Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001533 | cellular_component | cornified envelope |
| A | 0002803 | biological_process | positive regulation of antibacterial peptide production |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030141 | cellular_component | secretory granule |
| A | 0097209 | cellular_component | epidermal lamellar body |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 9YO A 301 |
| Chain | Residue |
| A | HIS57 |
| A | THR217 |
| A | TYR218 |
| A | CYS220 |
| A | HIS99 |
| A | ASP102 |
| A | THR190 |
| A | ASN192 |
| A | SER195 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue TRS A 302 |
| Chain | Residue |
| A | CYS22 |
| A | LYS23 |
| A | GLU24 |
| A | ASP71 |
| A | LYS72 |
| A | PRO92 |
| A | ASP154 |
| A | HOH402 |
| A | HOH446 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | GLN76 |
| A | ARG90 |
| A | TYR94 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 304 |
| Chain | Residue |
| A | LYS23 |
| A | LYS59 |
| A | SER88 |
| A | ARG90 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. NTcnGDSGGPLV |
| Chain | Residue | Details |
| A | ASN189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Major binding site for inhibitory zinc or copper => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS99 | |
