6B3L

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2,3-dihydro-1H-inden-2-amine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0016757	molecular_function	glycosyltransferase activity
A	0047975	molecular_function	guanosine phosphorylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue DMS A 301

Chain	Residue
A	PRO162
A	ASP163
A	CYS231
A	HIS232

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site_id	AC2
Number of Residues	4
Details	binding site for residue DMS A 302

Chain	Residue
A	ARG111
A	PRO285
A	HOH405
A	HOH426

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site_id	AC3
Number of Residues	7
Details	binding site for residue DMS A 303

Chain	Residue
A	GLN96
A	ALA99
A	ARG103
A	VAL148
A	VAL150
A	HOH447
A	ASN95

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site_id	AC4
Number of Residues	5
Details	binding site for residue DMS A 304

Chain	Residue
A	ILE53
A	ASN54
A	GLU182
A	ASN183
A	HOH461

---

site_id	AC5
Number of Residues	6
Details	binding site for residue DMS A 305

Chain	Residue
A	LEU118
A	PHE161
A	TYR202
A	MET221
A	HIS259
A	HOH502

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site_id	AC6
Number of Residues	6
Details	binding site for residue DMS A 306

Chain	Residue
A	VAL63
A	GLU91
A	GLY92
A	TYR93
A	PRO152
A	HOH561

---

site_id	AC7
Number of Residues	5
Details	binding site for residue XM0 A 307

Chain	Residue
A	ASN54
A	ASN183
A	MET275
A	TRP276
A	HOH513

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