6AEL
Crystal structure of ENPP1 in complex with 3'3'-cGAMP
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: AMP-threonine intermediate => ECO:0000269|PubMed:11027689 |
| Chain | Residue | Details |
| A | ALA238 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23027977, ECO:0000269|PubMed:23041369, ECO:0000269|PubMed:30356045 |
| Chain | Residue | Details |
| A | ASP200 | |
| A | ASP358 | |
| A | HIS362 | |
| A | ASP405 | |
| A | HIS406 | |
| A | HIS517 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23027977, ECO:0000269|PubMed:23041369 |
| Chain | Residue | Details |
| A | ALA238 | |
| A | PHE781 | |
| A | TYR783 | |
| A | GLY785 | |
| A | TYR787 | |
| A | SER789 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23027977, ECO:0007744|PDB:4GTY |
| Chain | Residue | Details |
| A | ASN259 | |
| A | LEU272 | |
| A | LYS277 | |
| A | TYR322 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30356045 |
| Chain | Residue | Details |
| A | SER514 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Essential for catalytic activity => ECO:0000250|UniProtKB:Q9R1E6 |
| Chain | Residue | Details |
| A | THR896 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q924C3 |
| Chain | Residue | Details |
| A | ALA238 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19656770, ECO:0000269|PubMed:23027977 |
| Chain | Residue | Details |
| A | ASN267 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19656770, ECO:0000269|PubMed:23027977, ECO:0000269|PubMed:23041369 |
| Chain | Residue | Details |
| A | ASN323 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:23041369 |
| Chain | Residue | Details |
| A | ASN459 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:23027977, ECO:0000269|PubMed:23041369 |
| Chain | Residue | Details |
| A | ASN567 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19656770, ECO:0000269|PubMed:23041369 |
| Chain | Residue | Details |
| A | ASN624 |
