6AID
Structural insights into the unique polylactate degrading mechanism of Thermobifida alba cutinase
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | GLU213 |
| A | ASP243 |
| A | GLU292 |
| A | HOH622 |
| A | HOH654 |
| A | HOH661 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | HOH597 |
| A | HOH625 |
| A | HOH690 |
| A | VAL63 |
| A | ASP149 |
| A | ALA150 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ARG70 |
| A | ALA73 |
| A | PHE76 |
| A | HOH556 |
| A | HOH628 |
| A | HOH696 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue 9YL A 404 |
| Chain | Residue |
| A | GLY98 |
| A | TYR99 |
| A | SER169 |
| A | SER233 |
| A | HIS247 |
| A | PHE248 |
| A | LAC407 |
| A | HOH550 |
| A | HOH593 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 405 |
| Chain | Residue |
| A | PRO193 |
| A | ALA218 |
| A | HIS223 |
| A | SER224 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 406 |
| Chain | Residue |
| A | ALA212 |
| A | GLU213 |
| A | ASP215 |
| A | SER219 |
| A | VAL220 |
| A | HOH686 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue LAC A 407 |
| Chain | Residue |
| A | TYR99 |
| A | MET170 |
| A | TRP194 |
| A | ILE217 |
| A | 9YL404 |
| A | HOH550 |
Functional Information from PROSITE/UniProt
| site_id | PS00120 |
| Number of Residues | 10 |
| Details | LIPASE_SER Lipases, serine active site. LAVMGHSMGG |
| Chain | Residue | Details |
| A | LEU163-GLY172 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"30761732","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"30761732","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A0K8P6T7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30761732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3WYN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AID","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
