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6B2Z

Cryo-EM structure of the dimeric FO region of yeast mitochondrial ATP synthase

Functional Information from GO Data
ChainGOidnamespacecontents
00005515molecular_functionprotein binding
00005739cellular_componentmitochondrion
00005743cellular_componentmitochondrial inner membrane
00005758cellular_componentmitochondrial intermembrane space
00005829cellular_componentcytosol
00006811biological_processmonoatomic ion transport
00008289molecular_functionlipid binding
00015078molecular_functionproton transmembrane transporter activity
00015986biological_processproton motive force-driven ATP synthesis
00016887molecular_functionATP hydrolysis activity
00031966cellular_componentmitochondrial membrane
00033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
00042802molecular_functionidentical protein binding
00045259cellular_componentproton-transporting ATP synthase complex
00046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
01902600biological_processproton transmembrane transport
10005515molecular_functionprotein binding
10005739cellular_componentmitochondrion
10005743cellular_componentmitochondrial inner membrane
10005758cellular_componentmitochondrial intermembrane space
10005829cellular_componentcytosol
10006811biological_processmonoatomic ion transport
10008289molecular_functionlipid binding
10015078molecular_functionproton transmembrane transporter activity
10015986biological_processproton motive force-driven ATP synthesis
10016887molecular_functionATP hydrolysis activity
10031966cellular_componentmitochondrial membrane
10033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
10042802molecular_functionidentical protein binding
10045259cellular_componentproton-transporting ATP synthase complex
10046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
11902600biological_processproton transmembrane transport
20005515molecular_functionprotein binding
20005739cellular_componentmitochondrion
20005743cellular_componentmitochondrial inner membrane
20005758cellular_componentmitochondrial intermembrane space
20005829cellular_componentcytosol
20006811biological_processmonoatomic ion transport
20008289molecular_functionlipid binding
20015078molecular_functionproton transmembrane transporter activity
20015986biological_processproton motive force-driven ATP synthesis
20016887molecular_functionATP hydrolysis activity
20031966cellular_componentmitochondrial membrane
20033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
20042802molecular_functionidentical protein binding
20045259cellular_componentproton-transporting ATP synthase complex
20046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
21902600biological_processproton transmembrane transport
30005515molecular_functionprotein binding
30005739cellular_componentmitochondrion
30005743cellular_componentmitochondrial inner membrane
30005758cellular_componentmitochondrial intermembrane space
30005829cellular_componentcytosol
30006811biological_processmonoatomic ion transport
30008289molecular_functionlipid binding
30015078molecular_functionproton transmembrane transporter activity
30015986biological_processproton motive force-driven ATP synthesis
30016887molecular_functionATP hydrolysis activity
30031966cellular_componentmitochondrial membrane
30033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
30042802molecular_functionidentical protein binding
30045259cellular_componentproton-transporting ATP synthase complex
30046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
31902600biological_processproton transmembrane transport
40005515molecular_functionprotein binding
40005739cellular_componentmitochondrion
40005743cellular_componentmitochondrial inner membrane
40005758cellular_componentmitochondrial intermembrane space
40005829cellular_componentcytosol
40006811biological_processmonoatomic ion transport
40008289molecular_functionlipid binding
40015078molecular_functionproton transmembrane transporter activity
40015986biological_processproton motive force-driven ATP synthesis
40016887molecular_functionATP hydrolysis activity
40031966cellular_componentmitochondrial membrane
40033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
40042802molecular_functionidentical protein binding
40045259cellular_componentproton-transporting ATP synthase complex
40046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
41902600biological_processproton transmembrane transport
50005515molecular_functionprotein binding
50005739cellular_componentmitochondrion
50005743cellular_componentmitochondrial inner membrane
50005758cellular_componentmitochondrial intermembrane space
50005829cellular_componentcytosol
50006811biological_processmonoatomic ion transport
50008289molecular_functionlipid binding
50015078molecular_functionproton transmembrane transporter activity
50015986biological_processproton motive force-driven ATP synthesis
50016887molecular_functionATP hydrolysis activity
