6ADQ
Respiratory Complex CIII2CIV2SOD2 from Mycobacterium smegmatis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0022904 | biological_process | respiratory electron transport chain |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0016020 | cellular_component | membrane |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0020037 | molecular_function | heme binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0016020 | cellular_component | membrane |
| E | 0004129 | molecular_function | cytochrome-c oxidase activity |
| E | 0005507 | molecular_function | copper ion binding |
| E | 0016020 | cellular_component | membrane |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0042773 | biological_process | ATP synthesis coupled electron transport |
| E | 0046872 | molecular_function | metal ion binding |
| E | 1902600 | biological_process | proton transmembrane transport |
| F | 0004129 | molecular_function | cytochrome-c oxidase activity |
| F | 0009060 | biological_process | aerobic respiration |
| F | 0015990 | biological_process | electron transport coupled proton transport |
| F | 0016020 | cellular_component | membrane |
| F | 0020037 | molecular_function | heme binding |
| G | 0004129 | molecular_function | cytochrome-c oxidase activity |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0009055 | molecular_function | electron transfer activity |
| G | 0009060 | biological_process | aerobic respiration |
| G | 0016020 | cellular_component | membrane |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0019646 | biological_process | aerobic electron transport chain |
| G | 0022904 | biological_process | respiratory electron transport chain |
| G | 1902600 | biological_process | proton transmembrane transport |
| H | 0004129 | molecular_function | cytochrome-c oxidase activity |
| H | 0005886 | cellular_component | plasma membrane |
| H | 0016020 | cellular_component | membrane |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0022900 | biological_process | electron transport chain |
| H | 1902600 | biological_process | proton transmembrane transport |
| I | 0016020 | cellular_component | membrane |
| M | 0005886 | cellular_component | plasma membrane |
| M | 0016491 | molecular_function | oxidoreductase activity |
| M | 0046872 | molecular_function | metal ion binding |
| M | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| N | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| N | 0009055 | molecular_function | electron transfer activity |
| N | 0016020 | cellular_component | membrane |
| N | 0016491 | molecular_function | oxidoreductase activity |
| N | 0022904 | biological_process | respiratory electron transport chain |
| N | 1902600 | biological_process | proton transmembrane transport |
| O | 0005506 | molecular_function | iron ion binding |
| O | 0005886 | cellular_component | plasma membrane |
| O | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| O | 0009055 | molecular_function | electron transfer activity |
| O | 0016020 | cellular_component | membrane |
| O | 0016491 | molecular_function | oxidoreductase activity |
| O | 0020037 | molecular_function | heme binding |
| O | 0046872 | molecular_function | metal ion binding |
| O | 1902600 | biological_process | proton transmembrane transport |
| P | 0016020 | cellular_component | membrane |
| Q | 0004129 | molecular_function | cytochrome-c oxidase activity |
| Q | 0005507 | molecular_function | copper ion binding |
