Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
B | 0008800 | molecular_function | beta-lactamase activity |
B | 0017001 | biological_process | antibiotic catabolic process |
B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue C8V A 301 |
Chain | Residue |
A | CYS69 |
A | GLY236 |
A | THR237 |
A | CYS238 |
A | HOH403 |
A | HOH411 |
A | HOH427 |
A | HOH435 |
A | HOH537 |
A | SER70 |
A | TRP105 |
A | SER130 |
A | ASN132 |
A | ASN170 |
A | THR216 |
A | LYS234 |
A | THR235 |
site_id | AC2 |
Number of Residues | 15 |
Details | binding site for residue CIT A 302 |
Chain | Residue |
A | TYR97 |
A | GLY98 |
A | LYS99 |
A | ASN100 |
A | ALA101 |
A | HOH437 |
A | HOH446 |
A | HOH453 |
A | HOH483 |
A | HOH571 |
B | ARG96 |
B | ARG164 |
B | ARG178 |
B | EDO303 |
B | HOH466 |
site_id | AC3 |
Number of Residues | 10 |
Details | binding site for residue CIT A 303 |
Chain | Residue |
A | PRO94 |
A | ARG96 |
A | THR115 |
A | ARG178 |
A | EDO308 |
A | HOH455 |
A | HOH501 |
B | ASN100 |
B | ALA101 |
B | LYS140 |
site_id | AC4 |
Number of Residues | 13 |
Details | binding site for residue CIT A 304 |
Chain | Residue |
A | TRP105 |
A | GLN191 |
A | GLY196 |
A | SER197 |
A | THR237 |
A | GLY239 |
A | HIS274 |
A | HOH401 |
A | HOH403 |
A | HOH419 |
A | HOH424 |
A | HOH480 |
A | HOH537 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue EDO A 305 |
Chain | Residue |
A | ALA124 |
A | ALA125 |
A | GLN128 |
A | TYR129 |
A | PRO174 |
A | HOH521 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue EDO A 306 |
Chain | Residue |
A | ALA82 |
A | GLN85 |
A | GLN86 |
A | VAL103 |
A | PRO104 |
A | HOH443 |
A | HOH447 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue EDO A 307 |
Chain | Residue |
A | GLU110 |
A | PRO202 |
A | GLN203 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue EDO A 308 |
Chain | Residue |
A | ARG96 |
A | THR115 |
A | CIT303 |
B | ASN136 |
B | TRP165 |
B | HOH467 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue EDO A 309 |
Chain | Residue |
A | GLN205 |
A | VAL208 |
A | LYS212 |
A | HOH520 |
site_id | AD1 |
Number of Residues | 3 |
Details | binding site for residue EDO A 310 |
Chain | Residue |
A | PRO107 |
A | ARG204 |
A | HOH402 |
site_id | AD2 |
Number of Residues | 7 |
Details | binding site for residue EDO B 302 |
Chain | Residue |
B | ALA124 |
B | ALA125 |
B | GLN128 |
B | TYR129 |
B | ILE173 |
B | PRO174 |
B | HOH452 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for residue EDO B 303 |
Chain | Residue |
A | CIT302 |
A | HOH437 |
B | PRO94 |
B | THR115 |
B | ARG178 |
B | EDO305 |
site_id | AD4 |
Number of Residues | 5 |
Details | binding site for residue EDO B 304 |
Chain | Residue |
B | LYS212 |
B | TRP251 |
B | HOH438 |
B | GLN205 |
B | VAL208 |
site_id | AD5 |
Number of Residues | 8 |
Details | binding site for residue EDO B 305 |
Chain | Residue |
B | TYR112 |
B | THR115 |
B | GLY116 |
B | GLU121 |
B | ILE173 |
B | ARG178 |
B | EDO303 |
B | HOH479 |
site_id | AD6 |
Number of Residues | 19 |
Details | binding site for Di-peptide C8V B 301 and SER B 70 |
Chain | Residue |
B | LEU68 |
B | CYS69 |
B | SER71 |
B | PHE72 |
B | LYS73 |
B | TRP105 |
B | SER130 |
B | ASN132 |
B | LEU167 |
B | ASN170 |
B | THR216 |
B | LYS234 |
B | THR235 |
B | GLY236 |
B | THR237 |
B | CYS238 |
B | HOH408 |
B | HOH513 |
B | HOH546 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Acyl-ester intermediate => ECO:0000250 |
Chain | Residue | Details |
A | SER70 | |
B | SER70 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000250 |
Chain | Residue | Details |
A | GLU168 | |
B | GLU168 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | LYS234 | |
B | LYS234 | |