6BJO
PICK1 PDZ domain in complex with the small molecule inhibitor BIO124.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue DUY A 201 |
| Chain | Residue |
| A | LEU32 |
| A | HOH342 |
| A | ILE33 |
| A | GLY34 |
| A | ILE35 |
| A | SER36 |
| A | PHE53 |
| A | ALA87 |
| A | GLN91 |
| A | HOH323 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue DUY B 201 |
| Chain | Residue |
| B | LEU32 |
| B | ILE33 |
| B | GLY34 |
| B | ILE35 |
| B | PHE53 |
| B | LYS83 |
| B | GLN91 |
| B | HOH313 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS44 | |
| A | CYS46 | |
| B | CYS44 | |
| B | CYS46 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:20403402 |
| Chain | Residue | Details |
| A | THR82 | |
| B | THR82 |
