Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006699 | biological_process | bile acid biosynthetic process |
| A | 0008387 | molecular_function | steroid 7-alpha-hydroxylase activity |
| A | 0008396 | molecular_function | oxysterol 7-alpha-hydroxylase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0042632 | biological_process | cholesterol homeostasis |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue VOR A 501 |
| Chain | Residue |
| A | TYR107 |
| A | HEM502 |
| A | PHE114 |
| A | TYR120 |
| A | ALA289 |
| A | PHE292 |
| A | ALA293 |
| A | THR297 |
| A | LEU358 |
| A | MET360 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue HEM A 502 |
| Chain | Residue |
| A | TYR107 |
| A | TYR120 |
| A | ALA293 |
| A | GLY294 |
| A | THR297 |
| A | SER298 |
| A | LEU358 |
| A | ILE361 |
| A | ARG363 |
| A | PRO422 |
| A | PHE423 |
| A | GLY424 |
| A | HIS428 |
| A | LYS429 |
| A | CYS430 |
| A | ILE431 |
| A | GLY432 |
| A | ALA436 |
| A | VOR501 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGRHKCIG |
| Chain | Residue | Details |
| A | PHE423-GLY432 | |