| Q | 0016020 | cellular_component | membrane |
| Q | 0016491 | molecular_function | oxidoreductase activity |
| Q | 0042773 | biological_process | ATP synthesis coupled electron transport |
| Q | 0046872 | molecular_function | metal ion binding |
| Q | 1902600 | biological_process | proton transmembrane transport |
| R | 0004129 | molecular_function | cytochrome-c oxidase activity |
| R | 0009060 | biological_process | aerobic respiration |
| R | 0015990 | biological_process | electron transport coupled proton transport |
| R | 0016020 | cellular_component | membrane |
| R | 0020037 | molecular_function | heme binding |
| S | 0004129 | molecular_function | cytochrome-c oxidase activity |
| S | 0005886 | cellular_component | plasma membrane |
| S | 0009055 | molecular_function | electron transfer activity |
| S | 0009060 | biological_process | aerobic respiration |
| S | 0016020 | cellular_component | membrane |
| S | 0016491 | molecular_function | oxidoreductase activity |
| S | 0019646 | biological_process | aerobic electron transport chain |
| S | 0022904 | biological_process | respiratory electron transport chain |
| S | 1902600 | biological_process | proton transmembrane transport |
| T | 0004129 | molecular_function | cytochrome-c oxidase activity |
| T | 0005886 | cellular_component | plasma membrane |
| T | 0016020 | cellular_component | membrane |
| T | 0016491 | molecular_function | oxidoreductase activity |
| T | 0022900 | biological_process | electron transport chain |
| T | 1902600 | biological_process | proton transmembrane transport |
| U | 0016020 | cellular_component | membrane |
| Y | 0005507 | molecular_function | copper ion binding |
| Y | 0006801 | biological_process | superoxide metabolic process |
| Y | 0046872 | molecular_function | metal ion binding |
| Z | 0005507 | molecular_function | copper ion binding |
| Z | 0006801 | biological_process | superoxide metabolic process |
| Z | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CU E 401 |
| Chain | Residue |
| E | HIS232 |
| E | CYS273 |
| E | CYS277 |
| E | HIS281 |
| E | MET284 |
| E | CU402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CU E 402 |
| Chain | Residue |
| E | MET284 |
| E | CU401 |
| E | HIS232 |
| E | CYS273 |
| E | CYS277 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for residue HEA F 601 |
| Chain | Residue |
| F | TRP260 |
| F | VAL267 |
| F | TYR268 |
| F | ILE270 |
| F | ALA271 |
| F | HIS313 |
| F | HIS314 |
| F | THR337 |
| F | PHE342 |
| F | GLY373 |
| F | GLY376 |
| F | VAL377 |
| F | LEU379 |
| F | ALA380 |
| F | ASP385 |
| F | THR389 |
| F | VAL394 |
| F | HIS397 |
| F | PHE398 |
| F | VAL401 |
| F | LEU402 |
| F | THR405 |
| F | ARG459 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | binding site for residue HEA F 602 |
| Chain | Residue |
| F | PHE52 |
| F | GLY56 |
| F | LEU57 |
| F | MET62 |
| F | ARG63 |
| F | PHE79 |
| F | PHE83 |
| F | HIS86 |
| F | MET90 |
| F | LEU91 |
| F | GLY150 |
| F | TRP151 |
| F | TYR392 |
| F | ILE395 |
| F | PHE398 |
| F | HIS399 |
| F | LEU402 |
| F | PHE403 |
| F | ILE406 |
| F | PHE446 |
| F | ARG459 |
| F | ARG460 |
| F | LEU484 |
| F | GLY485 |
| F | MET488 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CU F 603 |
| Chain | Residue |
| F | HIS264 |
| F | HIS313 |
| F | HIS314 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CU F 604 |
| Chain | Residue |
| E | GLU275 |
| F | TYR154 |
| F | ASP390 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue CDL F 605 |
