6AYM
Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| A | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009164 | biological_process | nucleoside catabolic process |
| A | 0009234 | biological_process | menaquinone biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| A | 0102246 | molecular_function | 6-amino-6-deoxyfutalosine hydrolase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| B | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009164 | biological_process | nucleoside catabolic process |
| B | 0009234 | biological_process | menaquinone biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0102246 | molecular_function | 6-amino-6-deoxyfutalosine hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | SER10 |
| A | THR14 |
| A | TYR34 |
| A | HOH477 |
| A | HOH586 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ILE119 |
| A | LEU179 |
| A | EDO304 |
| A | HOH441 |
| A | HOH463 |
| A | LEU95 |
| A | GLN97 |
| A | GLU116 |
| A | ILE117 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | ASN30 |
| A | LYS49 |
| A | ASN54 |
| A | HOH457 |
| B | ASN115 |
| B | LEU179 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ASN115 |
| A | GLU116 |
| A | EDO302 |
| A | HOH405 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | MET1 |
| A | VAL70 |
| A | ASP122 |
| A | LYS124 |
| A | LEU125 |
| A | PRO187 |
| A | HOH417 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | PRO15 |
| A | GLU18 |
| A | THR19 |
| A | LYS215 |
| A | HOH467 |
| A | HOH531 |
| A | HOH592 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| A | ASN115 |
| A | LEU179 |
| B | ALA29 |
| B | ASN30 |
| B | LYS49 |
| B | ASN54 |
| B | HOH510 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | GLN97 |
| B | GLU116 |
| B | ILE117 |
| B | ILE119 |
| B | LEU179 |
| B | HOH413 |
| B | HOH438 |
| B | HOH502 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | LYS157 |
| B | LYS160 |
| B | ILE161 |
| B | HOH416 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