50031966cellular_componentmitochondrial membrane
50033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
50042802molecular_functionidentical protein binding
50045259cellular_componentproton-transporting ATP synthase complex
50046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
51902600biological_processproton transmembrane transport
60005515molecular_functionprotein binding
60005739cellular_componentmitochondrion
60005743cellular_componentmitochondrial inner membrane
60005758cellular_componentmitochondrial intermembrane space
60005829cellular_componentcytosol
60006811biological_processmonoatomic ion transport
60008289molecular_functionlipid binding
60015078molecular_functionproton transmembrane transporter activity
60015986biological_processproton motive force-driven ATP synthesis
60016887molecular_functionATP hydrolysis activity
60031966cellular_componentmitochondrial membrane
60033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
60042802molecular_functionidentical protein binding
60045259cellular_componentproton-transporting ATP synthase complex
60046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
61902600biological_processproton transmembrane transport
70005515molecular_functionprotein binding
70005739cellular_componentmitochondrion
70005743cellular_componentmitochondrial inner membrane
70005758cellular_componentmitochondrial intermembrane space
70005829cellular_componentcytosol
70006811biological_processmonoatomic ion transport
70008289molecular_functionlipid binding
70015078molecular_functionproton transmembrane transporter activity
70015986biological_processproton motive force-driven ATP synthesis
70016887molecular_functionATP hydrolysis activity
70031966cellular_componentmitochondrial membrane
70033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
70042802molecular_functionidentical protein binding
70045259cellular_componentproton-transporting ATP synthase complex
70046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
71902600biological_processproton transmembrane transport
80005515molecular_functionprotein binding
80005739cellular_componentmitochondrion
80005743cellular_componentmitochondrial inner membrane
80005758cellular_componentmitochondrial intermembrane space
80005829cellular_componentcytosol
80006811biological_processmonoatomic ion transport
80008289molecular_functionlipid binding
80015078molecular_functionproton transmembrane transporter activity
80015986biological_processproton motive force-driven ATP synthesis
80016887molecular_functionATP hydrolysis activity
80031966cellular_componentmitochondrial membrane
80033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
80042802molecular_functionidentical protein binding
80045259cellular_componentproton-transporting ATP synthase complex
80046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
81902600biological_processproton transmembrane transport
90005515molecular_functionprotein binding
90005739cellular_componentmitochondrion
90005743cellular_componentmitochondrial inner membrane
90005758cellular_componentmitochondrial intermembrane space
90005829cellular_componentcytosol
90006811biological_processmonoatomic ion transport
90008289molecular_functionlipid binding
90015078molecular_functionproton transmembrane transporter activity
90015986biological_processproton motive force-driven ATP synthesis
90016887molecular_functionATP hydrolysis activity
90031966cellular_componentmitochondrial membrane
90033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
90042802molecular_functionidentical protein binding
90045259cellular_componentproton-transporting ATP synthase complex
90046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
91902600biological_processproton transmembrane transport
A0005739cellular_componentmitochondrion
A0005743cellular_componentmitochondrial inner membrane
A0006754biological_processATP biosynthetic process
A0006811biological_processmonoatomic ion transport
A0015078molecular_functionproton transmembrane transporter activity
A0015986biological_processproton motive force-driven ATP synthesis
A0031966cellular_componentmitochondrial membrane
A0045259cellular_componentproton-transporting ATP synthase complex
A0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
A1902600biological_processproton transmembrane transport
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005743cellular_componentmitochondrial inner membrane
B0005758cellular_componentmitochondrial intermembrane space
B0005829cellular_componentcytosol
B0006811biological_processmonoatomic ion transport
B0008289molecular_functionlipid binding
B0015078molecular_functionproton transmembrane transporter activity
B0015986biological_processproton motive force-driven ATP synthesis
B0016887molecular_functionATP hydrolysis activity
B0031966cellular_componentmitochondrial membrane
B0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
B0042802molecular_functionidentical protein binding
