Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 5OD A 601 |
| Chain | Residue |
| A | THR108 |
| A | THR253 |
| A | LEU254 |
| A | GLN257 |
| A | PRO491 |
| A | LYS492 |
| A | GLN495 |
| A | HOH843 |
| A | GLU110 |
| A | ARG111 |
| A | PHE113 |
| A | HIS114 |
| A | THR218 |
| A | THR219 |
| A | GLU249 |
| A | GLU250 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue DZS A 602 |
| Chain | Residue |
| A | GLN79 |
| A | TYR80 |
| A | GLU83 |
| A | HIS84 |
| A | LEU262 |
| A | TYR263 |
| A | SER264 |
| A | ARG265 |
| A | LYS266 |
| A | GLN269 |
| A | ASN281 |
| A | HOH810 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 603 |
| Chain | Residue |
| A | ARG111 |
| A | GLU195 |
| A | GLN257 |
| A | LYS260 |
| A | HOH724 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 604 |
| Chain | Residue |
| A | ARG32 |
| A | SER34 |
| A | LYS35 |
| A | THR42 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue 5OD B 601 |
| Chain | Residue |
| B | THR108 |
| B | GLU110 |
| B | ARG111 |
| B | PHE113 |
| B | THR218 |
| B | THR219 |
| B | GLU249 |
| B | GLU250 |
| B | THR253 |
| B | LEU254 |
| B | GLN257 |
| B | PRO491 |
| B | LYS492 |
| B | GLN495 |
| B | HOH812 |
| B | HOH815 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue DZS B 602 |
| Chain | Residue |
| B | GLN79 |
| B | TYR80 |
| B | GLU83 |
| B | HIS84 |
| B | LEU262 |
| B | TYR263 |
| B | SER264 |
| B | ARG265 |
| B | LYS266 |
| B | GLN269 |
| B | ASN281 |
| B | LEU283 |
| B | HOH744 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 603 |
| Chain | Residue |
| B | ARG32 |
| B | SER34 |
| B | LYS35 |
| B | SER36 |
| B | THR42 |
| B | HOH765 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 B 604 |
| Chain | Residue |
| B | PHE346 |
| B | ASN349 |
| B | ARG413 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| A | GLY407 |
| B | SER391 |
| B | ALA392 |
| B | ALA393 |
| B | TYR396 |
| B | LEU398 |
| B | HOH707 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P35235","evidenceCode":"ECO:0000250"}]} |
