6ABY
Crystal structure of citrate synthase (Msed_1522) from Metallosphaera sedula in complex with oxaloacetate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004108 | molecular_function | citrate (Si)-synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0036440 | molecular_function | citrate synthase activity |
| A | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| B | 0004108 | molecular_function | citrate (Si)-synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0036440 | molecular_function | citrate synthase activity |
| B | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue OAA B 401 |
| Chain | Residue |
| B | HIS179 |
| B | ASN182 |
| B | HIS253 |
| B | ARG262 |
| B | ARG332 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | TYR48 |
| B | GLU60 |
| B | HOH521 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue ACO B 403 |
| Chain | Residue |
| B | ARG247 |
| B | LEU248 |
| B | PHE251 |
| B | ARG300 |
| B | ILE302 |
| B | LEU242 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue OAA A 401 |
| Chain | Residue |
| A | HIS179 |
| A | ASN182 |
| A | HIS214 |
| A | HIS253 |
| A | ARG262 |
| A | PHE328 |
| A | ARG332 |
| A | HOH512 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | GLY110 |
| A | ASP197 |
| A | ILE198 |
| A | LEU344 |
| A | HOH532 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue ACO A 403 |
| Chain | Residue |
| A | GLU138 |
| A | ARG247 |
| A | LEU248 |
| A | PHE251 |
| A | ARG300 |
| A | ILE302 |
Functional Information from PROSITE/UniProt
| site_id | PS00480 |
| Number of Residues | 13 |
| Details | CITRATE_SYNTHASE Citrate synthase signature. GFGHrIy.KtmDPR |
| Chain | Residue | Details |
| B | GLY250-ARG262 |
