6BMS

Palmitoyltransferase structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0005783	cellular_component	endoplasmic reticulum
A	0005794	cellular_component	Golgi apparatus
A	0006612	biological_process	protein targeting to membrane
A	0008270	molecular_function	zinc ion binding
A	0014069	cellular_component	postsynaptic density
A	0016188	biological_process	synaptic vesicle maturation
A	0016409	molecular_function	palmitoyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0019705	molecular_function	protein-cysteine S-myristoyltransferase activity
A	0019706	molecular_function	protein-cysteine S-palmitoyltransferase activity
A	0046872	molecular_function	metal ion binding
A	0072657	biological_process	protein localization to membrane
A	0140439	molecular_function	protein-cysteine S-stearoyltransferase activity
A	0140450	biological_process	protein targeting to Golgi apparatus
D	0000139	cellular_component	Golgi membrane
D	0005783	cellular_component	endoplasmic reticulum
D	0005794	cellular_component	Golgi apparatus
D	0006612	biological_process	protein targeting to membrane
D	0008270	molecular_function	zinc ion binding
D	0014069	cellular_component	postsynaptic density
D	0016188	biological_process	synaptic vesicle maturation
D	0016409	molecular_function	palmitoyltransferase activity
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0019705	molecular_function	protein-cysteine S-myristoyltransferase activity
D	0019706	molecular_function	protein-cysteine S-palmitoyltransferase activity
D	0046872	molecular_function	metal ion binding
D	0072657	biological_process	protein localization to membrane
D	0140439	molecular_function	protein-cysteine S-stearoyltransferase activity
D	0140450	biological_process	protein targeting to Golgi apparatus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1001

Chain	Residue
A	CYS115
A	CYS118
A	HIS128
A	CYS135

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1002

Chain	Residue
A	CYS129
A	CYS132
A	HIS142
A	CYS149

---

site_id	AC3
Number of Residues	7
Details	binding site for residue LMT A 1003

Chain	Residue
A	LEU229
A	PHE232
A	HOH1115
D	ALA197
D	HIS200
D	LMT1003
A	THR228

---

site_id	AC4
Number of Residues	3
Details	binding site for residue LMT A 1004

Chain	Residue
A	PHE195
A	HIS196
D	THR232

---

site_id	AC5
Number of Residues	6
Details	binding site for residue LMT A 1005

Chain	Residue
A	HIS196
D	HIS145
D	HIS146
D	TRP149
D	SER167
D	PLM1004

---

site_id	AC6
Number of Residues	12
Details	binding site for residue PLM A 1006

Chain	Residue
A	VAL18
A	PHE55
A	HIS141
A	SER143
A	TRP145
A	PHE158
A	PHE161
A	VAL203
A	PHE207
A	LEU214
A	HOH1108
D	LMT1003

---

site_id	AC7
Number of Residues	8
Details	binding site for residue POV A 1007

Chain	Residue
A	GLY216
A	TYR217
A	CYS219
A	ALA223
A	ALA231
A	ARG243
D	GLU89
D	ARG90

---

site_id	AC8
Number of Residues	1
Details	binding site for residue PO4 A 1008

Chain	Residue
A	ARG113

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN D 1001

Chain	Residue
D	CYS119
D	CYS122
D	HIS132
D	CYS139

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN D 1002

Chain	Residue
D	CYS133
D	CYS136
D	HIS146
D	CYS153

---

site_id	AD2
Number of Residues	6
Details	binding site for residue LMT D 1003

Chain	Residue
A	HIS142
A	TRP145
A	LMT1003
A	PLM1006
D	GLU30
D	HIS200

---

site_id	AD3
Number of Residues	14
Details	binding site for residue PLM D 1004

Chain	Residue
A	LMT1005
D	VAL19
D	PHE56
D	HIS145
D	SER147
D	TRP149
D	PHE162
D	PHE165
D	CYS173
D	ILE176
D	LEU204
D	VAL207
D	ALA208
D	LEU218

---

site_id	AD4
Number of Residues	4
Details	binding site for residue PO4 D 1005

Chain	Residue
D	LYS126
D	HIS131
D	HIS132
D	PO41006

---

site_id	AD5
Number of Residues	3
Details	binding site for residue PO4 D 1006

Chain	Residue
D	ARG117
D	HIS131
D	PO41005

---

site_id	AD6
Number of Residues	1
Details	binding site for residue LMT D 1007

Chain	Residue
D	PHE236

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	166
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	100
Details	Domain: {"description":"DHHC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00067","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"S-palmitoyl cysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00067","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BMS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q5W0Z9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	94
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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