Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6AWC

Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
01	0003677	molecular_function	DNA binding
01	0003899	molecular_function	DNA-directed RNA polymerase activity
01	0006351	biological_process	DNA-templated transcription
01	0046983	molecular_function	protein dimerization activity
02	0003677	molecular_function	DNA binding
02	0003899	molecular_function	DNA-directed RNA polymerase activity
02	0006351	biological_process	DNA-templated transcription
02	0046983	molecular_function	protein dimerization activity
03	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
03	0000428	cellular_component	DNA-directed RNA polymerase complex
03	0003677	molecular_function	DNA binding
03	0003899	molecular_function	DNA-directed RNA polymerase activity
03	0005515	molecular_function	protein binding
03	0005737	cellular_component	cytoplasm
03	0005829	cellular_component	cytosol
03	0006351	biological_process	DNA-templated transcription
03	0006352	biological_process	DNA-templated transcription initiation
03	0006879	biological_process	intracellular iron ion homeostasis
03	0008023	cellular_component	transcription elongation factor complex
03	0009408	biological_process	response to heat
03	0016020	cellular_component	membrane
03	0016740	molecular_function	transferase activity
03	0016779	molecular_function	nucleotidyltransferase activity
03	0031564	biological_process	transcription antitermination
03	0032549	molecular_function	ribonucleoside binding
03	0032784	biological_process	regulation of DNA-templated transcription elongation
03	0034062	molecular_function	5'-3' RNA polymerase activity
03	0036460	biological_process	cellular response to cell envelope stress
03	0042128	biological_process	nitrate assimilation
03	0044780	biological_process	bacterial-type flagellum assembly
03	0046677	biological_process	response to antibiotic
03	0048870	biological_process	cell motility
03	0071973	biological_process	bacterial-type flagellum-dependent cell motility
03	0090605	biological_process	submerged biofilm formation
03	2000142	biological_process	regulation of DNA-templated transcription initiation
04	0000287	molecular_function	magnesium ion binding
04	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
04	0000428	cellular_component	DNA-directed RNA polymerase complex
04	0003677	molecular_function	DNA binding
04	0003899	molecular_function	DNA-directed RNA polymerase activity
04	0005515	molecular_function	protein binding
04	0005737	cellular_component	cytoplasm
04	0005829	cellular_component	cytosol
04	0006351	biological_process	DNA-templated transcription
04	0006352	biological_process	DNA-templated transcription initiation
04	0006879	biological_process	intracellular iron ion homeostasis
04	0008023	cellular_component	transcription elongation factor complex
04	0008270	molecular_function	zinc ion binding
04	0009408	biological_process	response to heat
04	0016020	cellular_component	membrane
04	0016740	molecular_function	transferase activity
04	0016779	molecular_function	nucleotidyltransferase activity
04	0031564	biological_process	transcription antitermination
04	0032784	biological_process	regulation of DNA-templated transcription elongation
04	0034062	molecular_function	5'-3' RNA polymerase activity
04	0036460	biological_process	cellular response to cell envelope stress
04	0042128	biological_process	nitrate assimilation
04	0044780	biological_process	bacterial-type flagellum assembly
04	0046677	biological_process	response to antibiotic
04	0046872	molecular_function	metal ion binding
04	0048870	biological_process	cell motility
04	0071973	biological_process	bacterial-type flagellum-dependent cell motility
04	0090605	biological_process	submerged biofilm formation
04	2000142	biological_process	regulation of DNA-templated transcription initiation
05	0003677	molecular_function	DNA binding
05	0003899	molecular_function	DNA-directed RNA polymerase activity
05	0006351	biological_process	DNA-templated transcription
E	0000028	biological_process	ribosomal small subunit assembly
E	0002181	biological_process	cytoplasmic translation
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0008270	molecular_function	zinc ion binding
E	0015935	cellular_component	small ribosomal subunit
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0006412	biological_process	translation
G	0000028	biological_process	ribosomal small subunit assembly
G	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0006353	biological_process	DNA-templated transcription termination
G	0006412	biological_process	translation
G	0006417	biological_process	regulation of translation
G	0015935	cellular_component	small ribosomal subunit
G	0019843	molecular_function	rRNA binding
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	0031564	biological_process	transcription antitermination
G	0042254	biological_process	ribosome biogenesis
G	0042274	biological_process	ribosomal small subunit biogenesis
G	0045947	biological_process	negative regulation of translational initiation
G	0046677	biological_process	response to antibiotic
G	0048027	molecular_function	mRNA 5'-UTR binding
G	1990145	biological_process	maintenance of translational fidelity
G	1990904	cellular_component	ribonucleoprotein complex
H	0000028	biological_process	ribosomal small subunit assembly
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015935	cellular_component	small ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0042254	biological_process	ribosome biogenesis
H	0046677	biological_process	response to antibiotic
H	1990145	biological_process	maintenance of translational fidelity
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
K	0000028	biological_process	ribosomal small subunit assembly
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0006417	biological_process	regulation of translation
K	0019843	molecular_function	rRNA binding
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0043488	biological_process	regulation of mRNA stability
K	1990904	cellular_component	ribonucleoprotein complex
L	0000049	molecular_function	tRNA binding
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0000049	molecular_function	tRNA binding
M	0001072	molecular_function	transcription antitermination factor activity, RNA binding
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0008023	cellular_component	transcription elongation factor complex
M	0015935	cellular_component	small ribosomal subunit
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0031564	biological_process	transcription antitermination
M	0032784	biological_process	regulation of DNA-templated transcription elongation
M	0042254	biological_process	ribosome biogenesis
M	1990904	cellular_component	ribonucleoprotein complex
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0019843	molecular_function	rRNA binding
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0070181	molecular_function	small ribosomal subunit rRNA binding
N	1990904	cellular_component	ribonucleoprotein complex
O	0000049	molecular_function	tRNA binding
O	0000372	biological_process	Group I intron splicing
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015935	cellular_component	small ribosomal subunit
O	0019843	molecular_function	rRNA binding
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0033120	biological_process	positive regulation of RNA splicing
O	0034336	molecular_function	misfolded RNA binding
O	0034337	biological_process	RNA folding
O	0046677	biological_process	response to antibiotic
O	1990145	biological_process	maintenance of translational fidelity
O	1990904	cellular_component	ribonucleoprotein complex
P	0000049	molecular_function	tRNA binding
P	0002181	biological_process	cytoplasmic translation
P	0003676	molecular_function	nucleic acid binding
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0019843	molecular_function	rRNA binding
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000028	biological_process	ribosomal small subunit assembly
Q	0000049	molecular_function	tRNA binding
Q	0002181	biological_process	cytoplasmic translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0000028	biological_process	ribosomal small subunit assembly
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0006417	biological_process	regulation of translation
R	0019843	molecular_function	rRNA binding
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0070181	molecular_function	small ribosomal subunit rRNA binding
R	1990904	cellular_component	ribonucleoprotein complex
S	0000028	biological_process	ribosomal small subunit assembly
S	0000400	molecular_function	four-way junction DNA binding
S	0002181	biological_process	cytoplasmic translation
S	0003735	molecular_function	structural constituent of ribosome
S	0004518	molecular_function	nuclease activity
S	0004519	molecular_function	endonuclease activity
S	0004520	molecular_function	DNA endonuclease activity
S	0005737	cellular_component	cytoplasm
S	0005840	cellular_component	ribosome
S	0006259	biological_process	DNA metabolic process
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	0016787	molecular_function	hydrolase activity
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0008270	molecular_function	zinc ion binding
T	0019843	molecular_function	rRNA binding
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0046677	biological_process	response to antibiotic
T	0070181	molecular_function	small ribosomal subunit rRNA binding
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015935	cellular_component	small ribosomal subunit
W	0000028	biological_process	ribosomal small subunit assembly
W	0002181	biological_process	cytoplasmic translation
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0008073	molecular_function	ornithine decarboxylase inhibitor activity
W	0015935	cellular_component	small ribosomal subunit
W	0019843	molecular_function	rRNA binding
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	0070181	molecular_function	small ribosomal subunit rRNA binding
W	1990904	cellular_component	ribonucleoprotein complex
X	0000028	biological_process	ribosomal small subunit assembly
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA

Chain	Residue	Details
J	SER19-ALA45

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR

Chain	Residue	Details
K	GLY99-ARG116

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHN

Chain	Residue	Details
N	ILE96-ASN118

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
O	LYS42-ARG49

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS

Chain	Residue	Details
T	GLY55-SER67

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI

Chain	Residue	Details
U	ILE21-ILE44

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG

Chain	Residue	Details
P	PRO9-GLY37

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
V	ASN52-THR76

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL

Chain	Residue	Details
L	GLY68-LEU86

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
M	ALA29-THR44

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY

Chain	Residue	Details
R	LEU38-TYR68

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
Q	ARG62-ARG84

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
F	ALA162-GLY196

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
H	GLY27-ILE59

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV

Chain	Residue	Details
G	LEU93-VAL117

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ

Chain	Residue	Details
P	ARG86-GLN99

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA

Chain	Residue	Details
S	VAL2-ALA11

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP

Chain	Residue	Details
E	PRO158-PRO182

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN

Chain	Residue	Details
I	GLY43-ASN52

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV

Chain	Residue	Details
03	GLY1063-VAL1075

site_id	PS01181
Number of Residues	13
Details	RIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK

Chain	Residue	Details
X	ASP13-LYS25

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Region: {"description":"Required for interaction with Crp at class II promoters"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	68
Details	Domain: {"description":"KH type-2"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	60
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	63
Details	Domain: {"description":"S5 DRBM"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"3-methylthioaspartic acid","evidences":[{"source":"PubMed","id":"8844851","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	13
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)