B0045259cellular_componentproton-transporting ATP synthase complex
B0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
B1902600biological_processproton transmembrane transport
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005743cellular_componentmitochondrial inner membrane
C0005758cellular_componentmitochondrial intermembrane space
C0005829cellular_componentcytosol
C0006811biological_processmonoatomic ion transport
C0008289molecular_functionlipid binding
C0015078molecular_functionproton transmembrane transporter activity
C0015986biological_processproton motive force-driven ATP synthesis
C0016887molecular_functionATP hydrolysis activity
C0031966cellular_componentmitochondrial membrane
C0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
C0042802molecular_functionidentical protein binding
C0045259cellular_componentproton-transporting ATP synthase complex
C0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
C1902600biological_processproton transmembrane transport
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005743cellular_componentmitochondrial inner membrane
D0005758cellular_componentmitochondrial intermembrane space
D0005829cellular_componentcytosol
D0006811biological_processmonoatomic ion transport
D0008289molecular_functionlipid binding
D0015078molecular_functionproton transmembrane transporter activity
D0015986biological_processproton motive force-driven ATP synthesis
D0016887molecular_functionATP hydrolysis activity
D0031966cellular_componentmitochondrial membrane
D0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
D0042802molecular_functionidentical protein binding
D0045259cellular_componentproton-transporting ATP synthase complex
D0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
D1902600biological_processproton transmembrane transport
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005743cellular_componentmitochondrial inner membrane
E0005758cellular_componentmitochondrial intermembrane space
E0005829cellular_componentcytosol
E0006811biological_processmonoatomic ion transport
E0008289molecular_functionlipid binding
E0015078molecular_functionproton transmembrane transporter activity
E0015986biological_processproton motive force-driven ATP synthesis
E0016887molecular_functionATP hydrolysis activity
E0031966cellular_componentmitochondrial membrane
E0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
E0042802molecular_functionidentical protein binding
E0045259cellular_componentproton-transporting ATP synthase complex
E0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
E1902600biological_processproton transmembrane transport
F0005515molecular_functionprotein binding
F0005739cellular_componentmitochondrion
F0005743cellular_componentmitochondrial inner membrane
F0005758cellular_componentmitochondrial intermembrane space
F0005829cellular_componentcytosol
F0006811biological_processmonoatomic ion transport
F0008289molecular_functionlipid binding
F0015078molecular_functionproton transmembrane transporter activity
F0015986biological_processproton motive force-driven ATP synthesis
F0016887molecular_functionATP hydrolysis activity
F0031966cellular_componentmitochondrial membrane
F0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
F0042802molecular_functionidentical protein binding
F0045259cellular_componentproton-transporting ATP synthase complex
F0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
F1902600biological_processproton transmembrane transport
G0005515molecular_functionprotein binding
G0005739cellular_componentmitochondrion
G0005743cellular_componentmitochondrial inner membrane
G0005758cellular_componentmitochondrial intermembrane space
G0005829cellular_componentcytosol
G0006811biological_processmonoatomic ion transport
G0008289molecular_functionlipid binding
G0015078molecular_functionproton transmembrane transporter activity
G0015986biological_processproton motive force-driven ATP synthesis
G0016887molecular_functionATP hydrolysis activity
G0031966cellular_componentmitochondrial membrane
G0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
G0042802molecular_functionidentical protein binding
G0045259cellular_componentproton-transporting ATP synthase complex
G0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
G1902600biological_processproton transmembrane transport
H0005515molecular_functionprotein binding
H0005739cellular_componentmitochondrion
H0005743cellular_componentmitochondrial inner membrane
H0005758cellular_componentmitochondrial intermembrane space
H0005829cellular_componentcytosol
H0006811biological_processmonoatomic ion transport
H0008289molecular_functionlipid binding
H0015078molecular_functionproton transmembrane transporter activity
H0015986biological_processproton motive force-driven ATP synthesis
H0016887molecular_functionATP hydrolysis activity
H0031966cellular_componentmitochondrial membrane
H0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
