6B3O

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0016020	cellular_component	membrane
A	0019031	cellular_component	viral envelope
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0039654	biological_process	fusion of virus membrane with host endosome membrane
A	0046813	biological_process	receptor-mediated virion attachment to host cell
A	0055036	cellular_component	virion membrane
A	0075509	biological_process	endocytosis involved in viral entry into host cell
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0016020	cellular_component	membrane
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0039654	biological_process	fusion of virus membrane with host endosome membrane
B	0046813	biological_process	receptor-mediated virion attachment to host cell
B	0055036	cellular_component	virion membrane
B	0075509	biological_process	endocytosis involved in viral entry into host cell
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
C	0016020	cellular_component	membrane
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0039654	biological_process	fusion of virus membrane with host endosome membrane
C	0046813	biological_process	receptor-mediated virion attachment to host cell
C	0055036	cellular_component	virion membrane
C	0075509	biological_process	endocytosis involved in viral entry into host cell

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	SITE: Cleavage; by host

Chain	Residue	Details
A	ALA717
B	ALA717
C	ALA717

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site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Cleavage => ECO:0000255|HAMAP-Rule:MF_04099

Chain	Residue	Details
A	ARG869
B	ARG869
C	ARG869

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site_id	SWS_FT_FI3
Number of Residues	24
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099

Chain	Residue	Details
A	ASN737
B	ASN754
B	ASN893
B	ASN1180
B	ASN1190
B	ASN1209
B	ASN1225
B	ASN1246
C	ASN737
C	ASN754
C	ASN893
A	ASN754
C	ASN1180
C	ASN1190
C	ASN1209
C	ASN1225
C	ASN1246
A	ASN893
A	ASN1180
A	ASN1190
A	ASN1209
A	ASN1225
A	ASN1246
B	ASN737

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