| Chain | Residue |
| F | PHE118 |
| F | PRO119 |
| F | ARG120 |
| F | LEU121 |
| F | LEU124 |
| G | ARG15 |
| G | VAL25 |
| G | TRP32 |
| G | GLU36 |
| G | LEU149 |
| G | GLY153 |
| G | LEU160 |
| G | ARG164 |
| G | ALA177 |
| G | VAL180 |
| G | TYR184 |
| H | ALA86 |
| H | VAL129 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | binding site for residue CDL F 606 |
| Chain | Residue |
| F | VAL495 |
| F | PHE496 |
| F | TRP499 |
| F | ARG500 |
| B | PHE424 |
| B | ARG428 |
| D | CDL201 |
| F | MET21 |
| F | GLY22 |
| F | PRO23 |
| F | GLY25 |
| F | ASN26 |
| F | LEU27 |
| F | ILE28 |
| F | ILE42 |
| F | CYS45 |
| F | PHE49 |
| F | TRP127 |
| F | ILE414 |
| F | PHE418 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue 9Y0 G 301 |
| Chain | Residue |
| F | ALA236 |
| G | THR130 |
| G | ILE131 |
| G | TYR141 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue CDL H 201 |
| Chain | Residue |
| A | CDL502 |
| B | ARG487 |
| B | LYS490 |
| B | CDL605 |
| C | TRP289 |
| C | ARG293 |
| H | TRP91 |
| H | THR123 |
| H | CYS126 |
| H | TRP134 |
| H | GLY135 |
| site_id | AD2 |
| Number of Residues | 15 |
| Details | binding site for residue CDL D 201 |
| Chain | Residue |
| B | MET415 |
| B | TYR423 |
| B | PHE424 |
| B | ARG428 |
| D | ILE45 |
| D | MET48 |
| D | GLY51 |
| D | VAL87 |
| D | GLY88 |
| D | ARG89 |
| D | ASN90 |
| D | ARG94 |
| D | TRP98 |
| F | MET21 |
| F | CDL606 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue 9Y0 D 202 |
| Chain | Residue |
| B | TYR347 |
| B | VAL354 |
| D | MET43 |
| D | PRO44 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue PLM Y 301 |
| Chain | Residue |
| B | TRP318 |
| B | GLU319 |
| D | ARG64 |
| Y | CYS21 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue 9XX Y 302 |
| Chain | Residue |
| B | PHE320 |
| B | TYR321 |
| B | TRP332 |
| Y | CYS21 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue 9Y0 K 201 |
| Chain | Residue |
| D | VAL68 |
| D | HIS70 |
| D | VAL71 |
| F | PHE61 |
| F | PHE73 |
| K | GLN28 |
| K | ILE29 |
| K | 9YF202 |
| K | 9XX204 |
| site_id | AD7 |
| Number of Residues | 18 |
| Details | binding site for residue 9YF K 202 |
| Chain | Residue |
| B | PHE389 |
| B | ASN405 |
| B | ALA406 |
| B | TRP409 |
| B | ILE410 |
| B | LEU418 |
| B | CDL604 |
| C | SER203 |
| D | VAL71 |
| D | GLU72 |
| D | PHE75 |
| D | PHE79 |
| K | CYS24 |
| K | SER25 |
| K | ILE29 |
| K | GLN31 |
| K | 9Y0201 |
| K | 9XX204 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue PLM K 203 |
| Chain | Residue |
| F | PHE61 |
| F | GLN81 |
| F | PHE140 |
| F | PRO143 |
| K | CYS24 |
| K | SER25 |
| K | ALA26 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue 9XX K 204 |
| Chain | Residue |
| D | VAL71 |
| D | TRP74 |
| D | PHE75 |
| F | LEU134 |
| F | ILE137 |
| F | ILE141 |
| K | CYS24 |
| K | 9Y0201 |
| K | 9YF202 |
| site_id | AE1 |
| Number of Residues | 19 |
| Details | binding site for residue HEM B 601 |
| Chain | Residue |
| B | PHE40 |
| B | GLY43 |
| B | PHE116 |
| B | ILE120 |
| B | HIS123 |
| B | LEU124 |
| B | ARG126 |
| B | ILE127 |
| B | ALA132 |
| B | ASN140 |
| B | TRP141 |
| B | GLY144 |
| B | SER145 |
| B | LEU147 |
| B | HIS226 |
| B | VAL230 |
| B | HIS235 |
| B | THR236 |
| B | MQ9609 |
| site_id | AE2 |
| Number of Residues | 23 |
| Details | binding site for residue HEM B 602 |
| Chain | Residue |
| B | PHE50 |
| B | LEU53 |
| B | GLY57 |
| B | VAL58 |
| B | LEU60 |
| B | THR61 |
| B | PHE64 |
| B | ARG106 |
| B | HIS109 |
| B | HIS110 |
