6BJE
Crystal Structure of Lysophospholipase A2 Conjugated with Phenylmethylsulfonyl Fluoride
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004622 | molecular_function | phosphatidylcholine lysophospholipase A1 activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005795 | cellular_component | Golgi stack |
| A | 0005829 | cellular_component | cytosol |
| A | 0007411 | biological_process | axon guidance |
| A | 0008474 | molecular_function | palmitoyl-(protein) hydrolase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0045296 | molecular_function | cadherin binding |
| A | 0046464 | biological_process | acylglycerol catabolic process |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0098734 | biological_process | macromolecule depalmitoylation |
| A | 1905344 | biological_process | prostaglandin catabolic process |
| B | 0004622 | molecular_function | phosphatidylcholine lysophospholipase A1 activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005795 | cellular_component | Golgi stack |
| B | 0005829 | cellular_component | cytosol |
| B | 0007411 | biological_process | axon guidance |
| B | 0008474 | molecular_function | palmitoyl-(protein) hydrolase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0045296 | molecular_function | cadherin binding |
| B | 0046464 | biological_process | acylglycerol catabolic process |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0098734 | biological_process | macromolecule depalmitoylation |
| B | 1905344 | biological_process | prostaglandin catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PMS A 301 |
| Chain | Residue |
| A | LEU33 |
| A | LEU78 |
| A | SER122 |
| A | GLN123 |
| A | TRP148 |
| A | MET178 |
| A | HIS210 |
| B | ASN67 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide PMS B 301 and SER B 122 |
| Chain | Residue |
| B | LEU66 |
| B | LEU78 |
| B | PHE121 |
| B | GLN123 |
| B | GLY124 |
| B | GLY125 |
| B | ALA126 |
| B | LEU145 |
| B | SER146 |
| B | CYS147 |
| B | TRP148 |
| B | MET178 |
| B | VAL179 |
| B | HIS210 |
| B | LEU33 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"28826475","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"O75608","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9QYL8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
