6AXV
Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016032 | biological_process | viral process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue IOD A 301 |
| Chain | Residue |
| A | ALA92 |
| A | PRO157 |
| A | LYS158 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 302 |
| Chain | Residue |
| A | LYS170 |
| A | ARG173 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 303 |
| Chain | Residue |
| A | GLN219 |
| A | CL310 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 304 |
| Chain | Residue |
| A | GLN179 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 306 |
| Chain | Residue |
| A | 1B0315 |
| A | ASN57 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 307 |
| Chain | Residue |
| A | PRO17 |
| A | ARG18 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 308 |
| Chain | Residue |
| A | ARG18 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 309 |
| Chain | Residue |
| A | CL312 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 310 |
| Chain | Residue |
| A | PHE161 |
| A | ARG162 |
| A | CYS218 |
| A | GLN219 |
| A | IOD303 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 311 |
| Chain | Residue |
| A | ALA177 |
| A | SER178 |
| A | HOH407 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 312 |
| Chain | Residue |
| A | CL309 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 313 |
| Chain | Residue |
| A | ARG167 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 314 |
| Chain | Residue |
| A | ALA31 |
| A | PHE32 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for residue 1B0 A 315 |
| Chain | Residue |
| A | ASN53 |
| A | LEU56 |
| A | ASN57 |
| A | GLN63 |
| A | MET66 |
| A | LYS70 |
| A | ALA105 |
| A | ILE107 |
| A | TYR130 |
| A | TYR169 |
| A | ARG173 |
| A | LYS182 |
| A | CL306 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | Region: {"description":"Interaction with human PPIA/CYPA and NUP153","evidences":[{"source":"PubMed","id":"24130490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8980234","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Region: {"description":"PPIA/CYPA-binding loop","evidences":[{"source":"UniProtKB","id":"P04591","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by host MAPK1","evidences":[{"source":"PubMed","id":"24509437","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