| B | ALA113 |
| B | PHE116 |
| B | GLU154 |
| B | GLY158 |
| B | TYR159 |
| B | LEU161 |
| B | PRO162 |
| B | TYR208 |
| B | HIS211 |
| B | ILE212 |
| B | ILE219 |
| B | ASN282 |
| N | LEU213 |
| site_id | AE3 |
| Number of Residues | 18 |
| Details | binding site for residue CDL B 604 |
| Chain | Residue |
| B | HIS37 |
| B | TRP38 |
| B | PHE129 |
| B | ARG366 |
| B | PRO367 |
| B | ARG368 |
| B | THR374 |
| B | SER378 |
| B | PHE389 |
| B | VAL422 |
| B | ALA426 |
| B | TRP429 |
| B | ALA430 |
| B | CDL605 |
| C | MET288 |
| C | ARG293 |
| C | MQ9304 |
| K | 9YF202 |
| site_id | AE4 |
| Number of Residues | 14 |
| Details | binding site for residue CDL B 605 |
| Chain | Residue |
| B | ARG368 |
| B | TRP429 |
| B | LEU433 |
| B | PRO483 |
| B | LEU484 |
| B | LYS486 |
| B | CDL604 |
| C | ARG293 |
| F | TYR29 |
| F | ILE32 |
| H | TRP90 |
| H | TRP91 |
| H | SER98 |
| H | CDL201 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue MQ9 B 607 |
| Chain | Residue |
| A | PHE136 |
| B | THR56 |
| B | SER261 |
| B | GLY262 |
| B | PHE265 |
| B | CDL603 |
| B | MQ9609 |
| M | PHE215 |
| site_id | AE6 |
| Number of Residues | 12 |
| Details | binding site for residue MQ9 B 608 |
| Chain | Residue |
| B | PHE389 |
| B | ILE395 |
| B | ILE396 |
| B | THR407 |
| C | GLY264 |
| C | PHE266 |
| C | PRO270 |
| C | MET273 |
| C | 9YF303 |
| F | ALA138 |
| H | VAL104 |
| H | TRP112 |
| site_id | AE7 |
| Number of Residues | 10 |
| Details | binding site for residue MQ9 B 609 |
| Chain | Residue |
| B | GLU44 |
| B | TYR48 |
| B | LEU220 |
| B | LEU227 |
| B | TRP231 |
| B | HEM601 |
| B | MQ9607 |
| B | 9Y0612 |
| N | PHE153 |
| N | ILE215 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue MQ9 B 610 |
| Chain | Residue |
| B | ALA174 |
| B | LEU175 |
| B | ILE178 |
| B | ILE182 |
| B | ALA334 |
| B | MET337 |
| N | CDL601 |
| site_id | AE9 |
| Number of Residues | 8 |
| Details | binding site for residue CDL B 611 |
| Chain | Residue |
| B | GLN12 |
| B | ILE16 |
| B | ARG19 |
| N | GLU138 |
| N | ALA139 |
| N | ALA346 |
| N | PHE349 |
| N | MQ9610 |
| site_id | AF1 |
| Number of Residues | 20 |
| Details | binding site for residue HEC C 301 |
| Chain | Residue |
| A | GLN359 |
| C | SER86 |
| C | CYS87 |
| C | CYS90 |
| C | HIS91 |
| C | PRO103 |
| C | LEU105 |
| C | THR108 |
| C | ALA112 |
| C | VAL117 |
| C | MET122 |
| C | PRO123 |
| C | ALA124 |
| C | LEU146 |
| C | PRO226 |
| C | GLN227 |
| E | TRP138 |
| K | GLN35 |
| K | PRO37 |
| K | ALA38 |
| site_id | AF2 |
| Number of Residues | 22 |
| Details | binding site for residue HEC C 302 |
| Chain | Residue |
| A | TYR356 |
| C | PHE115 |
| C | THR119 |
| C | ARG121 |
| C | GLN130 |
| C | ALA131 |
| C | CYS188 |
| C | CYS191 |
| C | HIS192 |
| C | LEU201 |
| C | TYR206 |
| C | PRO208 |
| C | ASP209 |
| C | LEU210 |
| C | ILE218 |
| C | MET222 |
| C | PRO226 |
| C | GLN227 |
| C | ASN228 |
| C | MET229 |
| C | PRO230 |
| C | PHE232 |
| site_id | AF3 |
| Number of Residues | 14 |
| Details | binding site for residue 9YF C 303 |
| Chain | Residue |
| B | LEU278 |
| B | MQ9608 |
| C | LYS197 |
| C | ASP209 |
| C | ALA253 |
| C | SER257 |
| C | GLY260 |
| C | TYR261 |
| C | GLY262 |
| C | MET273 |
| C | ILE278 |
| H | TRP112 |
| H | ALA116 |
| H | PHE120 |
| site_id | AF4 |
| Number of Residues | 14 |
| Details | binding site for residue MQ9 C 304 |
| Chain | Residue |
| B | MET121 |
| B | PHE128 |
| B | PHE303 |
| B | VAL340 |
| B | ALA380 |
| B | ILE381 |
| B | TYR384 |