H0042802molecular_functionidentical protein binding
H0045259cellular_componentproton-transporting ATP synthase complex
H0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
H1902600biological_processproton transmembrane transport
I0005515molecular_functionprotein binding
I0005739cellular_componentmitochondrion
I0005743cellular_componentmitochondrial inner membrane
I0005758cellular_componentmitochondrial intermembrane space
I0005829cellular_componentcytosol
I0006811biological_processmonoatomic ion transport
I0008289molecular_functionlipid binding
I0015078molecular_functionproton transmembrane transporter activity
I0015986biological_processproton motive force-driven ATP synthesis
I0016887molecular_functionATP hydrolysis activity
I0031966cellular_componentmitochondrial membrane
I0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
I0042802molecular_functionidentical protein binding
I0045259cellular_componentproton-transporting ATP synthase complex
I0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
I1902600biological_processproton transmembrane transport
J0005515molecular_functionprotein binding
J0005739cellular_componentmitochondrion
J0005743cellular_componentmitochondrial inner membrane
J0005758cellular_componentmitochondrial intermembrane space
J0005829cellular_componentcytosol
J0006811biological_processmonoatomic ion transport
J0008289molecular_functionlipid binding
J0015078molecular_functionproton transmembrane transporter activity
J0015986biological_processproton motive force-driven ATP synthesis
J0016887molecular_functionATP hydrolysis activity
J0031966cellular_componentmitochondrial membrane
J0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
J0042802molecular_functionidentical protein binding
J0045259cellular_componentproton-transporting ATP synthase complex
J0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
J1902600biological_processproton transmembrane transport
K0005515molecular_functionprotein binding
K0005739cellular_componentmitochondrion
K0005743cellular_componentmitochondrial inner membrane
K0005758cellular_componentmitochondrial intermembrane space
K0005829cellular_componentcytosol
K0006811biological_processmonoatomic ion transport
K0008289molecular_functionlipid binding
K0015078molecular_functionproton transmembrane transporter activity
K0015986biological_processproton motive force-driven ATP synthesis
K0016887molecular_functionATP hydrolysis activity
K0031966cellular_componentmitochondrial membrane
K0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
K0042802molecular_functionidentical protein binding
K0045259cellular_componentproton-transporting ATP synthase complex
K0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
K1902600biological_processproton transmembrane transport
L0005739cellular_componentmitochondrion
L0005743cellular_componentmitochondrial inner membrane
L0006754biological_processATP biosynthetic process
L0006811biological_processmonoatomic ion transport
L0015078molecular_functionproton transmembrane transporter activity
L0015986biological_processproton motive force-driven ATP synthesis
L0031966cellular_componentmitochondrial membrane
L0045259cellular_componentproton-transporting ATP synthase complex
L0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
L1902600biological_processproton transmembrane transport
M0005739cellular_componentmitochondrion
M0005743cellular_componentmitochondrial inner membrane
M0006754biological_processATP biosynthetic process
M0006811biological_processmonoatomic ion transport
M0015078molecular_functionproton transmembrane transporter activity
M0015986biological_processproton motive force-driven ATP synthesis
M0045259cellular_componentproton-transporting ATP synthase complex
M0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
M1902600biological_processproton transmembrane transport
N0015078molecular_functionproton transmembrane transporter activity
N0015986biological_processproton motive force-driven ATP synthesis
O0005739cellular_componentmitochondrion
O0005743cellular_componentmitochondrial inner membrane
O0006754biological_processATP biosynthetic process
O0006811biological_processmonoatomic ion transport
O0015078molecular_functionproton transmembrane transporter activity
O0015986biological_processproton motive force-driven ATP synthesis
O0045259cellular_componentproton-transporting ATP synthase complex
O0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
O1902600biological_processproton transmembrane transport
Q0005739cellular_componentmitochondrion
Q0005743cellular_componentmitochondrial inner membrane
Q0006754biological_processATP biosynthetic process
Q0006811biological_processmonoatomic ion transport
Q0015986biological_processproton motive force-driven ATP synthesis
Q0016887molecular_functionATP hydrolysis activity
Q0045259cellular_componentproton-transporting ATP synthase complex
Q0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
Q1902600biological_processproton transmembrane transport
