Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005774 | cellular_component | vacuolar membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0009678 | molecular_function | diphosphate hydrolysis-driven proton transmembrane transporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005774 | cellular_component | vacuolar membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0009678 | molecular_function | diphosphate hydrolysis-driven proton transmembrane transporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue PO4 A 1001 |
| Chain | Residue |
| A | LYS250 |
| A | ASP731 |
| A | PO41002 |
| A | MG1005 |
| A | MG1006 |
| A | MG1007 |
| A | K1008 |
| A | HOH1127 |
| A | HOH1138 |
| A | ASP253 |
| A | ASP283 |
| A | ASP287 |
| A | ASP507 |
| A | ASN534 |
| A | ASP691 |
| A | ASP727 |
| A | LYS730 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue PO4 A 1002 |
| Chain | Residue |
| A | ASP253 |
| A | GLU268 |
| A | ASP507 |
| A | ASP691 |
| A | LYS694 |
| A | PO41001 |
| A | MG1003 |
| A | MG1004 |
| A | MG1005 |
| A | MG1006 |
| A | MG1007 |
| A | HOH1101 |
| A | HOH1108 |
| A | HOH1117 |
| A | HOH1137 |
| A | HOH1138 |
| A | HOH1150 |
| A | HOH1205 |
| A | HOH1228 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 1003 |
| Chain | Residue |
| A | ASP253 |
| A | ASP257 |
| A | PO41002 |
| A | MG1005 |
| A | HOH1109 |
| A | HOH1117 |
| A | HOH1137 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 1004 |
| Chain | Residue |
| A | ASP507 |
| A | PO41002 |
| A | MG1006 |
| A | HOH1101 |
| A | HOH1108 |
| A | HOH1132 |
| A | HOH1228 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue MG A 1005 |
| Chain | Residue |
| A | ASP253 |
| A | ASP727 |
| A | LYS730 |
| A | PO41001 |
| A | PO41002 |
| A | MG1003 |
| A | HOH1117 |
| A | HOH1127 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 1006 |
| Chain | Residue |
| A | ASP283 |
| A | ASP507 |
| A | PO41001 |
| A | PO41002 |
| A | MG1004 |
| A | HOH1108 |
| A | HOH1205 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1007 |
| Chain | Residue |
| A | ASN534 |
| A | ASP691 |
| A | PO41001 |
| A | PO41002 |
| A | HOH1138 |
| A | HOH1150 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue K A 1008 |
| Chain | Residue |
| A | GLY533 |
| A | ASN534 |
| A | PO41001 |
| A | HOH1181 |
| A | HOH1193 |
| A | HOH1215 |
| A | HOH1264 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue 1PG A 1009 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue 1PG A 1010 |
| Chain | Residue |
| A | PHE766 |
| B | PHE471 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue 1PG A 1011 |
| site_id | AD3 |
| Number of Residues | 19 |
| Details | binding site for residue PO4 B 1001 |
| Chain | Residue |
| B | HOH1128 |
| B | HOH1179 |
| B | LYS250 |
| B | ASP253 |
| B | ASP283 |
| B | ASP287 |
| B | ASP507 |
| B | ASN534 |
| B | ASP691 |
| B | ASP727 |
| B | LYS730 |
| B | ASP731 |
| B | PO41002 |
| B | MG1005 |
| B | MG1006 |
| B | MG1007 |
| B | K1008 |
| B | HOH1112 |
| B | HOH1113 |
| site_id | AD4 |
| Number of Residues | 19 |
| Details | binding site for residue PO4 B 1002 |
| Chain | Residue |
| B | ASP253 |
| B | GLU268 |
| B | ASP507 |
| B | ASP691 |
| B | LYS694 |
| B | PO41001 |
| B | MG1003 |
| B | MG1004 |
| B | MG1005 |
| B | MG1006 |
| B | MG1007 |
| B | HOH1101 |
| B | HOH1111 |
| B | HOH1128 |
| B | HOH1134 |
| B | HOH1142 |
| B | HOH1156 |
| B | HOH1175 |
| B | HOH1179 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 1003 |
| Chain | Residue |
| B | ASP253 |
| B | ASP257 |
| B | PO41002 |
| B | MG1005 |
| B | HOH1101 |
| B | HOH1120 |
| B | HOH1156 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 1004 |
| Chain | Residue |
| B | ASP507 |
| B | PO41002 |
| B | MG1006 |
| B | HOH1111 |
| B | HOH1121 |
| B | HOH1142 |
| B | HOH1175 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue MG B 1005 |
| Chain | Residue |
| B | ASP253 |
| B | ASP727 |
| B | LYS730 |
| B | PO41001 |
| B | PO41002 |
| B | MG1003 |
| B | HOH1113 |
| B | HOH1156 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 1006 |
| Chain | Residue |
| B | ASP283 |
| B | ASP507 |
| B | PO41001 |
| B | PO41002 |
| B | MG1004 |
| B | HOH1111 |
| B | HOH1179 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1007 |
| Chain | Residue |
| B | ASN534 |
| B | ASP691 |
| B | PO41001 |
| B | PO41002 |
| B | HOH1128 |
| B | HOH1134 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue K B 1008 |
| Chain | Residue |
| B | ASN534 |
| B | PO41001 |
| B | HOH1128 |
| B | HOH1167 |
| B | HOH1202 |
| B | HOH1205 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue 1PG B 1009 |
| Chain | Residue |
| B | MET592 |
| B | PRO644 |
| B | LEU648 |
| B | THR652 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue 1PG B 1010 |
| Chain | Residue |
| A | PHE471 |
| A | HOH1220 |
| B | LEU762 |
| B | PHE766 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue 1PG B 1011 |
| Chain | Residue |
| B | LYS457 |
| B | PHE464 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 148 |
| Details | Topological domain: {"description":"Intravacuolar","evidences":[{"source":"PubMed","id":"22456709","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 850 |
| Details | Transmembrane: {"description":"Helical"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 370 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"22456709","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22456709","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Site: {"description":"Important for proton transport","evidences":[{"evidenceCode":"ECO:0000305"}]} |