| B | LEU385 |
| B | THR388 |
| B | PHE389 |
| B | MET392 |
| B | CDL604 |
| C | MET273 |
| C | TRP276 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue FES A 501 |
| Chain | Residue |
| A | CYS346 |
| A | HIS348 |
| A | CYS351 |
| A | CYS365 |
| A | CYS367 |
| A | HIS368 |
| site_id | AF6 |
| Number of Residues | 12 |
| Details | binding site for residue CDL A 502 |
| Chain | Residue |
| A | TRP92 |
| A | ILE145 |
| A | LYS153 |
| B | PHE502 |
| C | TRP289 |
| G | PHE107 |
| G | VAL159 |
| G | ALA163 |
| G | MET167 |
| H | PHE130 |
| H | LYS138 |
| H | CDL201 |
| site_id | AF7 |
| Number of Residues | 7 |
| Details | binding site for residue 9YF A 503 |
| Chain | Residue |
| A | TRP224 |
| A | TRP239 |
| A | TRP417 |
| A | GLU418 |
| A | 9YF504 |
| B | TRP188 |
| B | PRO322 |
| site_id | AF8 |
| Number of Residues | 12 |
| Details | binding site for residue 9YF A 504 |
| Chain | Residue |
| A | GLY217 |
| A | GLY218 |
| A | ILE220 |
| A | LYS221 |
| A | ASN222 |
| A | LYS225 |
| A | 9YF503 |
| B | ILE185 |
| B | TRP188 |
| N | GLU98 |
| N | VAL99 |
| N | ARG100 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue CU Q 401 |
| Chain | Residue |
| Q | HIS232 |
| Q | CYS273 |
| Q | CYS277 |
| Q | HIS281 |
| Q | MET284 |
| Q | CU402 |
| site_id | AG1 |
| Number of Residues | 5 |
| Details | binding site for residue CU Q 402 |
| Chain | Residue |
| Q | HIS232 |
| Q | CYS273 |
| Q | CYS277 |
| Q | MET284 |
| Q | CU401 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue CU R 603 |
| Chain | Residue |
| R | HIS264 |
| R | HIS313 |
| R | HIS314 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue CU R 604 |
| Chain | Residue |
| Q | GLU275 |
| R | TYR154 |
| R | ASP390 |
| site_id | AG4 |
| Number of Residues | 18 |
| Details | binding site for residue CDL R 605 |
| Chain | Residue |
| R | PHE118 |
| R | PRO119 |
| R | ARG120 |
| R | LEU121 |
| R | LEU124 |
| S | ARG15 |
| S | VAL25 |
| S | TRP32 |
| S | GLU36 |
| S | LEU149 |
| S | GLY153 |
| S | LEU160 |
| S | ARG164 |
| S | ALA177 |
| S | VAL180 |
| S | TYR184 |
| T | ALA86 |
| T | VAL129 |
| site_id | AG5 |
| Number of Residues | 19 |
| Details | binding site for residue CDL R 606 |
| Chain | Residue |
| N | PHE424 |
| N | ARG428 |
| P | CDL201 |
| R | MET21 |
| R | PRO23 |
| R | GLY25 |
| R | ASN26 |
| R | LEU27 |
| R | ILE28 |
| R | ILE42 |
| R | CYS45 |
| R | PHE49 |
| R | TRP127 |
| R | ILE414 |
| R | PHE418 |
| R | VAL495 |
| R | PHE496 |
| R | TRP499 |
| R | ARG500 |
| site_id | AG6 |
| Number of Residues | 4 |
| Details | binding site for residue 9Y0 S 301 |
| Chain | Residue |
| R | ALA236 |
| S | THR130 |
| S | ILE131 |
| S | TYR141 |
| site_id | AG7 |
| Number of Residues | 11 |
| Details | binding site for residue CDL T 201 |
| Chain | Residue |
| M | CDL503 |
| N | ARG487 |
| N | LYS490 |
| N | CDL606 |
| O | TRP289 |
| O | ARG293 |
| T | TRP91 |
| T | THR123 |
| T | CYS126 |
| T | TRP134 |
| T | GLY135 |
| site_id | AG8 |
| Number of Residues | 16 |
| Details | binding site for residue CDL P 201 |
| Chain | Residue |
| N | MET415 |
| N | TYR423 |
| N | PHE424 |
| N | ARG428 |
| P | ILE45 |
| P | MET48 |
| P | GLY51 |
| P | VAL87 |
| P | GLY88 |
| P | ARG89 |
| P | ASN90 |
| P | ARG94 |
| P | TRP98 |
| R | MET21 |
| R | PHE496 |
| R | CDL606 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue 9Y0 P 202 |
| Chain | Residue |
| N | TYR347 |
| N | VAL354 |
| P | MET43 |
| P | PRO44 |
| site_id | AH1 |
| Number of Residues | 9 |
| Details | binding site for residue 9Y0 W 201 |
