Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | HIS0 |
| A | MET1 |
| A | ASN2 |
| A | ILE230 |
| A | SER231 |
| A | ARG279 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | GLU83 |
| A | HOH665 |
| A | THR22 |
| A | TYR30 |
| A | ALA81 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASP98 |
| A | HIS99 |
| A | ASP224 |
| A | HIS269 |
| A | HOH606 |
| A | HOH746 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | HIS94 |
| A | HIS96 |
| A | HIS205 |
| A | ASP224 |
| A | HOH606 |
| A | HOH764 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 405 |
| Chain | Residue |
| A | GLU108 |
| A | HOH528 |
| A | HOH807 |
| C | HIS277 |
| C | HOH615 |
| C | HOH731 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | HIS0 |
| B | MET1 |
| B | ASN2 |
| B | ILE230 |
| B | SER231 |
| B | ARG279 |
| B | HIS286 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | THR22 |
| B | TYR30 |
| B | TRP58 |
| B | ALA81 |
| B | GLU83 |
| B | HOH678 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| B | HIS94 |
| B | HIS96 |
| B | HIS205 |
| B | ASP224 |
| B | HOH573 |
| B | HOH742 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 404 |
| Chain | Residue |
| B | ASP98 |
| B | HIS99 |
| B | ASP224 |
| B | HIS269 |
| B | HOH573 |
| B | HOH739 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 405 |
| Chain | Residue |
| A | HOH501 |
| A | HOH666 |
| B | HOH569 |
| B | HOH819 |
| C | HOH513 |
| C | HOH661 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 406 |
| Chain | Residue |
| B | HIS277 |
| B | HOH728 |
| B | HOH780 |
| D | GLU108 |
| D | HOH621 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 407 |
| Chain | Residue |
| A | ASP300 |
| A | HOH760 |
| B | HIS6 |
| B | HOH579 |
| B | HOH619 |
| B | HOH769 |
| D | HOH575 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 408 |
| Chain | Residue |
| B | GLU157 |
| B | HOH502 |
| C | HOH535 |
| D | HOH504 |
| D | HOH628 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 409 |
| Chain | Residue |
| A | HOH595 |
| B | MET16 |
| B | HOH523 |
| B | HOH617 |
| B | HOH659 |
| B | HOH729 |
| B | HOH841 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 401 |
| Chain | Residue |
| C | HIS0 |
| C | MET1 |
| C | ASN2 |
| C | ILE230 |
| C | SER231 |
| C | ARG279 |
| C | HIS286 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 402 |
| Chain | Residue |
| C | ASP98 |
| C | HIS99 |
| C | ASP224 |
| C | HIS269 |
| C | HOH636 |
| C | HOH677 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 403 |
| Chain | Residue |
| C | HIS205 |
| C | ASP224 |
| C | HOH636 |
| C | HOH698 |
| C | HIS94 |
| C | HIS96 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue CA C 404 |
| Chain | Residue |
| A | HOH539 |
| A | HOH823 |
| B | HOH504 |
| C | ASN165 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 405 |
| Chain | Residue |
| A | HOH685 |
| A | HOH768 |
| C | HIS6 |
| C | HOH531 |
| C | HOH571 |
| D | ASP300 |
| D | HOH649 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue CA C 406 |
| Chain | Residue |
| C | HOH507 |
| D | HOH539 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| D | HIS0 |
| D | MET1 |
| D | ASN2 |
| D | ILE230 |
| D | SER231 |
| D | ARG279 |
| D | HIS286 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 402 |
| Chain | Residue |
| D | THR22 |
| D | TRP58 |
| D | ALA81 |
| D | GLU83 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 403 |
| Chain | Residue |
| D | ASP98 |
| D | HIS99 |
| D | ASP224 |
| D | HIS269 |
| D | HOH579 |
| D | HOH675 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 404 |
| Chain | Residue |
| D | HIS94 |
| D | HIS96 |
| D | HIS205 |
| D | ASP224 |
| D | HOH579 |
| D | HOH638 |
