6ARB

CRYSTAL STRUCTURE OF PROTEIN CitE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MAGNESIUM, PYRUVATE AND COENZYME A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0006107	biological_process	oxaloacetate metabolic process
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0006107	biological_process	oxaloacetate metabolic process
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0006107	biological_process	oxaloacetate metabolic process
C	0016829	molecular_function	lyase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 301

Chain	Residue
A	GLU120
A	ASP146
A	PYR302
A	HOH407
A	HOH409

---

site_id	AC2
Number of Residues	10
Details	binding site for residue PYR A 302

Chain	Residue
A	GLU145
A	ASP146
A	MG301
A	HOH414
A	HOH485
C	HOH432
A	ARG72
A	GLU120
A	GLY143
A	ALA144

---

site_id	AC3
Number of Residues	15
Details	binding site for residue COA A 303

Chain	Residue
A	PHE20
A	CYS21
A	PRO22
A	ARG28
A	ASP42
A	ARG72
A	ILE217
A	HIS218
A	PRO219
A	HOH512
B	ARG240
C	ALA252
C	MET259
C	ASP261
C	HOH432

---

site_id	AC4
Number of Residues	5
Details	binding site for residue PO4 A 304

Chain	Residue
A	ARG158
A	ARG168
B	ARG158
B	ARG168
C	ARG168

---

site_id	AC5
Number of Residues	3
Details	binding site for residue PO4 A 305

Chain	Residue
A	THR78
A	ALA79
A	HOH435

---

site_id	AC6
Number of Residues	7
Details	binding site for residue GOL A 306

Chain	Residue
A	GLU145
A	SER155
A	SER156
A	ARG157
A	HOH410
C	VAL264
C	HIS267

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL A 307

Chain	Residue
A	ARG204
A	ASP205
A	LYS235
A	HOH429
B	ALA159
B	ARG164

---

site_id	AC8
Number of Residues	5
Details	binding site for residue MG B 301

Chain	Residue
B	GLU120
B	ASP146
B	PYR302
B	HOH410
B	HOH445

---

site_id	AC9
Number of Residues	11
Details	binding site for residue PYR B 302

Chain	Residue
B	ARG72
B	GLU120
B	GLY143
B	ALA144
B	GLU145
B	ASP146
B	MG301
B	HOH416
B	HOH473
B	HOH486
B	HOH531

---

site_id	AD1
Number of Residues	16
Details	binding site for residue COA B 303

Chain	Residue
A	ALA252
A	MET259
A	ASP261
B	PHE20
B	CYS21
B	PRO22
B	ARG28
B	LYS31
B	ASP42
B	ARG72
B	ILE217
B	HIS218
B	PRO219
B	HOH401
B	HOH473
C	ARG240

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL B 304

Chain	Residue
A	HIS267
B	GLU145
B	SER155
B	SER156
B	ARG157
B	HOH403

---

site_id	AD3
Number of Residues	5
Details	binding site for residue MG C 301

Chain	Residue
C	GLU120
C	ASP146
C	PYR302
C	HOH406
C	HOH423

---

site_id	AD4
Number of Residues	9
Details	binding site for residue PYR C 302

Chain	Residue
C	ASP146
C	MG301
C	HOH424
C	HOH491
C	ARG72
C	GLU120
C	GLY143
C	ALA144
C	GLU145

---

site_id	AD5
Number of Residues	15
Details	binding site for residue COA C 303

Chain	Residue
A	ARG240
B	MET259
B	HOH464
C	PHE20
C	CYS21
C	PRO22
C	ARG25
C	ARG28
C	LYS31
C	ASP42
C	ARG72
C	ILE217
C	HIS218
C	PRO219
C	HOH422

---

site_id	AD6
Number of Residues	4
Details	binding site for residue PO4 C 304

Chain	Residue
C	ARG230
C	HIS233
C	LEU236
C	ARG240

---

site_id	AD7
Number of Residues	7
Details	binding site for residue GOL C 305

Chain	Residue
B	HIS267
C	GLU145
C	SER155
C	SER156
C	ARG157
C	HOH402
C	HOH405

---

site_id	AD8
Number of Residues	3
Details	binding site for residue GOL C 306

Chain	Residue
C	ALA159
C	ARG164
C	HOH415

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING:

Chain	Residue	Details
A	ARG72
A	GLU120
A	ASP146
B	ARG72
B	GLU120
B	ASP146
C	ARG72
C	GLU120
C	ASP146

---