| Chain | Residue |
| P | VAL68 |
| P | HIS70 |
| P | VAL71 |
| P | TRP74 |
| R | PHE73 |
| W | GLN28 |
| W | ILE29 |
| W | 9YF202 |
| W | 9XX204 |
| site_id | AH2 |
| Number of Residues | 17 |
| Details | binding site for residue 9YF W 202 |
| Chain | Residue |
| N | ASN405 |
| N | ALA406 |
| N | TRP409 |
| N | ILE410 |
| N | LEU418 |
| N | CDL605 |
| O | SER203 |
| P | VAL71 |
| P | GLU72 |
| P | PHE75 |
| P | PHE79 |
| W | CYS24 |
| W | SER25 |
| W | ILE29 |
| W | GLN31 |
| W | 9Y0201 |
| W | 9XX204 |
| site_id | AH3 |
| Number of Residues | 8 |
| Details | binding site for residue CDL N 601 |
| Chain | Residue |
| B | GLU138 |
| B | ALA139 |
| B | ALA346 |
| B | PHE349 |
| B | MQ9610 |
| N | GLN12 |
| N | ILE16 |
| N | ARG19 |
| site_id | AH4 |
| Number of Residues | 23 |
| Details | binding site for residue HEM N 603 |
| Chain | Residue |
| B | LEU213 |
| N | PHE50 |
| N | LEU53 |
| N | GLY57 |
| N | VAL58 |
| N | LEU60 |
| N | THR61 |
| N | PHE64 |
| N | ARG106 |
| N | HIS109 |
| N | HIS110 |
| N | ALA113 |
| N | PHE116 |
| N | GLU154 |
| N | GLY158 |
| N | TYR159 |
| N | LEU161 |
| N | PRO162 |
| N | TYR208 |
| N | HIS211 |
| N | ILE212 |
| N | ILE219 |
| N | ASN282 |
| site_id | AH5 |
| Number of Residues | 18 |
| Details | binding site for residue CDL N 605 |
| Chain | Residue |
| N | HIS37 |
| N | TRP38 |
| N | PHE129 |
| N | ARG366 |
| N | PRO367 |
| N | ARG368 |
| N | THR374 |
| N | SER378 |
| N | PHE389 |
| N | VAL422 |
| N | ALA426 |
| N | TRP429 |
| N | ALA430 |
| N | CDL606 |
| O | MET288 |
| O | ARG293 |
| O | MQ9304 |
| W | 9YF202 |
| site_id | AH6 |
| Number of Residues | 15 |
| Details | binding site for residue CDL N 606 |
| Chain | Residue |
| N | ARG368 |
| N | TRP429 |
| N | LEU433 |
| N | PRO483 |
| N | LEU484 |
| N | LYS486 |
| N | ARG487 |
| N | CDL605 |
| O | ARG293 |
| R | TYR29 |
| R | ILE32 |
| T | TRP90 |
| T | TRP91 |
| T | SER98 |
| T | CDL201 |
| site_id | AH7 |
| Number of Residues | 8 |
| Details | binding site for residue MQ9 N 607 |
| Chain | Residue |
| A | PHE215 |
| M | PHE136 |
| N | THR56 |
| N | SER261 |
| N | GLY262 |
| N | PHE265 |
| N | CDL604 |
| N | MQ9609 |
| site_id | AH8 |
| Number of Residues | 12 |
| Details | binding site for residue MQ9 N 608 |
| Chain | Residue |
| N | PHE389 |
| N | ILE395 |
| N | ILE396 |
| N | THR407 |
| O | GLY264 |
| O | PHE266 |
| O | PRO270 |
| O | MET273 |
| O | 9YF303 |
| R | ALA138 |
| T | VAL104 |
| T | TRP112 |
| site_id | AH9 |
| Number of Residues | 10 |
| Details | binding site for residue MQ9 N 609 |
| Chain | Residue |
| B | PHE153 |
| B | ILE215 |
| B | 9Y0606 |
| N | GLU44 |
| N | TYR48 |
| N | LEU220 |
| N | LEU227 |
| N | TRP231 |
| N | HEM602 |
| N | MQ9607 |
| site_id | AI1 |
| Number of Residues | 8 |
| Details | binding site for residue MQ9 N 610 |
| Chain | Residue |
| B | CDL611 |
| N | ALA174 |
| N | LEU175 |
| N | ILE178 |
| N | ILE182 |
| N | ALA334 |
| N | MET337 |
| N | GLY338 |
| site_id | AI2 |
| Number of Residues | 20 |
| Details | binding site for residue HEC O 301 |
| Chain | Residue |
| M | GLN359 |
| O | SER86 |
| O | CYS87 |
| O | CYS90 |
| O | HIS91 |
| O | PRO103 |
| O | LEU105 |
| O | THR108 |
| O | ALA112 |
| O | VAL117 |
| O | MET122 |
| O | PRO123 |
| O | ALA124 |
| O | LEU146 |
| O | PRO226 |
| O | GLN227 |
| Q | TRP138 |
| W | GLN35 |
| W | PRO37 |
| W | ALA38 |
| site_id | AI3 |
| Number of Residues | 22 |
| Details | binding site for residue HEC O 302 |
| Chain | Residue |
