Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue DZS A 601 |
| Chain | Residue |
| A | GLN79 |
| A | GLN269 |
| A | ASN281 |
| A | HOH900 |
| A | TYR80 |
| A | GLU83 |
| A | HIS84 |
| A | LEU262 |
| A | TYR263 |
| A | SER264 |
| A | ARG265 |
| A | LYS266 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 602 |
| Chain | Residue |
| A | ARG32 |
| A | SER34 |
| A | LYS35 |
| A | SER36 |
| A | THR42 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 603 |
| Chain | Residue |
| A | ASP61 |
| A | TYR62 |
| A | ARG278 |
| A | TYR279 |
| A | SER365 |
| A | LYS366 |
| A | SER460 |
| A | HOH803 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 604 |
| Chain | Residue |
| A | LYS131 |
| A | ASN217 |
| A | ARG220 |
| A | LYS492 |
| A | HOH795 |
| A | HOH905 |
| A | HOH920 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue DZS B 601 |
| Chain | Residue |
| B | GLN79 |
| B | TYR80 |
| B | GLU83 |
| B | HIS84 |
| B | LEU262 |
| B | TYR263 |
| B | SER264 |
| B | ARG265 |
| B | LYS266 |
| B | GLN269 |
| B | ASN281 |
| B | HOH759 |
| B | HOH797 |
| B | HOH914 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 602 |
| Chain | Residue |
| B | ARG32 |
| B | SER34 |
| B | LYS35 |
| B | SER36 |
| B | THR42 |
| B | HOH716 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P35235","evidenceCode":"ECO:0000250"}]} |
