6B30
Structure of RORgt in complex with a novel inverse agonist 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue CFG A 600 |
| Chain | Residue |
| A | GLN286 |
| A | LEU287 |
| A | CYS320 |
| A | HIS323 |
| A | MET365 |
| A | PHE377 |
| A | PHE378 |
| A | GLU379 |
| A | HOH706 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue CFG B 600 |
| Chain | Residue |
| B | GLN286 |
| B | LEU287 |
| B | HIS323 |
| B | ARG364 |
| B | MET365 |
| B | ALA368 |
| B | PHE377 |
| B | PHE378 |
| B | GLU379 |
| B | HOH702 |
