6AU0

Crystal structure of PPK2 (Class III) in complex with bisphosphonate inhibitor (2-((3,5-dichlorophenyl)amino)ethane-1,1-diyl)diphosphonic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006797	biological_process	polyphosphate metabolic process
A	0008976	molecular_function	polyphosphate kinase activity
A	0016776	molecular_function	phosphotransferase activity, phosphate group as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue BWJ A 401

Chain	Residue
A	ALA78
A	ASP222
A	HOH559
A	HOH561
A	ALA79
A	GLY80
A	LYS81
A	ASP82
A	GLY83
A	ARG204
A	PHE205
A	ARG208

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 402

Chain	Residue
A	HIS195
A	SER197
A	LYS198
A	TRP229
A	ARG233
A	HOH509
A	HOH544

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site_id	AC3
Number of Residues	7
Details	binding site for residue GOL A 403

Chain	Residue
A	TYR114
A	SER155
A	PHE167
A	ARG171
A	GLN174
A	GLU184
A	ASN185

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