S0005739cellular_componentmitochondrion
S0005743cellular_componentmitochondrial inner membrane
S0006754biological_processATP biosynthetic process
S0006811biological_processmonoatomic ion transport
S0015078molecular_functionproton transmembrane transporter activity
S0015986biological_processproton motive force-driven ATP synthesis
S0031966cellular_componentmitochondrial membrane
S0033615biological_processmitochondrial proton-transporting ATP synthase complex assembly
S0045259cellular_componentproton-transporting ATP synthase complex
S0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
S0065003biological_processprotein-containing complex assembly
S1902600biological_processproton transmembrane transport
T0005739cellular_componentmitochondrion
T0005743cellular_componentmitochondrial inner membrane
T0006754biological_processATP biosynthetic process
T0006811biological_processmonoatomic ion transport
T0015986biological_processproton motive force-driven ATP synthesis
T0045259cellular_componentproton-transporting ATP synthase complex
T0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
T0065003biological_processprotein-containing complex assembly
T1902600biological_processproton transmembrane transport
a0005739cellular_componentmitochondrion
a0005743cellular_componentmitochondrial inner membrane
a0006754biological_processATP biosynthetic process
a0006811biological_processmonoatomic ion transport
a0015078molecular_functionproton transmembrane transporter activity
a0015986biological_processproton motive force-driven ATP synthesis
a0045259cellular_componentproton-transporting ATP synthase complex
a0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
a1902600biological_processproton transmembrane transport
b0015078molecular_functionproton transmembrane transporter activity
b0015986biological_processproton motive force-driven ATP synthesis
d0005739cellular_componentmitochondrion
d0005743cellular_componentmitochondrial inner membrane
d0006754biological_processATP biosynthetic process
d0006811biological_processmonoatomic ion transport
d0015078molecular_functionproton transmembrane transporter activity
d0015986biological_processproton motive force-driven ATP synthesis
d0045259cellular_componentproton-transporting ATP synthase complex
d0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
d1902600biological_processproton transmembrane transport
f0005739cellular_componentmitochondrion
f0005743cellular_componentmitochondrial inner membrane
f0006754biological_processATP biosynthetic process
f0006811biological_processmonoatomic ion transport
f0015986biological_processproton motive force-driven ATP synthesis
f0016887molecular_functionATP hydrolysis activity
f0045259cellular_componentproton-transporting ATP synthase complex
f0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
f1902600biological_processproton transmembrane transport
i0005739cellular_componentmitochondrion
i0005743cellular_componentmitochondrial inner membrane
i0006754biological_processATP biosynthetic process
i0006811biological_processmonoatomic ion transport
i0015078molecular_functionproton transmembrane transporter activity
i0015986biological_processproton motive force-driven ATP synthesis
i0031966cellular_componentmitochondrial membrane
i0033615biological_processmitochondrial proton-transporting ATP synthase complex assembly
i0045259cellular_componentproton-transporting ATP synthase complex
i0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
i0065003biological_processprotein-containing complex assembly
i1902600biological_processproton transmembrane transport
k0005739cellular_componentmitochondrion
k0005743cellular_componentmitochondrial inner membrane
k0006754biological_processATP biosynthetic process
k0006811biological_processmonoatomic ion transport
k0015986biological_processproton motive force-driven ATP synthesis
k0045259cellular_componentproton-transporting ATP synthase complex
k0046933molecular_functionproton-transporting ATP synthase activity, rotational mechanism
k0065003biological_processprotein-containing complex assembly
k1902600biological_processproton transmembrane transport
Functional Information from PROSITE/UniProt
site_idPS00449
Number of Residues10
DetailsATPASE_A ATP synthase a subunit signature. SLGLRLGSNI
ChainResidueDetails
MSER172-ILE181

site_idPS00605
Number of Residues22
DetailsATPASE_C ATP synthase c subunit signature. SRNPsikdtVfPmaILgfaLsE
ChainResidueDetails
1SER38-GLU59

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1110
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues20
DetailsSite: {"description":"Reversibly protonated during proton transport","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues14
DetailsModified residue: {"description":"N-formylmethionine","evidences":[{"source":"PubMed","id":"2894987","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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