6B33
Structure of RORgt in complex with a novel inverse agonist 3
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0004879 | molecular_function | nuclear receptor activity |
A | 0005634 | cellular_component | nucleus |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0003677 | molecular_function | DNA binding |
B | 0004879 | molecular_function | nuclear receptor activity |
B | 0005634 | cellular_component | nucleus |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue CF7 A 1000 |
Chain | Residue |
A | GLN286 |
A | PHE388 |
A | ILE400 |
A | HIS479 |
A | HOH1106 |
A | LEU287 |
A | CYS320 |
A | HIS323 |
A | LEU324 |
A | MET365 |
A | ALA368 |
A | PHE377 |
A | PHE378 |
site_id | AC2 |
Number of Residues | 11 |
Details | binding site for residue CF7 B 1000 |
Chain | Residue |
B | GLN286 |
B | CYS320 |
B | HIS323 |
B | LEU324 |
B | VAL361 |
B | MET365 |
B | ALA368 |
B | PHE377 |
B | ILE400 |
B | HIS479 |
B | HOH1109 |