| M | TYR356 |
| O | PHE115 |
| O | THR119 |
| O | ARG121 |
| O | GLN130 |
| O | ALA131 |
| O | CYS188 |
| O | CYS191 |
| O | HIS192 |
| O | LEU201 |
| O | TYR206 |
| O | PRO208 |
| O | ASP209 |
| O | LEU210 |
| O | ILE218 |
| O | MET222 |
| O | PRO226 |
| O | GLN227 |
| O | ASN228 |
| O | MET229 |
| O | PRO230 |
| O | PHE232 |
| site_id | AI4 |
| Number of Residues | 13 |
| Details | binding site for residue 9YF O 303 |
| Chain | Residue |
| N | LEU278 |
| N | MQ9608 |
| O | LYS197 |
| O | ASP209 |
| O | ALA253 |
| O | SER257 |
| O | GLY260 |
| O | TYR261 |
| O | GLY262 |
| O | ILE278 |
| T | TRP112 |
| T | ALA116 |
| T | PHE120 |
| site_id | AI5 |
| Number of Residues | 14 |
| Details | binding site for residue MQ9 O 304 |
| Chain | Residue |
| N | MET121 |
| N | PHE128 |
| N | PHE303 |
| N | VAL340 |
| N | ALA380 |
| N | ILE381 |
| N | TYR384 |
| N | LEU385 |
| N | THR388 |
| N | PHE389 |
| N | MET392 |
| N | CDL605 |
| O | MET273 |
| O | TRP276 |
| site_id | AI6 |
| Number of Residues | 12 |
| Details | binding site for residue 9YF M 501 |
| Chain | Residue |
| B | GLU98 |
| B | VAL99 |
| B | ARG100 |
| M | GLY217 |
| M | GLY218 |
| M | ILE220 |
| M | LYS221 |
| M | ASN222 |
| M | LYS225 |
| M | 9YF504 |
| N | ILE185 |
| N | TRP188 |
| site_id | AI7 |
| Number of Residues | 6 |
| Details | binding site for residue FES M 502 |
| Chain | Residue |
| M | CYS346 |
| M | HIS348 |
| M | CYS351 |
| M | CYS365 |
| M | CYS367 |
| M | HIS368 |
| site_id | AI8 |
| Number of Residues | 13 |
| Details | binding site for residue CDL M 503 |
| Chain | Residue |
| M | TRP92 |
| M | ILE145 |
| M | LYS153 |
| N | PHE502 |
| O | TRP289 |
| S | PHE107 |
| S | VAL159 |
| S | ALA163 |
| S | LYS166 |
| S | MET167 |
| T | PHE130 |
| T | LYS138 |
| T | CDL201 |
| site_id | AI9 |
| Number of Residues | 8 |
| Details | binding site for residue 9YF M 504 |
| Chain | Residue |
| M | TRP224 |
| M | TRP239 |
| M | TRP417 |
| M | GLU418 |
| M | 9YF501 |
| N | ILE185 |
| N | TRP188 |
| N | PRO322 |
| site_id | AJ1 |
| Number of Residues | 19 |
| Details | binding site for residues CDL B 603 and 9Y0 B 606 |
| Chain | Residue |
| B | TYR20 |
| B | ALA25 |
| B | ARG28 |
| B | GLN29 |
| B | LEU213 |
| B | ILE218 |
| B | ALA221 |
| B | GLY224 |
| B | ALA225 |
| B | LEU229 |
| B | PHE232 |
| B | MQ9607 |
| B | 9Y0612 |
| N | HIS21 |
| N | ALA25 |
| N | LEU54 |
| N | VAL58 |
| N | CDL604 |
| N | MQ9609 |
| site_id | AJ2 |
| Number of Residues | 37 |
| Details | binding site for residues 9Y0 B 612 and CDL N 604 |
| Chain | Residue |
| B | HIS21 |
| B | ALA25 |
| B | HIS37 |
| B | TRP38 |
| B | LEU54 |
| B | VAL58 |
| B | PHE129 |
| B | ARG366 |
| B | PRO367 |
| B | ARG368 |
| B | THR374 |
| B | SER378 |
| B | PHE389 |
| B | VAL422 |
| B | ALA426 |
| B | TRP429 |
| B | ALA430 |
| B | CDL603 |
| B | CDL605 |
| B | 9Y0606 |
| B | MQ9609 |
| C | MET288 |
| C | ARG293 |
| C | MQ9304 |
| K | 9YF202 |
| N | TYR20 |
| N | ALA25 |
| N | ARG28 |
| N | GLN29 |
| N | LEU213 |
| N | ILE218 |
| N | ALA221 |
| N | GLY224 |
| N | ALA225 |
| N | LEU229 |
| N | PHE232 |
| N | MQ9607 |
| site_id | AJ3 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide HEM N 602 and ARG N 126 |
| Chain | Residue |
| N | SER39 |
| N | PHE40 |
| N | GLY43 |
| N | PHE116 |
| N | ILE120 |
| N | VAL122 |
| N | HIS123 |
| N | LEU124 |
| N | ALA125 |
| N | ILE127 |
| N | PHE128 |
| N | PHE129 |
| N | THR130 |
| N | ALA132 |
| N | ASN140 |
| N | TRP141 |
| N | GLY144 |
| N | SER145 |
| N | LEU147 |
