 | biological_process | cell population proliferation |
| A | 0016032 | biological_process | viral process |
| A | 0019901 | molecular_function | protein kinase binding |
| A | 0019903 | molecular_function | protein phosphatase binding |
| A | 0031953 | biological_process | negative regulation of protein autophosphorylation |
| A | 0038127 | biological_process | ERBB signaling pathway |
| A | 0042059 | biological_process | negative regulation of epidermal growth factor receptor signaling pathway |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| A | 0072376 | biological_process | protein activation cascade |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKNGDKVMAgdEW |
| Chain | Residue | Details |
| A | ASP131-TRP143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:Q14764 |
| Chain | Residue | Details |
| A | ALA2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903 |
| Chain | Residue | Details |
| A | SER421 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:Q14764 |
| Chain | Residue | Details |
| A | LYS444 | |
| A | LYS704 |
