6BO5
TRPV2 ion channel in partially closed state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 96 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 136 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 72 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 180 |
| Details | Repeat: {"description":"ANK 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00023","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16809337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 140 |
| Details | Repeat: {"description":"ANK 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00023","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16809337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 192 |
| Details | Repeat: {"description":"ANK 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00023","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16809337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 132 |
| Details | Repeat: {"description":"ANK 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00023","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16809337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39972168","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9B3U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B3Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