| N | HIS226 |
| N | VAL230 |
| N | HIS235 |
| N | THR236 |
| N | MQ9609 |
| site_id | AJ4 |
| Number of Residues | 29 |
| Details | binding site for Di-peptide HEA R 601 and ARG R 459 |
| Chain | Residue |
| R | TRP260 |
| R | VAL267 |
| R | TYR268 |
| R | ILE270 |
| R | ALA271 |
| R | HIS313 |
| R | HIS314 |
| R | THR337 |
| R | PHE342 |
| R | GLY373 |
| R | GLY376 |
| R | VAL377 |
| R | LEU379 |
| R | ALA380 |
| R | ASP385 |
| R | THR389 |
| R | ASP390 |
| R | SER391 |
| R | TYR392 |
| R | VAL394 |
| R | HIS397 |
| R | PHE398 |
| R | VAL401 |
| R | LEU402 |
| R | THR405 |
| R | PRO458 |
| R | ARG460 |
| R | TYR461 |
| R | HEA602 |
| site_id | AJ5 |
| Number of Residues | 33 |
| Details | binding site for Di-peptide HEA R 602 and ARG R 63 |
| Chain | Residue |
| R | PHE52 |
| R | GLY56 |
| R | LEU57 |
| R | ALA59 |
| R | LEU60 |
| R | PHE61 |
| R | MET62 |
| R | THR64 |
| R | GLU65 |
| R | ALA67 |
| R | PHE79 |
| R | PHE83 |
| R | HIS86 |
| R | MET90 |
| R | GLY150 |
| R | TRP151 |
| R | TYR392 |
| R | ILE395 |
| R | PHE398 |
| R | HIS399 |
| R | LEU402 |
| R | PHE403 |
| R | ILE406 |
| R | THR445 |
| R | PHE446 |
| R | GLN449 |
| R | ARG459 |
| R | ARG460 |
| R | SER477 |
| R | THR478 |
| R | LEU484 |
| R | GLY485 |
| R | MET488 |
| site_id | AJ6 |
| Number of Residues | 29 |
| Details | binding site for Di-peptide HEA R 602 and GLY R 56 |
| Chain | Residue |
| R | PHE52 |
| R | LEU53 |
| R | VAL54 |
| R | GLY55 |
| R | LEU57 |
| R | MET58 |
| R | ALA59 |
| R | LEU60 |
| R | MET62 |
| R | ARG63 |
| R | PHE79 |
| R | PHE83 |
| R | HIS86 |
| R | MET90 |
| R | GLY150 |
| R | TRP151 |
| R | TYR392 |
| R | ILE395 |
| R | PHE398 |
| R | HIS399 |
| R | LEU402 |
| R | PHE403 |
| R | ILE406 |
| R | PHE446 |
| R | ARG459 |
| R | ARG460 |
| R | LEU484 |
| R | GLY485 |
| R | MET488 |
| site_id | AJ7 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide PLM W 203 and CYS W 24 |
| Chain | Residue |
| R | PHE61 |
| R | GLN78 |
| R | GLN81 |
| R | PHE140 |
| R | PRO143 |
| W | SER25 |
| W | ALA26 |
| W | 9YF202 |
| W | 9XX204 |
| site_id | AJ8 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide 9XX W 204 and CYS W 24 |
| Chain | Residue |
| P | VAL71 |
| P | TRP74 |
| P | PHE75 |
| R | GLN78 |
| R | LEU134 |
| R | ILE137 |
| R | ILE141 |
| W | SER25 |
| W | ALA26 |
| W | 9Y0201 |
| W | 9YF202 |
| W | PLM203 |
| site_id | AJ9 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide PLM Z 301 and CYS Z 21 |
| Chain | Residue |
| N | TRP318 |
| N | GLU319 |
| P | ARG64 |
| Z | SER22 |
| Z | 9XX302 |
| site_id | AK1 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide 9XX Z 302 and CYS Z 21 |
| Chain | Residue |
| N | GLU319 |
| N | PHE320 |
| N | TYR321 |
| N | TRP332 |
| Z | SER22 |
| Z | PLM301 |
Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 55 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyiialpffgivseifpvfsrkpifgyttliyatlaiaalsvavwa..HH |
| Chain | Residue | Details |
| F | TRP260-HIS314 |
| site_id | PS00078 |
| Number of Residues | 55 |
| Details | COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHgfwvpeflfkrdvlpepkannsdnvfqvseiqqtgafvgrCtemCgtfHamM |
| Chain | Residue | Details |
| E | VAL230-MET284 |
| site_id | PS00332 |
| Number of Residues | 12 |
| Details | SOD_CU_ZN_2 Copper/Zinc superoxide dismutase signature 2. GDAGsRvACgvI |
| Chain | Residue | Details |
| Y | GLY222-ILE233 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20094657 |
| Chain | Residue | Details |
| J | LYS115 | |
| V | LYS115 |
