Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004013 | molecular_function | adenosylhomocysteinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0033353 | biological_process | S-adenosylmethionine cycle |
| A | 0071269 | biological_process | L-homocysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue NAD A 500 |
| Chain | Residue |
| A | THR162 |
| A | GLU248 |
| A | ILE249 |
| A | ASP250 |
| A | CYS253 |
| A | THR280 |
| A | THR281 |
| A | GLY282 |
| A | ASN283 |
| A | ILE286 |
| A | ILE304 |
| A | THR163 |
| A | GLY305 |
| A | HIS306 |
| A | ASN351 |
| A | HIS358 |
| A | LYS431 |
| A | TYR435 |
| A | ADN501 |
| A | HOH640 |
| A | HOH656 |
| A | HOH687 |
| A | THR164 |
| A | HOH760 |
| A | HOH838 |
| A | HOH887 |
| A | ASN196 |
| A | GLY225 |
| A | GLY227 |
| A | ASP228 |
| A | VAL229 |
| A | THR247 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue ADN A 501 |
| Chain | Residue |
| A | LEU57 |
| A | HIS58 |
| A | THR60 |
| A | GLN62 |
| A | THR63 |
| A | ASP136 |
| A | GLU161 |
| A | THR162 |
| A | LYS191 |
| A | ASP195 |
| A | HIS306 |
| A | THR356 |
| A | GLY357 |
| A | HIS358 |
| A | MET363 |
| A | NAD500 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MPD A 502 |
| Chain | Residue |
| A | GLU417 |
| A | GLU417 |
| A | LYS420 |
| A | LYS420 |
Functional Information from PROSITE/UniProt
| site_id | PS00738 |
| Number of Residues | 15 |
| Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDhAAAAI |
| Chain | Residue | Details |
| A | SER81-ILE95 | |
| site_id | PS00739 |
| Number of Residues | 18 |
| Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKrvvVcGFGdVGKGtaA |
| Chain | Residue | Details |
| A | GLY218-ALA235 | |
