6AMV
Abl 1b Regulatory Module 'inhibiting state'
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | SER248 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Breakpoint for translocation to form BCR-ABL and NUP214-ABL1 fusion proteins => ECO:0000269|PubMed:15361874, ECO:0000269|PubMed:3021337 |
| Chain | Residue | Details |
| A | HIS45 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:16543148, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332 |
| Chain | Residue | Details |
| A | SER69 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16912036, ECO:0000269|PubMed:18775435 |
| Chain | Residue | Details |
| A | TYR89 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:16912036 |
| Chain | Residue | Details |
| A | TYR134 | |
| A | TYR147 | |
| A | TYR158 | |
| A | TYR191 | |
| A | TYR204 | |
| A | TYR234 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16912036 |
| Chain | Residue | Details |
| A | TYR245 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P42684 |
| Chain | Residue | Details |
| A | SER248 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | LYS253 |
