6BMS
Palmitoyltransferase structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0014069 | cellular_component | postsynaptic density |
| A | 0016020 | cellular_component | membrane |
| A | 0016409 | molecular_function | palmitoyltransferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0018230 | biological_process | peptidyl-L-cysteine S-palmitoylation |
| A | 0019705 | molecular_function | protein-cysteine S-myristoyltransferase activity |
| A | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| A | 0045202 | cellular_component | synapse |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0072657 | biological_process | protein localization to membrane |
| A | 0140439 | molecular_function | protein-cysteine S-stearoyltransferase activity |
| A | 0140450 | biological_process | protein targeting to Golgi apparatus |
| D | 0000139 | cellular_component | Golgi membrane |
| D | 0005794 | cellular_component | Golgi apparatus |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0014069 | cellular_component | postsynaptic density |
| D | 0016020 | cellular_component | membrane |
| D | 0016409 | molecular_function | palmitoyltransferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0018230 | biological_process | peptidyl-L-cysteine S-palmitoylation |
| D | 0019705 | molecular_function | protein-cysteine S-myristoyltransferase activity |
| D | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| D | 0045202 | cellular_component | synapse |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0072657 | biological_process | protein localization to membrane |
| D | 0140439 | molecular_function | protein-cysteine S-stearoyltransferase activity |
| D | 0140450 | biological_process | protein targeting to Golgi apparatus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | CYS115 |
| A | CYS118 |
| A | HIS128 |
| A | CYS135 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | CYS129 |
| A | CYS132 |
| A | HIS142 |
| A | CYS149 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue LMT A 1003 |
| Chain | Residue |
| A | LEU229 |
| A | PHE232 |
| A | HOH1115 |
| D | ALA197 |
| D | HIS200 |
| D | LMT1003 |
| A | THR228 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue LMT A 1004 |
| Chain | Residue |
| A | PHE195 |
| A | HIS196 |
| D | THR232 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue LMT A 1005 |
| Chain | Residue |
| A | HIS196 |
| D | HIS145 |
| D | HIS146 |
| D | TRP149 |
| D | SER167 |
| D | PLM1004 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue PLM A 1006 |
| Chain | Residue |
| A | VAL18 |
| A | PHE55 |
| A | HIS141 |
| A | SER143 |
| A | TRP145 |
| A | PHE158 |
| A | PHE161 |
| A | VAL203 |
| A | PHE207 |
| A | LEU214 |
| A | HOH1108 |
| D | LMT1003 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue POV A 1007 |
| Chain | Residue |
| A | GLY216 |
| A | TYR217 |
| A | CYS219 |
| A | ALA223 |
| A | ALA231 |
| A | ARG243 |
| D | GLU89 |
| D | ARG90 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue PO4 A 1008 |
| Chain | Residue |
| A | ARG113 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1001 |
| Chain | Residue |
| D | CYS119 |
| D | CYS122 |
| D | HIS132 |
| D | CYS139 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1002 |
| Chain | Residue |
| D | CYS133 |
| D | CYS136 |
| D | HIS146 |
| D | CYS153 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue LMT D 1003 |
| Chain | Residue |
| A | HIS142 |
| A | TRP145 |
| A | LMT1003 |
| A | PLM1006 |
| D | GLU30 |
| D | HIS200 |
| site_id | AD3 |
| Number of Residues | 14 |
| Details | binding site for residue PLM D 1004 |
| Chain | Residue |
| A | LMT1005 |
| D | VAL19 |
| D | PHE56 |
| D | HIS145 |
| D | SER147 |
| D | TRP149 |
| D | PHE162 |
| D | PHE165 |
| D | CYS173 |
| D | ILE176 |
| D | LEU204 |
| D | VAL207 |
| D | ALA208 |
| D | LEU218 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 D 1005 |
| Chain | Residue |
| D | LYS126 |
| D | HIS131 |
| D | HIS132 |
| D | PO41006 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 D 1006 |
| Chain | Residue |
| D | ARG117 |
| D | HIS131 |
| D | PO41005 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue LMT D 1007 |
| Chain | Residue |
| D | PHE236 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 420 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | MET-6-PHE7 | |
| A | THR65-LYS156 | |
| A | CYS219-SER322 | |
| D | MET-5-PHE8 | |
| D | THR66-LYS160 | |
| D | CYS223-SER326 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 166 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | SER8-PHE28 | |
| A | TYR44-PHE64 | |
| A | PHE157-PHE177 | |
| A | PHE195-HIS218 | |
| D | SER9-PHE29 | |
| D | TYR45-PHE65 | |
| D | PHE161-PHE181 | |
| D | PHE199-HIS222 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 60 |
| Details | TOPO_DOM: Lumenal => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | GLU29-THR43 | |
| A | GLN178-LYS194 | |
| D | GLU30-THR44 | |
| D | GLN182-LYS198 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | ACT_SITE: S-palmitoyl cysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00067 |
| Chain | Residue | Details |
| A | SER143 | |
| D | SER147 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29326245, ECO:0007744|PDB:6BMS |
| Chain | Residue | Details |
| A | CYS115 | |
| D | CYS122 | |
| D | HIS132 | |
| D | CYS133 | |
| D | CYS136 | |
| D | CYS139 | |
| D | HIS146 | |
| D | CYS153 | |
| A | CYS118 | |
| A | HIS128 | |
| A | CYS129 | |
| A | CYS132 | |
| A | CYS135 | |
| A | HIS142 | |
| A | CYS149 | |
| D | CYS119 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q5W0Z9 |
| Chain | Residue | Details |
| A | LYS122 | |
| D | LYS126 |
