6B64
IMPase (AF2372) with 25 mM Asp
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006020 | biological_process | inositol metabolic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052832 | molecular_function | inositol monophosphate 3-phosphatase activity |
| A | 0052833 | molecular_function | inositol monophosphate 4-phosphatase activity |
| A | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
| B | 0006020 | biological_process | inositol metabolic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052832 | molecular_function | inositol monophosphate 3-phosphatase activity |
| B | 0052833 | molecular_function | inositol monophosphate 4-phosphatase activity |
| B | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue ASP A 501 |
| Chain | Residue |
| A | ARG11 |
| A | GLU125 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue ASP A 502 |
| Chain | Residue |
| A | MG506 |
| B | ASP302 |
| A | ASP85 |
| A | GLY170 |
| A | SER171 |
| A | ALA172 |
| A | ARG191 |
| A | ASP200 |
| A | SO4503 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | GLU67 |
| A | LEU84 |
| A | ASP85 |
| A | GLY86 |
| A | THR87 |
| A | ARG197 |
| A | ASP200 |
| A | ASP502 |
| A | SO4504 |
| A | MG505 |
| A | MG506 |
| B | ASP302 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | THR40 |
| A | PRO41 |
| A | ASP46 |
| A | GLU67 |
| A | GLU68 |
| A | THR87 |
| A | SO4503 |
| A | MG505 |
| A | MG507 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 505 |
| Chain | Residue |
| A | GLU67 |
| A | ASP82 |
| A | LEU84 |
| A | SO4503 |
| A | SO4504 |
| A | MG506 |
| A | HOH613 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 506 |
| Chain | Residue |
| A | ASP82 |
| A | ASP85 |
| A | ASP200 |
| A | ASP502 |
| A | SO4503 |
| A | MG505 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 507 |
| Chain | Residue |
| A | ASP38 |
| A | THR40 |
| A | PRO41 |
| A | GLU67 |
| A | GLU68 |
| A | SO4504 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue ASP A 508 |
| Chain | Residue |
| A | ASN151 |
| A | LYS164 |
| A | ARG165 |
| A | HOH622 |
| B | MET1 |
| B | LYS43 |
| B | ARG92 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue ASP A 509 |
| Chain | Residue |
| A | ARG165 |
| A | ARG167 |
| A | HOH601 |
| A | HOH611 |
| B | PHE88 |
| B | TYR156 |
| B | ARG191 |
| B | ASP304 |
| B | SO4305 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue ASP B 301 |
| Chain | Residue |
| A | MET1 |
| A | LYS43 |
| A | ARG92 |
| B | ASN151 |
| B | LYS164 |
| B | ARG165 |
| B | HOH403 |
| B | HOH425 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue ASP B 302 |
| Chain | Residue |
| A | PHE88 |
| A | TYR156 |
| A | ARG191 |
| A | ASP502 |
| A | SO4503 |
| A | HOH612 |
| B | ARG165 |
| B | ARG167 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue ASP B 303 |
| Chain | Residue |
| B | ARG11 |
| B | GLU125 |
| B | HOH415 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue ASP B 304 |
| Chain | Residue |
| A | ARG167 |
| A | ASP509 |
| B | ASP85 |
| B | TYR155 |
| B | GLY170 |
| B | ALA172 |
| B | ARG191 |
| B | LEU196 |
| B | ASP200 |
| B | SO4305 |
| site_id | AD5 |
| Number of Residues | 14 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | ASP82 |
| B | LEU84 |
| B | ASP85 |
| B | GLY86 |
| B | THR87 |
| B | ARG197 |
| B | ASP200 |
| B | ASP304 |
| B | SO4306 |
| B | MG309 |
| B | MG310 |
| A | ASP509 |
| A | HOH601 |
| B | GLU67 |
| site_id | AD6 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 B 306 |
| Chain | Residue |
| B | THR40 |
| B | PRO41 |
| B | ASP46 |
| B | GLU67 |
| B | GLU68 |
| B | THR87 |
| B | ARG197 |
| B | SO4305 |
| B | MG308 |
| B | MG309 |
| B | HOH410 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 307 |
| Chain | Residue |
| B | LYS110 |
| B | GLU209 |
| B | HOH402 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 308 |
| Chain | Residue |
| B | ASP38 |
| B | THR40 |
| B | PRO41 |
| B | GLU67 |
| B | GLU68 |
| B | SO4306 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue MG B 309 |
| Chain | Residue |
| B | GLU67 |
| B | ASP82 |
| B | LEU84 |
| B | ASP85 |
| B | SO4305 |
| B | SO4306 |
| B | MG310 |
| B | HOH410 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 310 |
| Chain | Residue |
| B | GLU67 |
| B | ASP82 |
| B | ASP85 |
| B | ARG197 |
| B | ASP200 |
| B | SO4305 |
| B | MG309 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP200 | |
| B | ASP38 | |
| B | THR40 | |
| B | GLU67 | |
| B | ASP82 | |
| B | LEU84 | |
| B | ASP85 | |
| B | ARG167 | |
| B | ALA172 | |
| B | ARG191 | |
| A | THR40 | |
| B | ASP200 | |
| A | GLU67 | |
| A | ASP82 | |
| A | LEU84 | |
| A | ASP85 | |
| A | ARG167 | |
| A | ALA172 | |
| A | ARG191 |
