6ADD
The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with CoA and NLQ
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004042 | molecular_function | L-glutamate N-acetyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0051289 | biological_process | protein homotetramerization |
| B | 0004042 | molecular_function | L-glutamate N-acetyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006526 | biological_process | L-arginine biosynthetic process |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0051289 | biological_process | protein homotetramerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | ASP7 |
| A | HIS90 |
| A | GLY91 |
| A | ILE92 |
| A | GLY93 |
| A | HIS94 |
| A | THR116 |
| A | GLU118 |
| A | PHE121 |
| A | ARG124 |
| A | NLQ202 |
| A | TYR30 |
| A | HOH322 |
| A | HOH334 |
| A | ILE34 |
| A | THR80 |
| A | VAL81 |
| A | ALA82 |
| A | VAL83 |
| A | THR88 |
| A | GLY89 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue NLQ A 202 |
| Chain | Residue |
| A | GLY32 |
| A | LYS33 |
| A | ILE34 |
| A | LEU36 |
| A | ARG79 |
| A | THR80 |
| A | LEU115 |
| A | GLU153 |
| A | COA201 |
| A | HOH301 |
| A | HOH321 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for residue COA B 201 |
| Chain | Residue |
| A | ASP106 |
| B | TYR30 |
| B | ILE34 |
| B | VAL81 |
| B | ALA82 |
| B | VAL83 |
| B | THR88 |
| B | GLY89 |
| B | HIS90 |
| B | GLY91 |
| B | ILE92 |
| B | GLY93 |
| B | HIS94 |
| B | THR116 |
| B | PHE121 |
| B | PHE122 |
| B | ARG124 |
| B | HOH330 |
| B | HOH331 |
| B | HOH355 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue NLQ B 202 |
| Chain | Residue |
| B | GLY32 |
| B | LYS33 |
| B | ILE34 |
| B | LEU35 |
| B | LEU36 |
| B | ARG79 |
| B | THR80 |
| B | LEU115 |
| B | GLU153 |
| B | HOH318 |
| B | HOH350 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 276 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
